Device conforms to body’s tissues, allowing brain monitoring through development.
A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism that could be exploited for delivering other drugs.
Many malignant cancers overexpress a protein called P-cadherin, which is embedded in the cell membrane. Because cancer cells have a lot of P-cadherin sticking out of their surface, the protein has been targeted for drug development.
Monoclonal antibodies against P-cadherin can carry a drug payload to the cancer cells. It has not been clear, though, exactly how the antibodies attach to P-cadherin or how they get inside the cancer cell once attached.
By treating DNA as a language, Brian Hie’s “ChatGPT for genomes” could pick up patterns that humans can’t see, accelerating biological design.
Researchers have found that Artemisia herba-alba, a medicinal herb, contains compounds capable of fighting colorectal cancer. The plant extract halted cancer cell growth, disrupted key pathways, and showed potential as a less harmful alternative to chemotherapy.
Scientists from the University of Sharjah have discovered that Artemisia herba-alba, a naturally occurring aromatic herb, contains compounds with potential therapeutic effects against colorectal cancer.
This herb, commonly known as common wormwood, white wormwood, or herba alba, grows naturally in North Africa and the Middle East, where it has long been used in traditional medicine. Local populations have historically relied on it to treat conditions such as bronchitis, diarrhea, hypertension, and diabetes.
Some people will do anything to live forever: injecting young blood, freezing their heads, even zapping themselves with electricity in places you’d rather not imagine. On today’s episode of The Infographics Show, we’re diving into the strangest and most extreme attempts to cheat death, and why they might make you rethink wanting to live forever!
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Summary: New research reveals that brain cells use a muscle-like signaling mechanism to relay information over long distances. Scientists discovered that dendrites, the branch-like extensions of neurons, contain a structured network of contact sites that amplify calcium signals—similar to how muscles contract. These contact sites regulate calcium release, activating key proteins involved in learning and memory.
This mechanism explains how neurons process information received at specific points and relay it to the cell body. Understanding this process sheds light on synaptic plasticity, which underlies learning and memory formation. The findings could provide new insights into neurodegenerative diseases like Alzheimer’s.
Nerve cells have amazing strategies to save energy and still perform the most important of their tasks. Researchers from the University Hospital Bonn (UKB) and the University of Bonn as well as the University Medical Center Göttingen found that the neuronal energy conservation program determines the location and number of messenger RNA (mRNA) and proteins and differs depending on the length, longevity and other properties of the respective molecule. The work has now been published in Nature Communications.
We have all experienced the need to save energy in recent years. To do this, we all had to come up with strategies to save energy while still meeting our most important needs.
Our nerve cells are facing a similar dilemma: They have to supply their synapses, i.e., their contact points with other neurons, but also organize their protein synthesis in such a way that they don’t produce too much or too little proteins.
Mercedes-Benz recently presented a brand new solar paint technology that aims to improve an EV’s driving range through the use of solar power. In the best-case scenario, this novel evolution could probably enable EVs to produce sufficient electrical energy for about 20,000 km (12,427 miles) of yearly driving.
The Science Behind Mercedes Solar Paint
Solar paint is a new Mercedes-Benz innovation that embeds highly efficient photovoltaic plates into the car’s body. Unlike ordinary solar panels, commonly seen on rooftops, or as accessories, this paint facilitates conversion of sunlight into electricity without needing to change the car’s appearance. These are tiny photovoltaic cells that are embedded in paint to capture sunlight and convert it to electricity that is needed to recharge the electric vehicle’s battery.
Many describe this as the experience of seeing their life ‘flash before their eyes.’
The recording was made when an 87-year-old patient underwent cardiac arrest while being treated for epilepsy.
Doctors had strapped a device on his head to monitor brain activity, but the man died during the process.
Two hundred million years ago, our mammal ancestors developed a new brain feature: the neocortex. This stamp-sized piece of tissue (wrapped around a brain the size of a walnut) is the key to what humanity has become. Now, futurist Ray Kurzweil suggests, we should get ready for the next big leap in brain power, as we tap into the computing power in the cloud.
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