One in 7,000 people carry this gene mutation
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‘Only One Conclusion’: Radical Study Suggests Life on Earth Arose Twice
The fact that you, or I, or any living creature, is here at all is a series of astonishing strokes of luck stretching back more than 4 billion years.
One of the biggest hurdles was the very first one: How did life emerge from a primordial soup of stuff that very much wasn’t alive?
A radical new study, published in Science Advances, suggests that this unlikely threshold may actually have been crossed not once, but twice.
GLP-1 Drugs May Have a Hidden Effect on Your Eyes, Study Finds
GLP-1 drugs such as Ozempic have transformed healthcare in recent years, dramatically altering how we treat conditions like type 2 diabetes and obesity.
But while the medications are primarily used to help lower blood sugar and reduce appetite, scientists keep finding GLP-1 effects appear to extend much further, affecting our health in ways we never expected.
Now, a new study has uncovered another unintended effect, and it shows we’re still only scratching the surface of fully understanding how GLP-1 receptor agonists impact the body.
Engineered human neurons rebuild damaged spinal cord circuits
Spinal cord injuries affect an estimated 15 to 20 million people worldwide, often causing lasting impairments in movement, sensation and independence. Such injuries can be especially devastating when they occur at the level of the neck, where damaged spinal circuits disrupt signals that control the diaphragm, the main muscle used for breathing.
Despite advances in emergency care and rehabilitation, no approved therapies exist to rebuild the neurons and connections lost after a spinal cord injury. But new research from scientists at Gladstone Institutes offers hope for a regenerative treatment in the future.
The study, published in Science Translational Medicine, shows that human stem cell-derived spinal interneurons—cells that are critical for breathing and movement— can survive after being transplanted in injured rats, connect with the animals’ own neural circuits and improve breathing-related motor function.
Roman Aqueducts: A 2,000-Year-Old Water System 💧
It can be done again…
Building Biostasis Organizations to Last
No one can predict with any confidence how long it will be before it may be possible to repair and revive patients in biostasis. It is plausible that it will take a century. It could be decades less – especially if artificial intelligence accelerates biomedical advances – or it could be decades longer. But one century gives us something to work with. It is a long time in terms of changes in the world.
This raises an obvious question: How can a biostasis organization survive for a century or more until its patients can be returned to life?
How to Protect Your Telomeres for Healthy Aging and Longevity
Telomere shortening is associated with increased risk of disease and decreased lifespan. Various nutrients have been shown to support the length and health of telomeres in clinical and preclinical studies.
Scientifically reviewed by: Gary Gonzalez, MD, in May 2026. Written by: Richard Ross.
What Can We Learn From the Most Genetically Modified Human Alive? | Liz Parrish
In 2015, Liz Parrish flew to Colombia and let someone inject an untested gene therapy into her body 150 times. She texted her kids that she loved them before it started. When it was over, she went for nachos.
Ten years later, her telomeres are longer than when she started, and she has taken 12 gene therapies in total.
Her decade of self-experimentation has produced peer-reviewed data, a growing protocol of gene therapies, and a company training its sights on making biological aging optional. Our conversation goes over what it took to become patient zero and what gene therapy for aging looks like in practice today, among other things.