Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Long-read sequencing technologies analyze long, continuous stretches of DNA. These methods have the potential to improve researchers’ ability to detect complex genetic alterations in cancer genomes. However, the complex structure of cancer genomes means that standard analysis tools, including existing methods specifically developed to analyze long-read sequencing data, often fall short, leading to false-positive results and unreliable interpretations of the data.

These misleading results can compromise our understanding of how tumors evolve, respond to treatment, and ultimately how patients are diagnosed and treated.

To address this challenge, researchers developed SAVANA, a new algorithm which they describe in the journal Nature Methods.

Read more | >

The brain is a unique place. It is shielded from much of the body by the blood-brain barrier, meaning it’s protected from pathogens and potentially dangerous substances that might be in our blood. And historically, many scientists believed that separation extended to the immune system as well: the brain has its own specialized immune cells called microglia, but immune cells present in the rest of the body were long thought to steer clear of the brain unless there was a disease or other problem requiring their presence.

Now, a team of scientists from Yale School of Medicine (YSM) has shown that known as T cells reside in the healthy brains of mice and humans, trafficked there from the gut and fat. This is the first time T cells have been shown to inhabit the brain under normal, non-diseased conditions.

The findings are published in Nature.

Read more | >

A “fine-tuned” artificial intelligence (AI) tool shows promise for objective evaluation of patients with facial palsy, reports an experimental study in the June issue of Plastic and Reconstructive Surgery.

“We believe that our research offers valuable insights into the realm of facial palsy evaluation and presents a significant advancement in leveraging AI for clinical applications,” comments lead author Takeichiro Kimura, MD, of Kyorin University, Mitaka, Tokyo.

Patients with facial palsy have paralysis or partial loss of movement of the face, caused by nerve injury due to tumors, surgery, trauma, or other causes. Detailed assessment is essential for evaluating , such as nerve transfer surgery, but poses difficult challenges.

Read more | >

The natural protein, known as CelOCE, was developed at the Brazilian Center for Research in Energy and Materials and is ready for immediate integration into industrial processes. Breaking down plant material into usable fuel has long been one of science’s biggest energy challenges. At the heart o

Read more | >

A research team led by physicists Ming Yi and Emilia Morosan from Rice University has developed a new material with unique electronic properties that could enable more powerful and energy-efficient electronic devices.

The material, known as a Kramers nodal line metal, was produced by introducing a small amount of indium into a layered compound based on tantalum and sulfur. The addition of indium changes the symmetry of the crystal structure, and the result promotes the novel physical properties associated with the Kramers nodal line behavior. The research, published in Nature Communications, represents a step toward low-energy-loss electronics and paves the way for more sustainable technologies.

“Our work provides a clear path for discovering and designing new quantum materials with desirable properties for future electronics,” said Yi, associate professor of physics and astronomy.

Read more | >

An SMU-led research team has developed a more cost-effective, energy-efficient material called high-entropy oxide (HEO) nanoribbons that can resist heat, corrosion and other harsh conditions better than current materials.

These HEO nanoribbons— featured in the journal Science —can be especially useful in fields like aerospace, energy, and electronics, where materials need to perform well in extreme conditions.

And unlike high entropy materials that have been created in the past, the nanoribbons that SMU’s Amin Salehi-Khojin and his team developed can be 3D-printed or spray-coated at room temperature for manufacturing components or coating surfaces. This makes them more energy-efficient and cost-effective than traditional high-entropy materials, which typically exist as bulk structures and require high-temperature casting.

Read more | >

Lightweight, powerful lithium-ion batteries are crucial for the transition to electric vehicles, and global demand for lithium is set to grow rapidly over the next 25 years. A new analysis from the University of California, Davis, published May 29 in Nature Sustainability, looks at how new mining operations and battery recycling could meet that demand. Recycling could play a big role in easing supply constraints, the researchers found.

“Batteries are an enormous new source of demand for ,” said Alissa Kendall, the Ray B. Krone endowed professor of Environmental Engineering at UC Davis and senior author on the paper.

Lithium is a relatively common mineral and up to about 10 years ago demand was relatively small and steady, with a small number of mines providing the world’s supply, Kendall said. Global demand for lithium has risen dramatically—by 30% between 2022 and 2023 alone—as adoption of continues.

Read more | >