Lifeboat Foundation

Today, we have a new paper that discusses how induced pluripotency and cellular senescence, two of several possible cellular states, share similarities[2]. It is likely no surprise that the two states are closely related and that some of the mechanisms for one process are shared by the other. It appears that certain key signaling molecules are important in determining both cell fate and senescence.

Controlling cell behavior in living animals

As our understanding of guiding cell fate grows rapidly by the passing year, it has huge implications for therapies that seek to control cellular activities and encourage certain types of cells to be created. Research is now starting to move beyond the petri dish and to where cells are being programmed in situ in living animals.

Continue reading “The Link Between Cellular Senescence and Cellular Reprogramming” »

Dr. Oliver Medvedik Vice President of LEAF appears in this new TED interview where he talks about aging research and the possibilities of future medicine.

Aging happens to all of us, but scientists still don’t know the mechanism behind it. We need to focus on finding an answer, says molecular biologist Oliver Medvedik.

If given the option, would you choose to live forever? Many of us would say “yes,” but with one major caveat: just as long we don’t age. In scientific terms, aging means “a progressive loss of fitness in an organism over time,” says molecular biologist and TED Fellow Oliver Medvedik. What causes this loss of fitness in humans is multifaceted, although scientists are exploring different theories including — and these are just a few of the many avenues of research — the deterioration of the health of our telomeres (the ends of our chromosomes), changes in cell mitochondria, inefficient clearance of damaged cell proteins, and the senescence of stem cells, leading to chronic inflammation and a depletion of stem cells.

Continue reading “A crowdfunding platform aims to solve the puzzle of aging” »

China is planning to build a 13.8 billion yuan ($2.1 billion) technology park dedicated to developing artificial intelligence (AI), state-backed news agency Xinhua reported Wednesday.

Last year, China laid out plans to become a world leader in AI by 2030.

WASHINGTON — The public’s idea of a war in space is almost entirely a product of Hollywood fantasy: Interstellar empires battling to conquer the cosmos, spaceships going head to head in pitched dogfights.

The reality of how nations will fight in space is much duller and blander. And some of the key players in these conflicts will be hackers and lawyers.

Savvy space warriors like Russia’s military already are giving us a taste of the future. They are jamming GPS navigation signals, electronically disrupting satellite communications links and sensors in space. Not quite star wars. [The Most Dangerous Space Weapons Concepts Ever].

Continue reading “Sorry Sci-Fi Fans, Real Wars in Space Not the Stuff of Hollywood” »

In a basement laboratory, two robotocists have harnessed the sensing, swimming, and swarming abilities of bacteria to power microscopic robots. Who dares to unleash this madness?

To the best of our knowledge, we humans can only experience this world in three spatial dimensions (plus one time dimension): up and down, left and right, and forward and backward. But in two physics labs, scientists have found a way to represent a fourth spatial dimension.

This isn’t a fourth dimension that you can disappear into or anything like that. Instead, two teams of physicists engineered special two-dimensional setups, one with ultra-cold atoms and another with light particles. Both cases demonstrated different but complementary outcomes that looked the same as something called the “quantum Hall effect” occurring in four dimensions. These experiments could have important implications to fundamental science, or even allow engineers to access higher-dimension physics in our lower-dimension world.

Continue reading “Two Experiments Show Fourth Spatial Dimension Effect” »

New transhumanism story with many people in it. Forget the criticism in article, read what the highlighted people have said about the future. Great stuff.

A growing number of wealthy, tech-minded futurists are imagining life beyond their mortal bodies. We created images to match their strange, and varied, visions.

Speed breeding was initially explored by NASA over a decade ago as a means to enhance food production during space missions where efficiency is critical and every square inch counts. Scientists at the University of Sydney, the University of Queensland, and the John Innes Centre, continued the project, picking up from where NASA left off.

A welcomed solution to our growing food problems.

In the basement of the Engineering Center at the University of Colorado Boulder, a group of researchers is working to create the next generation of robots. Instead of the metallic droids you may be imagining, they are developing robots made from soft materials that are more similar to biological systems. Such soft robots contain tremendous potential for future applications as they adapt to dynamic environments and are well-suited to closely interact with humans.

A central challenge in this field known as “soft robotics” is a lack of actuators or “artificial muscles” that can replicate the versatility and performance of the real thing. However, the Keplinger Research Group in the College of Engineering and Applied Science has now developed a new class of soft, electrically activated devices capable of mimicking the expansion and contraction of natural muscles. These devices, which can be constructed from a wide range of low-cost materials, are able to self-sense their movements and self-heal from electrical damage, representing a major advance in soft robotics.

The newly developed hydraulically amplified self-healing electrostatic (HASEL) actuators eschew the bulky, rigid pistons and motors of conventional robots for soft structures that react to applied voltage with a wide range of motions. The soft devices can perform a variety of tasks, including grasping delicate objects such as a raspberry and a raw egg, as well as lifting heavy objects. HASEL actuators exceed or match the strength, speed and efficiency of biological muscle and their versatility may enable artificial muscles for human-like robots and a next generation of prosthetic limbs.

Continue reading “New class of soft, electrically activated devices mimics the expansion and contraction of natural muscles” »