Lifeboat Foundation

When the gene-editing technology CRISPR first made a splash back in 2012, it foretold a future in which curing diseases might simply involve snipping out problematic bits of genetic code. Of course, innovation is rarely so straightforward. As incredible as CRISPR is, it also has some pretty sizable flaws to overcome before it can live up to its hype as a veritable cure-all for human disease.

A new study published this week in the journal Nature Genetics tackles one CRISPR complication. CRISPR gene-editing systems can easily cut many pieces of DNA at once, but actually editing all those genes is a lot more time-consuming. Now, scientists at UCLA have come up with a way to edit multiple genes at once.

When scientists use CRISPR for genetic engineering, they are really using a system made up of several parts. CRISPR is a tool taken from bacterial immune systems. When a virus invades, the bacterial immune system sends an enzyme like Cas9 to the virus and chops it up. The bacteria then adds short bits of virus DNA to its own code, so it can recognize that virus quickly in the future. If the virus shows up again, a guide RNA will lead the Cas9 enzyme to the matching place in the virus code, where it again chops it up. In CRISPR, when that cutting is done, scientists can also insert a new bit of code or delete code, to, for example, fix disease-causing genetic mutations in the code before patching it up. But delivering that new code and making the patch is where it can get especially tricky.

Continue reading “Scientists Edit Thousands of Genes at Once With Upgraded CRISPR” »

Stretch of road outside Stockholm transfers energy from two tracks of rail in the road, recharging the batteries of electric cars and trucks.

A new drug that blocks a molecule that cancer cells rely on for transcribing genetic information shows promise in tackling treatment-resistant tumors.

Very interesting.

Vostok (Russian for ‘East’) was a Soviet human spaceflight project that developed the Vostok spacecraft which was used to place the first human in space.

The first manned US spacecraft was Mercury, which was first launched in suborbital flights on Redstone rockets and then in orbital missions on Atlas launchers.

Continue reading “Timeline of early spaceflights” »

ALBUQUERQUE, NM – Applied Research Associates, Inc. (ARA) is developing a compact, completely self-contained directed-energy weapon that is the first of its size and specifications, making it a standout from existing systems.

The Silent Saber is high power, 1.5 kilowatt fiber laser packaged in a backpack with power supplies and a unique thermal control system. A telescope with multiple potential mounting configurations can be mounted to existing Picatinny rails of a soldier’s rifle, and a laser is connected to the telescope by a fiber cable.

“This tool provides options to the warfighter to support explosive ordnance disposal, counter infrastructure and counter drone missions,” said Principal Engineer Joseph Paranto, ARA’s Director of Directed Energy Systems.

Click on photo to start video.

Face-swapping videos could lead to more “fake news.”

Volcanologists use samples from Eyjafjallajökull in Iceland to recreate famous hexagonal columns in laboratory.

Hannah Devlin Science correspondent.

Will lead to very interesting weather.

The sun just developed three new holes – with a spectrum of effects expected.

Space.

Continue reading “Holey moly! Three holes have burst open on the sun hurtling geomagnetic storms towards Earth” »

Contrary to certain sensationalist articles declaring that video games are harmful, there is, in fact, growing evidence that playing video games may have a positive effect on cognitive health, particularly in older people [1].

Today, we will be taking a look at the scientific evidence to see if brain training or hitting your favorite video game titles could help keep you healthy as you age.