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Jun 8, 2023

Fatty liver disease is a serious problem. Here’s who should be worried about it

Posted by in category: biotech/medical

Dr. Blanca Lizaola-Mayo, MD, a transplant hepatologist and the Medical Director of the Liver Transplant Center at the Mayo Clinic in Arizona, is sounding the alarm on NASH or nonalcoholic steatohepatitis.

NASH occurs when a “fatty liver” or nonalcoholic fatty liver disease (NAFLD) leads to inflammation and liver cell damage called fibrosis. In its most severe form, it can be fatal.

Jun 8, 2023

Teaching robots to tidy up based on user preferences using large language models

Posted by in categories: habitats, robotics/AI

Different people tend to have unique needs and preferences—particularly when it comes to cleaning or tidying up. Home robots, especially robots designed to help humans with house chores, should ideally be able to complete tasks in ways that account for these individual preferences.

Researchers at Princeton University and Stanford University recently set out to personalize the assistance offered by home robots using large language models (LLMs), a class of artificial intelligence models that are becoming increasingly popular after the release of ChatGPT. Their approach, presented in a paper pre-published on arXiv, was initially tested on a called TidyBot engineered to tidy up indoor environments.

“For a robot to personalize physical assistance effectively, it must learn user preferences that can be generally reapplied to ,” Jimmy Wu, Rika Antonova and their colleagues wrote in their paper. “In this work, we investigate personalization of household cleanup with robots that can tidy up rooms by picking up objects and putting them away.”

Jun 8, 2023

Seagate Tests 5 Terabyte Disks, Paving the Way for 50TB Hard Drives

Posted by in category: computing

We’ll get 32TB, 36TB, and 40TB hard drives first, though.

Jun 8, 2023

Healthy diets and weight loss may help reduce brain aging

Posted by in categories: life extension, neuroscience

Researchers have found that well-managed weight through a healthy diet, including Mediterranean-type diets, can help reduce brain aging and improve brain health.

Jun 8, 2023

Brain Tumors Can Rewire The Brain, And We Just Found Out How

Posted by in categories: biotech/medical, neuroscience

Researchers have long known that brain tumors, specifically a type of tumor called a glioma, can affect a person’s cognitive and physical function.

Patients with glioblastoma, the most fatal type of brain tumor in adults, experience an especially drastic decline in quality of life. Glioblastomas are thought to impair normal brain functions by compressing and causing healthy tissue to swell, or competing with them for blood supply.

Continue reading “Brain Tumors Can Rewire The Brain, And We Just Found Out How” »

Jun 8, 2023

Researchers build on Human Genome Project advances

Posted by in categories: biotech/medical, chemistry, genetics, government

The Human Genome Project (HGP), the world’s largest collaborative biological project, was a 13-year effort led by the U.S. government with the goal of generating the first full sequence of the human genome. In 2003, HGP produced a genome sequence that accounted for more than 90% of the human genome and was considered as close to complete as was possible with the technologies of the time. HGP unlocked the door to a vast but unannotated collection of genes.

In the following decades, via experimental studies, researchers painstakingly curated reannotations in the form of biochemical reaction graphs. Though gene set enrichment analysis considers groups within these annotation graphs, it disregards group dependencies.

Researchers from the University of Hawaii at Mānoa John A. Burns School of Medicine (JABSOM) are utilizing data from HGP and making advancements in biochemical reaction network analysis. Their work, published in the May 22, 2023 issue of Patterns, demonstrates their approach and may help predict the effects of rare or indistinct genetic variations and guide precision medicine (treatment that can use a patient’s own to help fight disease or guide specific therapy).

Jun 8, 2023

Sugar, Metabolism & Cancer — How is metabolic syndrome linked to cancer?

Posted by in categories: biotech/medical, food, health

Dr. Moss and his son Ben discuss the most important cancer and general health-related topic of all, SUGAR, and the problems it has caused in their lives as well as for more than 50% of adults in the United States and other industrialized countries. They share their personal experiences and the science that clearly connects sugar to cancer, metabolic syndrome, and diabetes.

Program Notes:
For more information on cancer-fighting foods and supplements, please visit our website:

Continue reading “Sugar, Metabolism & Cancer — How is metabolic syndrome linked to cancer?” »

Jun 8, 2023

Coronavirus variant XBB.1.5 rises in the United States — is it a global threat?

Posted by in category: biotech/medical

I still think it is a threat globally and it based on many cases globally that still rise at an alarming rate.

Prevalence of a new subvariant of Omicron is increasing, but whether it will cause a big surge in infections or hospitalizations isn’t clear.

Jun 8, 2023

Melanoma vaccine trial appears to reduce skin cancer recurrence

Posted by in category: biotech/medical

Drug companies Moderna and Merck have released encouraging results from a vaccine trial that shows promise in the battle against Stage 3 and Stage 4 melanoma, the most serious type of skin cancer. NBC’s Dr. Natalie Azar breaks down the findings on TODAY.

Jun 8, 2023

Impact of COVID-19 vaccination on the use of PD-1 inhibitor in treating patients with cancer: a real-world study

Posted by in category: biotech/medical

PD-1 inhibitors have been widely used for treatment of multiple types of cancer. 1 With the ongoing coronavirus pandemic, the effect of anti-COVID-19 vaccination on PD-1 safety and efficacy has become a critical question for oncologists and patients with cancer alike. 2 To avoid potential treatment complications, some physicians have opted to suspend PD-1 inhibitor treatments for recently vaccinated patients with cancer. However, little data exist to support such a decision. Recent studies have found that anti-COVID-19 vaccines such as BNT162b2 (Pfizer BioNTech, New York, New York, USA) and mRNA-1273 (Moderna, Cambridge, Massachusetts, USA) are well tolerated in patients with cancer, 3–5 and side-effect profiles from these vaccines were similar between healthy volunteers and patients with cancer. 6 One recent meta-analysis summarizing multiple COVID-19 vaccine trials studies concluded that patients with cancer have a significantly lower likelihood of attaining acceptable immune response to COVID-19 immunization when compared with the general population given compromised cancerous immune system. 7 However, whether anti-COVID-19 vaccines have any functional impact on the efficacy of immune checkpoint inhibitor (ICI) treatment was unknown. Thus, we conducted a large multicenter study to explore the effects of COVID-19 vaccination on PD-1 inhibitor treatment in patients with cancer.

A total of 3,552 consenting adult patients with cancer were screened from 83 Chinese hospitals and medical centers beginning on January 28, 2021. Eligible participants met the following inclusion criteria: their malignancy had been histopathologically confirmed; they had received at least one dose of camrelizumab8 (one of the most commonly used PD-1 inhibitors in China) after the COVID-19 vaccination program was launched in China in January 2021. Clinical information, demographic data, and medical history were collected at enrollment, and patient treatment, adverse events and outcomes were followed through September 30, 2021. Efficacy and safety of PD-1 treatment were evaluated according to Response Evaluation Criteria in Solid Tumor V.1.19 and National Cancer Institute Common Terminology Criteria for Adverse Events V.5.0,10 respectively. Patient functionality/performance status was evaluated using Eastern Cooperative Oncology Group (ECOG) criteria.

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