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Jul 4, 2018

Manipulating the Immune System for Cancer Immunotherapy

Posted by in categories: biotech/medical, life extension

Researchers have manipulated the immune system to respond more aggressively to cancer according to a new study [1].

Manipulating macrophages

We have discussed modulating the immune system multiple times recently, especially in regards to macrophages and manipulating their behavior. Macrophages are part of the innate immune system and carry out a wide variety of tasks, such as clearing away cell debris, engulfing pathogens, facilitating tissue growth, and disposing of senescent cells once other immune cells have destroyed them.

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Jul 4, 2018

Interviews with Arie (Bionic technique) and Zoltan (Transhumanist)

Posted by in categories: cyborgs, transhumanism


Future Flux Festival 2018 was a blast!

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Jul 4, 2018

Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity

Posted by in categories: genetics, life extension

Life extension genetics.

Many factors contribute to exceptional longevity, with genetics playing a significant role. However, to date, genetic studies examining exceptional longevity have been inconclusive. This comprehensive review seeks to determine the genetic variants associated with exceptional longevity by undertaking meta-analyses.

Meta-analyses of genetic polymorphisms previously associated with exceptional longevity (85+) were undertaken. For each variant, meta-analyses were performed if there were data from at least three independent studies available, including two unpublished additional cohorts.

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Jul 4, 2018

Why Fans Might Have To Wait For Season 4 Of ‘The Expanse’ After The Sci-Fi Drama’s Amazon Revival

Posted by in categories: alien life, electronics

Life on Mars will continue after all. After three seasons on cable television, the Syfy space war drama The Expanse was given the axe on May 10. Since then, support from the show’s fans has helped it find new life: The series has officially been renewed by Amazon for Season 4, which will be streamable. That’s right — not only will the sci-fi favorite return, but it is now marathon material. So, when is The Expanse Season 4? A premiere date has not yet been announced, but one thing is for sure — fans and The Expanse cast members alike can’t get enough of the show’s revival.

The Expanse, based on the New York Times bestselling eight-part book series co-written by Daniel Abraham and Ty Franck under the pen name James S. A. Corey, is set in a fully colonized solar system on the brink of war. There are three main parties that make up this narrative — Earth, Mars, and the asteroid belt — and their biggest mission is universal peace. Just like Rome wasn’t built in a day, though, universal peace wasn’t achieved in three seasons, so it only makes sense that Amazon picked up the story for continuation on a new platform.

It helps that Amazon CEO Jeff Bezos is a big fan of the books on which the show is based, according to the Hollywood Reporter, and he wasn’t ready to see the TV series go. He made the public announcement on May 25 at a National Space Society panel where the show’s cast and crew were in attendance.

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Jul 3, 2018

Aneutronic Fusion Reactor

Posted by in category: nuclear energy

Nuclear fusion reactor — clean, safe, and environmentally friendly atomic energy.

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Jul 3, 2018

Did Something Massive Smash Into Uranus?

Posted by in categories: energy, space

Uranus really is strange. Not only does it rotate on an axis that sits at a 98-degree angle to its orbital plane, but, unlike the other giant planets, it doesn’t appear to release more heat than it receives from the Sun. Its magnetic field, too, appears warped compared to the Earth’s. An impact could perhaps help explain some of these strange traits.

Scientists have been simulating giant impacts into Uranus since the early 1990s, according to the new paper published in the Astrophysical Journal. This time around, researchers built a new simulation with the newest and best available data of the planet’s composition. This allowed them to model how a giant impactor, perhaps one to three times the mass of Earth, would have deposited “material and energy inside Uranus” and how much debris would be left over, from which moons could form.

“This study provides some great new insights into what might have happened all those billions of years ago, with material left over from the impact possibly even serving to trap some of that heat inside,” Leigh Fletcher, Royal Society Research Fellow at the University of Leicester, told Gizmodo.

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Jul 3, 2018

Scientists find gene linking Down syndrome, early Alzheimer’s

Posted by in categories: biotech/medical, neuroscience

British researchers are zeroing in on genes they believe are responsible for early onset Alzheimer’s disease in people with Down syndrome.

WEDNESDAY, July 3, 2018 — British researchers are zeroing in on the genes that they believe are responsible for early onset Alzheimer’s disease in people with Down syndrome.

The two conditions have long been strongly linked.

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Jul 3, 2018

New Liberty Science Center exhibit puts you in the distracted driver’s seat

Posted by in categories: mobile phones, science, transportation, virtual reality

After living through a car accident, I think this raises excellent awareness!

Exhibits at the Liberty Science Center in Jersey City usually produce awe and wonder. A new interactive exhibit at LSC, however, gives the participant a grim and horrific look at the results of distracted driving. The AT&T 2018 It Can Wait Tour, a 3D virtual reality exhibit, will be at the science center from Friday, July 6 to through Tuesday, July 10, from 10 a.m. to 5:30 p.m. each day. The exhibit uses virtual reality technology to simulate the potentially deadly consequences of using a phone while driving. The exhibit also features a memorial wall, a wall of keys representing lives lost and a wall made to look like crushed car parts. The Liberty Science Center is located at 222 Jersey City Boulevard.

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Jul 3, 2018

We know ocean plastic is a problem. We can’t fix it until we answer these 5 questions

Posted by in category: materials

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Jul 3, 2018

Human stem cells give monkey hearts a boost after heart attacks, study says

Posted by in categories: biotech/medical, life extension

Following heart attacks, a handful of monkeys regained some of the pumping ability their hearts had lost after being given human embryonic stem cells, according to a study published Monday in Nature Biotechnology.

Scientists have tried for years to develop a stem cell treatment for heart disease caused by lack of blood flow, which contributed to more than 9.4 million deaths worldwide in 2016, according to the World Health Organization.

“We’re talking about the number one cause of death in the world [for humans],” said study author Dr. Charles Murry, director of the Institute for Stem Cell and Regenerative Medicine at the University of Washington. “And at the moment all of our treatments are … dancing around the root problem, which is that you don’t have enough muscle cells.”

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