Lifeboat Foundation

The facility, which was originally used by the US military to spy on Soviet satellites during the Cold War, is undergoing a major overhaul to attract tourists and researchers alike. In search of inspiration, Snøhetta’s designers took astronomy classes and were captivated by the architecture of the galaxy.

“We learned about the eight shaped analemma diagram that the moon and the sun makes if you watch them from the same point over 365 days,” says Skaare. “We were especially inspired by the ‘ugly moons’ of Mars, with its funny shape,” she says referring Phobos and Deimos, the red-planet’s two lumpy satellites.

Mars’s lumpy-potato moons, in fact, inspired the shape of Solobservatoriet’s visitor cabins. Surrounding the planetarium are several imperfect-sphere rooms for stargazers who want to spend the an evening in the forest—perhaps to catch the spectacular Northern Lights. Designed to accommodate groups of two to 32, the cabins will be loosely scattered around the planetarium, by design.

Continue reading “A spectacular destination for astronomy fans is being built in rural Norway” »

As demand for natural gas continues to surge, huge extraction vessels are about to go into action.

A landmark study has revealed that cholesterol in the brain may play a fundamental role in catalyzing the formation of amyloid beta clusters, thought to be a central mechanism leading to the devastating degenerative symptoms of Alzheimer’s disease.

An international team of researchers, led by the University of Cambridge, set out to uncover what causes amyloid beta proteins to cluster into the plaques that slowly accumulate and cause the primary degenerative symptoms of Alzheimer’s disease.

“The levels of amyloid-beta normally found in the brain are about a thousand times lower than we require to observe it aggregating in the laboratory – so what happens in the brain to make it aggregate?” asks Michele Vendruscolo, lead on the new research.

The eruption of Kilauea Volcano on the island of Hawaii triggered a number of gas- and lava-oozing fissures in the East Riff Zone of the volcano. The fissures and high levels of sulfur dioxide gas prompted evacuations in the area.

Images taken from the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) onboard NASA’s Terra satellite picked up these new fissures. In the first image, the red areas are vegetation, and the black and gray areas are old lava flows. The yellow areas superimposed over the image show hot spots that were detected by ASTER’s thermal infrared bands. These hot spots are the newly formed fissures and new lava flow as of May 6. In the second photo, also acquired on May 6, the long yellow and green streaks are plumes of sulfur dioxide gas.

On April 30, the floor of Kilauea’s crater began to collapse. Earthquakes followed, including one that measured magnitude 6.9, and lava was pushed into new underground areas that eventually broke through the ground in such areas as the Leilani Estates.

http://toosickandnaked.com/2018/05/07/25-the-future-of-medic…-bioquark/

Summary: A new study sheds light on how the cerebellum is able to make predictions and learn from mistakes, especially when it comes to completing complex motor actions. The findings could help in the development of new machine learning technologies.

Source: Johns Hopkins Medicine.

In studies with monkeys, Johns Hopkins researchers report that they have uncovered significant new details about how the cerebellum — the “learning machine” of the mammalian brain — makes predictions and learns from its mistakes, helping us execute complex motor actions such as accurately shooting a basketball into a net or focusing your eyes on an object across the room.

Silicon Valley’s Drive.ai is starting a pilot program to ferry office workers around a small area of Frisco, with vehicles that can “chat” with passers-by.

Rates of HTLV-1, an ancient virus called the cousin of HIV, are exceeding 40% among adults in remote regions of central Australia. Doctors are now raising alarm about this “neglected” infection.

Aging is characterized by the progressive increase in chronic, low‐grade inflammation termed “inflammaging,” which is believed to play an important role in the mechanism underlying aging.

Necroptosis is a newly identified programmed cell death pathway that is highly proinflammatory due to the release of cellular components that promote inflammation. To determine whether necroptosis might play a role in inflammaging, we studied the effect of age and dietary restriction (DR) on necroptosis in the epididymal white adipose tissue (eWAT), a major source of proinflammatory cytokines. Phosphorylated MLKL and RIPK3, markers of necroptosis, were increased 2.7‐ and 1.9‐fold, respectively, in eWAT of old mice compared to adult mice, and DR reduced P‐MLKL and P‐RIPK3 to levels similar to adult mice. An increase in the expression of RIPK1 (1.6‐fold) and MLKL (2.7‐fold), not RIPK3, was also observed in eWAT of old mice, which was reduced by DR in old mice. The increase in necroptosis was paralleled by an increase in 14 inflammatory cytokines, including the pro‐inflammatory cytokines IL‐6 (3.9‐fold), TNF‐α (4.7‐fold), and IL‐1β (5.1‐fold)], and 11 chemokines in old mice. DR attenuated the expression of IL‐6, TNF‐α, and IL‐1β as well as 85% of the other cytokines/chemokines induced with age. In contrast, inguinal WAT (iWAT), which is less inflammatory, did not show any significant increase with age in the levels of P‐MLKL and MLKL or inflammatory cytokines/chemokines. Because the changes in biomarkers of necroptosis in eWAT with age and DR paralleled the changes in the expression of pro‐inflammatory cytokines, our data support the possibility that necroptosis might play a role in increased chronic inflammation observed with age.