Lifeboat Foundation

One of the most intriguing developments in the so-called golden age of neuroscience has been the growing understanding of “neuroplasticity”: the brain’s ability to constantly reshape itself and constantly learn new things by forging new connections throughout one’s lifetime — to grow proportions of gray matter and even shift brain activity to different regions of the brain.

Now a new research effort is taking the concept of neuroplasticity further — looking at diseased and injured brains that have permanently lost neurons. The effort, led by neuroscientist Magdalena Götz, explores whether “astrocytes” — non-neuronal, structural cells in the brain, can be reprogrammed to take up the tasks the neurons once performed.

“Everybody is astonished, at the moment, that it works,” says Nicola Mattugini, a neurobiologist at the Ludwig Maximilian University of Munich, Germany, when she presented her team’s results at the annual meeting of the Society for Neuroscience in San Diego, California. Their team reprogrammed the astrocytes in lab mice.

We’re continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology.

Sree Kant of Life Biosciences discussed investment and R&D in an aging world, demonstrating the necessity of rejuvenation biotechnology in keeping people over the age of 65 healthy and productive. He showed that we need effective treatments for the root causes of aging rather than just downstream conditions, bringing up the necessity of a broad rejuvenation ecosystem that uses VC and other investment to fund companies that focus on these root causes.

This is a clip from a conversation with Michio Kaku from Oct 2019. New full episodes once or twice a week and 1–2 new clips or a new non-podcast video on all other days. You can watch the full conversation here: https://www.youtube.com/watch?v=kD5yc1LQrpQ
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Continue reading “Michio Kaku: AI Will Help Us Discover Genetic Immortality | AI Podcast Clips” »

But there has never been a good explanation for this connection.

“It’s been known for a long time that sleep is really important for brain health,” Lewis says, “but why it is was more mysterious.”

Lewis and a team of researchers wanted to solve the mystery.

Machine learning provides an entirely new way to tackle one of the classic problems of applied mathematics.

As wildfires in California and elsewhere become the new normal, scientists are racing to learn the airborne health risks of the chemicals in our homes.

A pair of new studies report “impressive” benefits from a drug therapy for cystic fibrosis, a deadly and devastating disease that affects tens of thousands of people worldwide, the director of the National Institutes of Health wrote in an editorial published in The New England Journal of Medicine on Thursday.

“These findings indicate that it may soon be possible to offer safe and effective molecularly targeted therapies to 90 percent of persons with cystic fibrosis,” wrote the director, Dr. Francis S. Collins, who led the team that in 1989 identified the gene that causes the genetic disease affecting the lungs and digestive system.

“This should be a cause for major celebration,” he wrote in the Thursday editorial.

One-fifth the weight of steel but five times the strength, plant-based cellulose nanofiber (CNF) offers carmakers the opportunity to build strong, lightweight cars while sustainably removing as much as 2,000 kg (4,400 lb) of carbon from the car’s life cycle.

We’ve written before about the extraordinary properties of CNFs, which were last year demonstrated to be stronger than spider silk. Made essentially from wood, but chipped, pulped and boiled in chemicals to remove lignin and hemicellulose, it’s a highly condensed, lightweight and incredibly strong material that’s also very recyclable.

It can also, as it turns out, be used in manufacturing, where it can be injection molded as a resin-reinforced slurry to form complex shapes – and the Japanese Ministry of the Environment sees it as a potential way for automakers to reduce weight and sustainably reduce their carbon footprint.