Lifeboat Foundation

A common and inexpensive drug may be used to counteract treatment resistance in patients with acute myeloid leukemia (AML), one of the most common forms of blood cancer. This is the conclusion of a study in mice and human blood cells performed at Karolinska Institutet and SciLifeLab and published in the medical journal EMBO Molecular Medicine. The researchers will now launch a clinical study to test the new combination treatment in patients.

Leukemia is a group of blood cancers that results in excess amounts of white blood cells. There are both chronic forms of leukemia that progress slowly over many years and acute types of leukemia that evolve rapidly. AML affects more than 20,000 people in the United States each year, and the mortality rate is high especially in older patients.

One of the most common drugs to treat AML is cytarabine (ara-C), a cytotoxic drug that interferes with DNA replication. However, many patients do not respond to the treatment because their leukemic cells express high levels of the enzyme SAMHD1, which breaks down the active metabolite of cytarabine, ara-CTP. These patients have a significantly worse survival rate than patients with low leukemic levels of SAMHD1. Therefore, one promising strategy to improve the treatment of AML is to inhibit the effects of this enzyme on cytarabine.

Marilyn had extensive fusion surgery all the way from her midback to the entire lower back. The surgery was done to fix her curvature in her spine.

Unfortunately, it did not help and she continued to have pain.

Continue reading “Can Stem Cells salvage failed Spinal Fusion Surgeries?” »

The Fourth Industrial Revolution is underway — and it’s going to change everything. 🤖.

The chemicals, known as PFAS, have been associated with cancer, liver damage, and developmental issues.

Apple has reportedly paid $200 million to acquire Seattle-based artificial intelligence company Xnor.ai, which specialises in edge-based AI.

The purchase is one of many for Apple, which has become adept at vacuuming up tech startups, but it also gives us a glimpse into the company’s thinking when it comes to future devices.

Xnor.ai’s work on hyper-efficient, low-power AI that doesn’t require powerful processing or a connection to the cloud (processing locally on-device instead), neatly slots into a few areas Apple is currently working on.

A drone has become a welcomed addition to cinematography in recent years. With brand new ways to see the world, they provide us with new viewpoints deemed impossible only a few years ago. We can already see their impact when used in documentaries and recreational films: most new movies rely on the standard drone overhead shot used for establishing the scene and aesthetic.

Here are some of the coolest drone shots that have been posted online. Some of these explore views that have never been captured on film before, making for some amazing ways to see the world.

These two got close and personal to some pretty wild beasts in California. The girls were part of a documentary that explored the relationship between sharks and humans when they traveled on a paddleboard to see them.

Thing.

(TMU) — Bees are major fans of hemp and a recent study has found that the taller the hemp plants are the larger the number of bees that will flock to it.

Anyone with a modicum of skill can create deepfake videos using artificial intelligence, but experts suggest that AI may also be the solution that allows rapid and accurate identification and detection.

By now, most of us have shared a few chuckles over AI-generated deepfake videos, like those in which the face of comedian and impressionist Bill Hader gradually takes on the likenesses of Tom Cruise, Seth Rogen, and Arnold Schwarzenegger as he imitates the celebrities. We’ve seen actor Ryan Reynolds’ mug superimposed over Gene Wilder’s in the 1971 classic film “Willy Wonka & the Chocolate Factory.” We’ve even marveled over businessman Elon Musk being turned into a baby.

Continue reading “Deepfake video: It takes AI to beat AI” »