Lifeboat Foundation

Scientists from the UNC School of Medicine, Columbia University, and Rockefeller University have revealed the inner workings of one of the most fundamental and important molecular machines in cells.

The researchers, in a study published in Science, used biochemical experiments and cryo–electron microscopy (cryo-EM) to determine the atomic structure of a complex assembly of molecules known as the histone mRNA three-prime (3’) end-processing machine. This machine plays a fundamental role in proper activity and duplication of the cell genome and when defective, it may lead to human diseases, including cancers.

Histone proteins are found in all plants and animals, and they form a “beads-on-a-string” arrangement where the DNA in chromosomes is wrapped around the beads of histones. Histones ensure the efficient packaging of DNA and help regulate which genes are turned “on” and which are kept “off,” processes needed for all cells to function properly.

China has applied to patent a drug candidate being developed by US biotechnology firm Gilead Sciences in its search for a cure for coronavirus infection. It could raise questions on intellectual property and marketing rights.

Watch CD Projekt Red’s stream, where it will showcase a 15-minute version of Cyberpunk 2077’s recent gameplay demo, where we expect to get details on Night City, playstyles, and more.

Four newly-discovered species of shark are capable of trotting around on land, using four fins as stubby legs.

They’re the most recently-evolved types of sharks known to science, according to CNET. And while they still live in the water, using their fins to crawl across coral reefs, they can briefly wriggle across dry land to migrate from one tide pool to another.

NASA’s Christina Koch returned to Earth safely on Thursday after shattering the spaceflight record for female astronauts with a stay of almost 11 months aboard the International Space Station.

Koch touched down at 0912 GMT on the Kazakh steppe after 328 days in space, along with Luca Parmitano of the European Space Agency and Alexander Skvortsov of the Russian space agency.

Koch was shown seated and smiling broadly after being extracted from the Soyuz descent module in the Roscosmos space agency’s video footage from the landing site.

MDMA and psilocybin have been granted breakthrough therapy status by the FDA, signaling a shift in the future of mental health treatment.

Clinical studies are underway. How we treat them moving forward matters.

Thoughts?

Despite centuries of colonization and agriculture, Cuba’s rivers are in good health.

Sugarcane and cattle farming on the island date back to the late fifteenth century. To measure water quality in Cuba’s rivers today, Paul Bierman at the University of Vermont in Burlington, Rita Hernández at the Cienfuegos Center for Environmental Studies in Cuba and their colleagues sampled water in 25 river basins in central Cuba. This is the first time in more than 60 years that scientists from Cuba and the United States have joined forces to study the island’s hydrology.

Continue reading “Cuba’s rivers run clean after decades of sustainable farming” »

The YangDAO was created specifically to allow the Yang Gang community to coordinate and fund projects that we decide are in our shared interest, whether that’s a Federal Meme Reserve 🏛, Freedom Dividend pilots 💰, or that new MATH blockbuster movie 🎬.

Cue in MolochDAO. Launched as a decentralized autonomous organization (DAO) by SpankChain co-founder and chief executive officer Ameen Soleimani earlier this year, MolochDAO puts members’ ether (ETH) tributes toward funding Ethereum projects that members vote on.

The can-do, do-it-yourself attitude of the group has proven popular in the Ethereum community and has already influenced several spinoffs, leading some to credit Moloch with a resurgence in Ethereum DAOs.

On August 16th, the DAO’s associated Twitter account reflected on what the group has accomplished in its first six months in operation.