Lifeboat Foundation

To me cryonics just makes sense. It may not be pretty but, just like open heart surgery, it is one of those things that, without any guarantees, can possibly extend your life [very] substantially. Thus, especially given the alternative, I just can’t quite make sense of the slow rate of adoption evident not only in North America but also across the world. And so I am always happy to discover new books that lay out the scientific argument for cryonics while making it easily digestible and giving it a very personal, human perspective. Since the most recent book, I thoroughly enjoyed on this topic was Frozen to Life: A Personal Mortality Experiment I thought that D.J. MacLennan will make an excellent guest on my podcast. I was not wrong about that.

During our 1 hour conversation with D.j. MacLennan we cover a variety of interesting topics such as: why he decided to write Frozen to Life and who is it for; cryonics as a glass-state time travel; why he chose neuro- rather than full-body preservation; the costs and rate of adoption of cryonics; the culture, conservatism and geography of his home on the Isle of Skye; transhumanism and transcending limitations; the differences between Max More and James Hughes; his fear of death; the promise of chemical brain preservation; mindfulness and meditation; writing a transhumanist take on The Wizard of Oz and potentially on Grim’s Fairy Tales…

As always you can listen to or download the audio file above or scroll down and watch the video interview in full. To show your support you can write a review on iTunes, make a direct donation or become a patron on Patreon.

The Born rule, which connects the math of quantum theory to the outcomes of experiments, has been derived from simpler physical principles. The new work promises to give researchers a better grip on the core mystery of quantum mechanics.

A broad-spectrum look at the future of phages.

Pancreatic cancer is especially challenging to treat—only eight percent of patients are still alive five years after diagnosis. Chemotherapy and radiation therapy are of limited benefit, and even immunotherapy—which revolutionized treatment for other kinds of cancer by activating the body’s immune system to attack cancer cells—has been largely ineffective because pancreatic tumors have ways to dampen the immune assault.

Now, researchers at Washington University School of Medicine in St. Louis and Rush University in Chicago have found a chemical compound that promotes a vigorous immune assault against the deadly cancer. Alone, the compound reduces pancreatic tumor growth and metastases in mice. But when combined with immunotherapy, the compound significantly shrank tumors and dramatically improved survival in the animals.

The findings, published July 3 in Science Translational Medicine, suggest that the immune-boosting compound could potentially make resistant pancreatic cancers susceptible to immunotherapy and improve treatment options for people with the devastating disease.

Galaxy clusters are some of the most massive structures in the cosmos, but despite being millions of lightyears across, they can still be hard to spot. Researchers at Lancaster University have turned to artificial intelligence for assistance, developing “Deep-CEE” (Deep Learning for Galaxy Cluster Extraction and Evaluation), a novel deep learning technique to speed up the process of finding them. Matthew Chan, a Ph.D. student at Lancaster University, is presenting this work at the Royal Astronomical Society’s National Astronomy meeting on 4 July at 3:45pm in the Machine Learning in Astrophysics session.

Most galaxies in the universe live in low-density environments known as “the field”, or in small groups, like the one that contains our Milky Way and Andromeda. Galaxy clusters are rarer, but they represent the most extreme environments that galaxies can live in and studying them can help us better understand dark matter and dark energy.

During 1950s the pioneer of galaxy cluster-finding, astronomer George Abell, spent many years searching for galaxy clusters by eye, using a magnifying lens and photographic plates to locate them. Abell manually analysed around 2,000 photographic plates, looking for visual signatures the of galaxy clusters, and detailing the astronomical coordinates of the dense regions of galaxies. His work resulted in the ‘Abell catalogue’ of galaxy clusters found in the northern hemisphere.

When I was kid I used to watch the Incredible Hulk on TV and wait for Bruce Banner to fly into a rage, his muscles inflating like balloons, pants torn to shreds while his entire body turns green as he transforms into the Hulk. As I grew up, and learned more about the advances in genetics, it never occurred to me that cutting-edge genome-editing techniques could explain the scientific principles behind the Hulk’s metamorphosis or his fellow Marvel Comics star-spangled hero Captain America. In a recent Stanford Report story, Sebastian Alvarado Opens in a new window, a postdoctoral research fellow in biology, creatively applies the concepts of epigenetics to illuminate the process by which average Joes become superheroes.

As Alvarado notes in the piece Opens in a new window and above video, over the past 70 years scientists have developed tools for selectively activating and deactivating individual genes through chemical reactions, a process termed epigenetics. Similar to flipping on a light, switch gene expression can be “turned on” or “turned off. ”We have a lot of genome-editing tools – like zinc finger nucleases, or CRISPR/Cas9 systems – that could theoretically allow you to epigenetically seek out and turn on genes that make your muscles physically large, make you strategically minded, incredibly fast, or increase your stamina,” he said.

Continue reading “Using epigenetics to explain how Captain America and the Incredible Hulk gained their superpowers” »

Photons — those fundamental particles of light — have a slew of interesting properties, including the fact they don’t tend to crash into one another. That hasn’t stopped physicists from trying, though.

University of Chicago physicists have now come up with a new, highly flexible way to make photons behave more like the particles that make up matter. It might not give us lightsabers, but making photons collide could still lead to some fantastic technologies.

The trick to getting particles of light — which have no mass — to acknowledge one another’s existence is to have them meet in the quiet confines of an atom, and combine their properties with those of an electron.

Feldman creates mathematical models that reveal how cultural traditions can affect the evolution of a species.

• By Elizabeth Svoboda, Quanta Magazine on January 12, 2017

You know that spherical ship from 2001: A Space Odyssey that generated its own gravity by spinning around in the cosmic void? We’re not there yet, but we’re getting closer.

Microgravity can be detrimental for the human body, because our species just wasn’t made to survive in space without high-tech help. Now aerospace engineer Torin Clark and his team from CU Boulder are turning the artificial gravity tech from movies like 2001 and The Martian into a reality. While an entire ship that makes its own gravity is still light-years away, the team has managed to design a revolving contraption that could save astronauts from too much zero-G exposure.

Continue reading “This artificial gravity machine is right out of 2001: A Space Odyssey” »