Lifeboat Foundation

On August 22nd, spaceflight startup Momentus Space and launch heavyweight SpaceX announced the first public launch contract to fall under the umbrella of the latter company’s recently-announced Satellite Rideshare Program.

Meant to provide a reliable, consistent, and affordable form of shuttle-like access to orbit, SpaceX’s rideshare program will – pending demand – involve no less than one dedicated Falcon 9 launch per year, capable of placing 15+ metric tons (33,000+ lbs) into low Earth orbit. Although SpaceX’s rideshare proposal is far from revolutionary, the company’s contract with Momentus Space appears to be more than a basic launch service agreement, potentially opening doors for far more flexible rideshare launches in the future.

Since its November 2017 founding, Momentus Space has been able to put money where its mouth is far more so than any comparable space tug hopeful, of which there are several. The concept that has helped Momentus raise nearly $34M in just 1.5 years is relatively simple: build a spacecraft whose sole purpose is to propel other spacecraft to their final orbit(s).

Small-scale soft continuum robots capable of active steering and navigation in a remotely controllable manner hold great promise in diverse areas, particularly in medical applications. Existing continuum robots, however, are often limited to millimeter or centimeter scales due to miniaturization challenges inherent in conventional actuation mechanisms, such as pulling mechanical wires, inflating pneumatic or hydraulic chambers, or embedding rigid magnets for manipulation. In addition, the friction experienced by the continuum robots during navigation poses another challenge for their applications. Here, we present a submillimeter-scale, self-lubricating soft continuum robot with omnidirectional steering and navigating capabilities based on magnetic actuation, which are enabled by programming ferromagnetic domains in its soft body while growing hydrogel skin on its surface. The robot’s body, composed of a homogeneous continuum of a soft polymer matrix with uniformly dispersed ferromagnetic microparticles, can be miniaturized below a few hundreds of micrometers in diameter, and the hydrogel skin reduces the friction by more than 10 times. We demonstrate the capability of navigating through complex and constrained environments, such as a tortuous cerebrovascular phantom with multiple aneurysms. We further demonstrate additional functionalities, such as steerable laser delivery through a functional core incorporated in the robot’s body. Given their compact, self-contained actuation and intuitive manipulation, our ferromagnetic soft continuum robots may open avenues to minimally invasive robotic surgery for previously inaccessible lesions, thereby addressing challenges and unmet needs in healthcare.

Small-scale soft continuum robots capable of navigating through complex and constrained environments hold promise for medical applications (1–3) across the human body (Fig. 1A). Several continuum robot concepts have been commercialized so far, offering a range of therapeutic and diagnostic procedures that are safer for patients owing to their minimally invasive nature (4–6). Surgeons benefit from remotely controlled continuum robots, which allow them to work away from the radiation source required for real-time imaging during operations (5, 6).

Despite these advantages, existing continuum robots are often limited to relatively large scales due to miniaturization challenges inherent in their conventional actuation mechanisms, such as pulling mechanical wires or controlling embedded rigid magnets for manipulation. Tendon-driven continuum robots (7–10) with antagonistic pairs of wires are difficult to scale down to submillimeter diameters due to increasing complexities in the fabrication process as the components become smaller (11–13). The miniaturization challenges have rendered even the most advanced form of commercialized continuum robots, mostly for cardiac and peripheral interventions (14), unsuited for neurosurgical applications due to the considerably smaller and more tortuous vascular structures. Magnetically steerable continuum robots (15–19) have also remained at large scale because of the finite size of the embedded magnets required to generate deflection under applied magnetic fields.

Learn about the latest product and platform innovations at Google in a Keynote led by Sundar Pichai.

Watch more #io19 here:

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Synthetic biological circuits are promising tools for developing sophisticated systems for medical, industrial, and environmental applications. So far, circuit implementations commonly rely on gene expression regulation for information processing using digital logic. Here, we present a different approach for biological computation through metabolic circuits designed by computer-aided tools, implemented in both whole-cell and cell-free systems. We first combine metabolic transducers to build an analog adder, a device that sums up the concentrations of multiple input metabolites. Next, we build a weighted adder where the contributions of the different metabolites to the sum can be adjusted. Using a computational model fitted on experimental data, we finally implement two four-input perceptrons for desired binary classification of metabolite combinations by applying model-predicted weights to the metabolic perceptron. The perceptron-mediated neural computing introduced here lays the groundwork for more advanced metabolic circuits for rapid and scalable multiplex sensing.

Hmmmm.

ATTENTION owners of truly massive, human-built tunnels and subterranean complexes: The US military’s secretive research agency urgently needs your underground lair for some undisclosed experiments.

DARPA tweeted on Wednesday that within the next 48 hours it must find a “human-made underground environment spanning several city blocks with complex layout & multiple stories, including atriums, tunnels & stairwells. Spaces that are currently closed off from pedestrians or can be temporarily used for testing are of interest.”

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Police in a small Texas community have recommended that residents temporarily vacate their homes on Monday while Elon Musk Elon Reeve MuskUS Space Command: A vision for the final frontier The paradox of superstars Hillicon Valley: US, France reach deal on tech tax | FEC vice chair resigns | Move leaves agency unable to vote on actions | Groups seek net neutrality pledge from 2020 Dems | Australia eyes blocking extremist content MORE ’s SpaceX attempts an experimental launch of a Mars rocket prototype.

A public safety notice was issued to residents of Boca Chica, a town on the southern tip of Texas with houses within two miles of SpaceX’s launch pad for the Starhopper rocket, Business Insider reported on Sunday.

A county sheriff reportedly went door-to-door on Saturday to deliver the notice to approximately 20 households, warning of possible shattered windows and “potential risk to health and safety.”

Just imagine what types of treatments, human enhancements, and other disorders could be solved with this technique. No more invasive GBM surgeries, Dystonia is finally treated and no longer a problem as well as other diseases and disorders that are located in areas like the basal ganglia area of the brain.

By Chris Stokel-Walker

A tiny robotic worm can wiggle its way through a model brain. It could eventually be used to make brain surgeries less invasive.

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During his year in space, Scott Kelly was zapped relentlessly by radiation — the equivalent of 10 chest X-rays a day for more than 11 months starting in March of 2015. The onslaught damaged the astronaut’s DNA and affected his immune system while raising his risk for cancer. And Kelly was aboard the International Space Station, whose tight orbit around Earth lies within the magnetic field that surrounds our planet and blocks the most damaging forms of radiation.

Astronauts who travel to Mars or other destinations in deep space will leave Earth’s protective cocoon for months or years at a time. And a new NASA-funded study suggests that chronic exposure to radiation could harm astronauts’ minds as well as their bodies — potentially affecting space flyers’ moods and even their ability to think.

That could be a big deal.

One of the most difficult challenges in treating the brain cancer glioblastoma is that few drugs can pass through the blood-brain barrier. Scientists at Cedars-Sinai in Los Angeles have developed a system to circumvent this hurdle—one that combines a powerful immuno-oncology drug with a polymer-based delivery vehicle that can cross the blood-brain barrier.

The researchers showed that this “nano-immunotherapy” treatment crossed the blood-brain barrier in mouse models of glioblastoma, and that it stopped tumor cells from multiplying. They published their findings in the journal Nature Communications.

The Cedars-Sinai team used the polymer scaffold to deliver two types of immune checkpoint inhibitors, blocking either CTLA-4 or PD-1. When injected into the bloodstream of mice, the drugs quickly infiltrated brain tumors, but not healthy brain tissue, the researchers reported.