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Jan 2, 2020

Novel dementia vaccine on track for human trials within two years

Posted by in categories: bioengineering, biotech/medical, neuroscience

A newly published study has described the successful results in mice of a novel vaccine designed to prevent neurodegeneration associated with Alzheimer’s disease. The researchers suggest this “dementia vaccine” is now ready for human trials, and if successful could become the “breakthrough of the next decade.”

The new study, led by the Institute for Molecular Medicine and University of California, Irvine, describes the effect of a vaccine designed to generate antibodies that both prevent, and remove, the aggregation of amyloid and tau proteins in the brain. The accumulation of these two proteins is thought to be the primary pathological cause of neurodegeneration associated with Alzheimer’s disease.

The research revealed the vaccine led to significant decreases in both tau and amyloid accumulation in the brains of bigenic mice engineered to exhibit aggregations of these toxic proteins. Many prior failed Alzheimer’s treatments over the past few years have focused individually on either amyloid or tau protein reductions, but growing evidence suggests a synergistic relationship between the two toxic proteins may be driving neurodegeneration. Hence the hypothesis a combination therapy may be the most effective way to prevent this kind of dementia.

Jan 2, 2020

BWX Technologies, Inc. | People Strong, Innovation Driven

Posted by in categories: government, nuclear energy

NUCLEAR THERMAL PROPULSION


BWX Technologies, Inc. is a leading supplier of nuclear components and fuel to the U.S. government, also providing components and services to the commercial nuclear power industry.

Jan 2, 2020

There’s a Giant Mystery Hiding Inside Every Atom in the Universe

Posted by in categories: particle physics, space

No one really knows what happens inside an atom. But two competing groups of scientists think they’ve figured it out. And both are racing to prove that their own vision is correct.

Here’s what we know for sure: Electrons whiz around “orbitals” in an atom’s outer shell. Then there’s a whole lot of empty space. And then, right in the center of that space, there’s a tiny nucleus — a dense knot of protons and neutrons that give the atom most of its mass. Those protons and neutrons cluster together, bound by what’s called the strong force. And the numbers of those protons and neutrons determine whether the atom is iron or oxygen or xenon, and whether it’s radioactive or stable.

Jan 2, 2020

Italian Longevity League

Posted by in category: life extension

The ILA welcomes its new federated member – the Italian Longevity League, Italy!

https://ec.europa.eu/eip/ageing/sites/eipaha/themes/eiponaha2/logo.png]

http://www.longevityalliance.org/?q=partners

Jan 2, 2020

Doctors Believe Health Supplement Led to 23-Year-Old’s Acute Liver Failure

Posted by in categories: biotech/medical, food, health

WHAT SAY YE??? Beware, so many do not care if they kill you to make money from their snake oil products… r.p.berry & AEWR.


Doctors believe a health food supplement caused acute liver failure in an otherwise healthy 23-year-old Amarillo woman.

Emily Goss is starting the new year, with a new routine. She checks her vitals to make sure her body isn’t rejecting the new liver doctors implanted Christmas Day in an effort to save her life.

Continue reading “Doctors Believe Health Supplement Led to 23-Year-Old’s Acute Liver Failure” »

Jan 2, 2020

Scientists Brought Brains Brought Back to Life Four Hours After Death

Posted by in category: neuroscience

#13 in our top science stories of 2019.

Jan 2, 2020

5 Important Features of Your Brain, According to a Top Neuroscientist

Posted by in category: neuroscience

https://youtube.com/watch?v=Tnr4EyTegcs

In his new book, The Deep History of Ourselves: The Four-Billion-Year Story of How We Got Our Conscious Brains, neuroscientist Joseph Ledoux assigns himself the simple tasks of explaining how consciousness developed and redefining how we create and experience emotions.

Obviously, I’m being facetious. There’s nothing simple about these tasks, yet in Ledoux’s capable hands the reader is led, step by step, through the past four billion years of life on this planet. Consciousness, a phenomenon responsible for your ability to read and understand these words (as well as much, much more), often feels like a given, yet that’s only because human life is short and evolution is so very long.

Continue reading “5 Important Features of Your Brain, According to a Top Neuroscientist” »

Jan 2, 2020

Scientists Working on Brain-Like Memory Device

Posted by in categories: materials, neuroscience

An international joint research team led by National Institute for Materials Science in Japan is currently developing a brain-like memory device using the neuromorphic network material.

Jan 2, 2020

‘Leak’ May Reveal Russia’s Answer To The Virginia Class Attack Submarine

Posted by in categories: military, robotics/AI

A Russian State-owned TV channel recently aired a segment which may give the first glimpse of a new Russian submarine design. In the corner of one scene (@ 2.48 minutes into the recording) it showed an official model of a new submarine together with previously known types. The Laika Class sub has until now been shrouded in secrecy. It is generally analogous to the Virginia Class attack submarine in service with the U.S. Navy.

Such a ‘leak’ was probably deliberate, something that Russia has been suspected of before. On November 9, 2015, Russian TV station NTV revealed the Poseidon Intercontinental Nuclear-Powered Nuclear-Armed Autonomous Torpedo to the world. Then called ‘Status-6,’ it was seen over the shoulder of an officer in a partially televised meeting with President Putin.

The new sub will primarily be a hunter-killer, meaning that it is designed to counter western nuclear-powered submarines. But it will also carry a range of cruise missiles, including the hypersonic Zircon.

Jan 2, 2020

Story of the Year: Humanity’s First Look at a Black Hole

Posted by in categories: cosmology, media & arts, transportation

The image, and resulting data, has helped astronomers learn more about black holes in general, and this one in particular, making that two-year wait more than worthwhile. Part of the reason for the delay was simply the logistics of gathering so many observations. Each observatory collects data over a narrow range of wavelengths, resulting in massive amounts of information — the equivalent of up to 5,000 years of mp3 music files. That’s too much to just email someone. Researchers instead had to find ways to physically move that data around. For instance, to transport the information out of the South Pole Telescope in Antarctica, scientists had to wait until spring, when planes finally started flying out again.

Only then could researchers begin the complicated process of stitching together data from the eight observatories, a technique known as interferometry. The team had their work cut out for them: Raw files from each of the observing sites came in with different angles on the sky, in different wavelengths and at different observation times.

“The calibrating and working with it took many months,” Özel says. “And at the end we synthesize it into a single image.” But that’s still not the end of the work, she says. “[You] spend another six months worrying about all the things you might have done wrong, and ask yourself more and more questions, until finally you can be certain that what you have is real.”