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Nov 26, 2019

Japan and Singapore Grant CRISPR Patents to Merck

Posted by in category: biotech/medical

Merck now holds 22 CRISPR-related patents worldwide across nine different geographies.

- Patents cover Paired Cas9 Nickase CRISPR genome-editing technology to advance gene therapy and research.

DARMSTADT, Germany, Nov. 26, 2019 /PRNewswire/ — Merck, a leading science and technology company, today announced that the Japan Patent Office and the Intellectual Property Office of Singapore have each allowed the company’s patent application for the use of paired CRISPR nickases, bringing Merck’s number of patents to 22 worldwide.

Nov 26, 2019

Inside the Boeing Orca XLUUV unmanned submarine

Posted by in categories: military, robotics/AI

The US Navy has awarded Boeing contracts worth a total of $274.4m to produce five Orca Extra Large Unmanned Undersea Vehicles (XLUUVs). Based on Boeing’s Echo Voyager prototype UUV, the 15.5m-long submersible could be used for mine countermeasures, anti-submarine warfare, anti-surface warfare, electronic warfare and strike missions. Berenice Baker finds out more.

Nov 26, 2019

Low-impact treadmill

Posted by in category: futurism

Apparently the world needed an underwater treadmill…

Nov 26, 2019

Michelin unveils airless 3D-printed tires that last virtually forever

Posted by in category: 3D printing

The Michelin Vision tire concept does not need to be inflated, is specifically manufactured through 3D printing, and is biodegradable.

Nov 26, 2019

Microsoft says new Dexphot malware infected more than 80,000 computers

Posted by in categories: cryptocurrencies, cybercrime/malcode

Microsoft security engineers detailed today a new malware strain that has been infecting Windows computers since October 2018 to hijack their resources to mine cryptocurrency and generate revenue for the attackers.

Named Dexphot, this malware reached its peak in mid-June this year, when its botnet reached almost 80,000 infected computers.

Since then, the number of daily infections has been slowly going down, as Microsoft claims it deployed countermeasures to improve detections and stop attacks.

Nov 26, 2019

The Psychology of Beating an Incurable Illness | Bob Cafaro | TEDxCharlottesville

Posted by in categories: biotech/medical, media & arts, neuroscience

NOTE FROM TED: Please do not look to this talk for medical advice. This talk, which was filmed at a TEDx event, contains strong assertions about multiple sclerosis and lifestyle medicine that lack sufficient scientific evidence for general prescription. TEDx events are independently organized by volunteers. The guidelines we give TEDx organizers are described in more detail here: http://storage.ted.com/tedx/manuals/tedx_content_guidelines.pdf

After a shocking diagnosis that would begin stripping Bob Cafaro of his ability to perform, sheer willpower and changes to his daily life allow him to beat all odds.

Continue reading “The Psychology of Beating an Incurable Illness | Bob Cafaro | TEDxCharlottesville” »

Nov 26, 2019

10th class Indian student creates a device that can predict heart attack in advance

Posted by in category: biotech/medical

Akash Manoj started reading medical books written by global writers only for fun when he was in the 8th class. And just after two years, this child has taken the medical scientists by surprise as he has developed a device to predict ‘silent’ heart attacks. This disease kills thousands of people every year in India alone.

Just after the complition of his 7th class exams, Akash began to visit fairly well-known libraries in Bangalore and he gradually fell in love with medical novels.

“Journal articles are expensive, so visiting the libraries was the only way I could do it. Otherwise, it would have cost more than a crore (of rupees) for the amount I read. I was always interested in medical science and I liked reading the journals…cardiology is my favourite,” said Manoj.

Nov 26, 2019

Investigators narrow in on a microRNA for treating multiple sclerosis

Posted by in categories: biotech/medical, neuroscience

It turns out the gut is full of surprises. And one of those surprises may have offered up a key for unlocking a new way of treating multiple sclerosis (MS). Investigators from Brigham and Women’s Hospital have discovered a microRNA—a small RNA molecule—that increases during peak disease in a mouse model of MS and in untreated MS patients. When a synthetic version of the microRNA was orally given to the mice, it prevented disease. While several steps remain before these insights can be translated into therapy for patients, the researchers describe their results as both exciting and unexpected. Their findings are published in Cell Host & Microbe.

“We’ve discovered a new mechanism to regulate the microbiome and treat that hadn’t been known before,” said senior author Howard Weiner, MD, co-director of the Ann Romney Center for Neurologic Diseases at the Brigham. “The is known to play an important role in MS and other diseases. Our findings, which show that a microRNA can be used to target and influence the microbiome with precision, may have applicability for MS and many other diseases, including diabetes, ALS, obesity and cancer.”

Weiner, lead author Shirong Liu, MD, Ph.D., an instructor in the Weiner laboratory, and their colleagues investigated how the altered gut microbiome affects the course of MS. To do so, they studied the microbiome and microRNAs found in the experimental autoimmune encephalomyelitis (EAE) model of MS. Unexpectedly, they found that when they transferred fecal matter from EAE mice at peak disease, it protected the mice who received the transfer. The team found that a specific microRNA, known as miR-30d, rather than live bacteria, was responsible for preventing disease. The investigators found that miR-30d is enriched in untreated, relapsing-remitting MS patients as well.

Nov 26, 2019

PLANAT National Platform for Natural Hazards Information platform on natural hazards in Switzerland [Measures EB]

Posted by in category: futurism

Essentially good layers of sediment can decrease earthquake frequency.


Central information platform on natural hazards and their management in Switzerland. Background information about different types of natural hazards, information for experts/authorities and images, publications, information about events, links and much more.

Nov 26, 2019

Controlling earthQuakes | CoQuake Project | H2020

Posted by in category: futurism

This would solve California’s earthquake problem.


H2020,coquake, ERC-2017-STG, ECOLE NATIONALE DES PONTS ET CHAUSSEES(FR)