Menu

Blog

Page 7380

Nov 18, 2019

“Surprising” new insights into link between gut microbiome and aging

Posted by in categories: biotech/medical, life extension, neuroscience

A new study is suggesting a metabolite produced by gut microbes could increase neuron production in the brain, improve intestinal function, and ultimately slow the aging process. Across several compelling mouse experiments the research found the negative effects of aging could be counteracted by enhanced microbial production of a molecule called butyrate.

Investigating the effect of the gut microbiome on aging, the new research first performed gut microbiome transplants between old and young mice. Using fecal transplants, young germ-free mice were colonized with the gut microbiota of older mice. The results were somewhat unexpected as the younger mice colonized with the older microbiomes displayed increased neurogenesis, a process whereby new neurons are produced in the brain.

“We’ve found that microbes collected from an old mouse have the capacity to support neural growth in a younger mouse,” explains Sven Pettersson, lead on the research team from Nanyang Technological University in Singapore. “This is a surprising and very interesting observation…”

Nov 18, 2019

Quitting smoking could lead to major changes in gut bacteria

Posted by in category: health

Quitting smoking leads to major changes in intestinal bacteria, according to new research. But just what the changes mean will need further investigation.

The small pilot study, to be presented during the American Heart Association’s Scientific Sessions in Philadelphia, comes in the wake of past research showing a link between bacteria in the gut and cardiovascular health. That past work has shown is associated with a decrease in diversity in the types of beneficial bacteria living in the gut.

For the new study, researchers looked at 26 people who were trying to quit smoking and analyzed their stool samples at the start of the study and again two weeks and 12 weeks later.

Nov 18, 2019

Press Release

Posted by in categories: biotech/medical, business, life extension

Award Program Honors the Achievement.

MOUNTAIN VIEW November 11, 2019 — Sens Research Foundation has been selected for the 2019 Best of Mountain View Award in the Medical Laboratory category by the Mountain View Award Program.

Each year, the Mountain View Award Program identifies companies that we believe have achieved exceptional marketing success in their local community and business category. These are local companies that enhance the positive image of small business through service to their customers and our community. These exceptional companies help make the Mountain View area a great place to live, work and play.

Nov 18, 2019

The measurements of the expansion of the universe don’t add up

Posted by in categories: cosmology, evolution, physics

Physicists use two types of measurements to calculate the expansion rate of the universe, but their results do not coincide, which may make it necessary to update the cosmological model. “It’s like trying to thread a cosmic needle,” explains researcher Licia Verde of the University of Barcelona, co-author of an article on the implications of this problem.

More than a hundred scientists met this summer at the Kavli Institute for Theoretical Physics at the University of California (U.S.) to try to clarify what is happening with the discordant data on the expansion rate of the , an issue that affects the very origin, evolution and fate of our cosmos. Their conclusions have been published in Nature Astronomy journal.

“The problem lies in the Hubble constant (H0), a parameter which value—it is actually not a constant because it changes with time—indicates how fast the Universe is currently expanding,” points out cosmologist Licia Verde, an ICREA researcher at the Institute of Cosmos Sciences of the University of Barcelona (ICC-UB) and the main author of the article.

Nov 18, 2019

Hibernation Could Reduce Spacecraft Size For Human Trips To Mars, Says ESA

Posted by in category: space travel

ESA is getting serious about how hibernation could be used on long-duration space flights.

Nov 18, 2019

An artificial intelligence algorithm can learn the laws of quantum mechanics

Posted by in categories: chemistry, information science, quantum physics, robotics/AI

Artificial intelligence can be used to predict molecular wave functions and the electronic properties of molecules. This innovative AI method developed by a team of researchers at the University of Warwick, the Technical University of Berlin and the University of Luxembourg, could be used to speed-up the design of drug molecules or new materials.

Artificial intelligence and are routinely used to predict our purchasing behavior and to recognize our faces or handwriting. In , Artificial Intelligence is establishing itself as a crucial tool for scientific discovery.

In chemistry, AI has become instrumental in predicting the outcomes of experiments or simulations of quantum systems. To achieve this, AI needs to be able to systematically incorporate the fundamental laws of .

Nov 18, 2019

Fuel cell drone makes an epic ocean crossing

Posted by in categories: biotech/medical, drones

Although multicopter drones now are being used to transport medical samples and supplies, their 30-minute (or so) battery life limits their range. This week, however, a hydrogen-powered delivery drone managed a one-hour, 43-minute ocean crossing.

The exercise was the result of a collaboration between Texas-based drone development company Guinn Partners, Georgia-based Skyfire Consulting, the US Department of Health, and drone manufacturer Doosan Mobility Innovation – the latter supplied the aircraft, a hydrogen fuel cell-powered DS30 octocopter.

Utilizing its temperature-controlled payload system, the drone was used to transport live bacteria samples from a hospital on the Caribbean island of St. Croix to a testing facility on the neighboring island of St. Thomas. This involved crossing 43 miles (69 km) of open ocean. Upon successfully reaching its destination, the copter reportedly still had almost 30 minutes of flight time left on its fuel cell.

Nov 18, 2019

Scientists 3D Print Skin That Develops Working Blood Vessels

Posted by in categories: 3D printing, biotech/medical

Get the best of Smithsonian.com by email. Keep up-to-date on:

Nov 18, 2019

Podcast #37: The Future of Nursing and Caregiving, Part Two, with Oriana Beaudet and Dan Pesut

Posted by in categories: futurism, robotics/AI

In part two of this 2-part series, Oriana Beaudet and Dan Pesut discuss a healthcare future that includes automation, artificial intelligence and robots. And what about potential disruptive futures that change everything?

Nov 18, 2019

Life-long epigenetic programming of cortical architecture

Posted by in categories: biotech/medical, evolution, food, genetics, life extension, neuroscience

The evolution of human diets led to preferences toward polyunsaturated fatty acid (PUFA) content with ‘Western’ diets enriched in ω-6 PUFAs. Mounting evidence points to ω-6 PUFA excess limiting metabolic and cognitive processes that define longevity in humans. When chosen during pregnancy, ω-6 PUFA-enriched ‘Western’ diets can reprogram maternal bodily metabolism with maternal nutrient supply precipitating the body-wide imprinting of molecular and cellular adaptations at the level of long-range intercellular signaling networks in the unborn fetus. Even though unfavorable neurological outcomes are amongst the most common complications of intrauterine ω-6 PUFA excess, cellular underpinnings of life-long modifications to brain architecture remain unknown. Here, we show that nutritional ω-6 PUFA-derived endocannabinoids desensitize CB1 cannabinoid receptors, thus inducing epigenetic repression of transcriptional regulatory networks controlling neuronal differentiation. We found that cortical neurons lose their positional identity and axonal selectivity when mouse fetuses are exposed to excess ω-6 PUFAs in utero. Conversion of ω-6 PUFAs into endocannabinoids disrupted the temporal precision of signaling at neuronal CB1 cannabinoid receptors, chiefly deregulating Stat3-dependent transcriptional cascades otherwise required to execute neuronal differentiation programs. Global proteomics identified the immunoglobulin family of cell adhesion molecules (IgCAMs) as direct substrates, with DNA methylation and chromatin accessibility profiling uncovering epigenetic reprogramming at 1400 sites in neurons after prolonged cannabinoid exposure. We found anxiety and depression-like behavioral traits to manifest in adult offspring, which is consistent with genetic models of reduced IgCAM expression, to suggest causality for cortical wiring defects. Overall, our data uncover a regulatory mechanism whose disruption by maternal food choices could limit an offspring’s brain function for life.


  • Immediate Communication
  • Published: 18 November 2019
    <li class=”” itemprop=“author” itemscope=“itemscope” itemtype=“http://schema.[/ul>