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Jul 29, 2020

Virgin Galactic reveals SpaceShipTwo cabin interior

Posted by in category: space travel

Virgin Galactic, a British aerospace and space travel company within the Virgin Group, today revealed the cabin interior of its SpaceShipTwo vehicle, VSS Unity in a virtual event streamed live on YouTube.

Jul 29, 2020

Waveguide quantum electrodynamics with superconducting artificial giant atoms

Posted by in categories: particle physics, quantum physics

Superconducting giant atoms are realized in a waveguide by coupling small atoms to the waveguide at multiple discrete locations, producing tunable atom–waveguide coupling and enabling decoherence-free interactions.

Jul 29, 2020

Brain Computer Interfaces Developed by DARPA, US Department of Defense

Posted by in categories: biotech/medical, cyborgs, military, neuroscience, robotics/AI

If you are interested in brain computer interfaces (BCI), then you need to listen to this very exciting podcast!

I have only been aware of this DARPA NNN (Next-generation Non-surgical Neurotechnology) program since mid-March, and it is my number one topic of interest. I am interested in it because I have a plan for mind uploading to extend my life indefinitely — otherwise known as superlongevity in our group — but I have no interest in allowing anyone to drill holes in my head! DARPA is looking at ways for non-invasive methods of connecting the thoughts in our brains to computers. Over time, this could be a method to capture the thoughts and memories and emotions within my mind and transfer them into a computer substrate. And, to be clear, this mind upload will, in fact, be me.

Continue reading “Brain Computer Interfaces Developed by DARPA, US Department of Defense” »

Jul 29, 2020

Roche’s Actemra Misses the Mark in Phase III COVID-19 Associated Pneumonia Study

Posted by in category: biotech/medical

Roches Actemra failed to meet its primary and secondary endpoints in a late-stage study involving hospitalized patients with severe COVID-19 associated pneumonia. The drug also failed to hit a key secondary endpoint of reduced patient mortality.

Genentech, the South San Francisco-based Roche subsidiary, launched the Phase III COVACTA study of Actemra, a rheumatoid arthritis drug, in March for this indication. The COVACTA study marked the first global study of Actemra (tocilizumab) plus standard-of-care in this setting. Actemra is an IL-6 inhibitor. The IL-6 protein triggers the body’s immune and inflammatory response to fight infections. But, in the case of those patients where their immune system overreacts, such as in some COVID-19 patients, inhibiting IL-6 could keep the body from attacking itself.

This morning, Genentech announced that COVACTA did not meet its primary endpoint of improved clinical status in hospitalized adult patients with severe COVID-19 associated pneumonia. In addition, the key secondary endpoints, which included the difference in patient mortality at week four, were not met. However, there was a positive trend in time to hospital discharge in patients treated with Actemra, the company said. The median time to discharge for Actemra patients was 20 days, compared to 28 days for placebo patients. Genentech did say, however, that the difference cannot be considered statistically significant as the primary endpoint of the COVACTA study was not met.

Jul 29, 2020

Metal-breathing bacteria could transform electronics, biosensors, and more

Posted by in categories: biotech/medical, chemistry

When the Shewanella oneidensis bacterium “breathes” in certain metal and sulfur compounds anaerobically, the way an aerobic organism would process oxygen, it produces materials that could be used to enhance electronics, electrochemical energy storage, and drug-delivery devices.

The ability of this bacterium to produce molybdenum disulfide—a material that is able to transfer electrons easily, like graphene—is the focus of research published in Biointerphases by a team of engineers from Rensselaer Polytechnic Institute.

“This has some serious potential if we can understand this process and control aspects of how the bacteria are making these and other materials,” said Shayla Sawyer, an associate professor of electrical, computer, and systems engineering at Rensselaer.

Jul 29, 2020

Solving materials problems with a quantum computer

Posted by in categories: chemistry, engineering, information science, particle physics, quantum physics, supercomputing

Quantum computers have enormous potential for calculations using novel algorithms and involving amounts of data far beyond the capacity of today’s supercomputers. While such computers have been built, they are still in their infancy and have limited applicability for solving complex problems in materials science and chemistry. For example, they only permit the simulation of the properties of a few atoms for materials research.

Scientists at the U.S. Department of Energy’s (DOE) Argonne National Laboratory and the University of Chicago (UChicago) have developed a method paving the way to using quantum computers to simulate realistic molecules and complex materials, whose description requires hundreds of atoms.

The research team is led by Giulia Galli, director of the Midwest Integrated Center for Computational Materials (MICCoM), a group leader in Argonne’s Materials Science division and a member of the Center for Molecular Engineering at Argonne. Galli is also the Liew Family Professor of Electronic Structure and Simulations in the Pritzker School of Molecular Engineering and a Professor of Chemistry at UChicago. She worked on this project with assistant scientist Marco Govoni and graduate student He Ma, both part of Argonne’s Materials Science division and UChicago.

Jul 29, 2020

Yamaha YDX Moro unveiled as full suspension e-bike from the future

Posted by in categories: futurism, transportation

Yamaha has finally unveiled its new Yamaha YDX MORO electric mountain bike line. The new models feature Yamaha’s latest mid-drive e-bike motor and a brand new frame design unlike anything we’ve seen before.

Jul 29, 2020

Steps toward room-temperature superconductivity

Posted by in categories: materials, physics

The possibility of achieving room temperature superconductivity took a tiny step forward with a recent discovery by a team of Penn State physicists and materials scientists.

The surprising discovery involved layering a called molybdenum sulfide with another material called molybdenum carbide. Molybdenum carbide is a known superconductor—electrons can flow through the material without any resistance. Even the best of metals, such as silver or copper, lose energy through heat. This loss makes long-distance transmission of electricity more costly.

“Superconductivity occurs at very , close to absolute zero or 0 Kelvin,” said Mauricio Terrones, corresponding author on a paper in Proceedings of the National Academy of Sciences published this week. “The alpha phase of Moly carbide is superconducting at 4 Kelvin.”

Jul 29, 2020

The quantum Hall effect continues to reveal its secrets to mathematicians and physicists

Posted by in categories: mathematics, quantum physics

A transformative experiment is yielding fresh insights 40 years after the effect’s discovery — and energizing transdisciplinary collaborations.

Jul 29, 2020

Drug stimulation of neural stem cell repair leads to promising impact on treatment of childhood brain injury

Posted by in categories: biotech/medical, neuroscience

Through a cross-species study of metformin, a common drug used to treat Type 2 diabetes, a team of researchers and clinicians from the Donnelly Center and The Hospital for Sick Children (SickKids) has shown that it could one day be possible to repair brain injury using resident cells in the brain.

“No one’s actually shown before that you can take a drug where there’s a known mechanism on endogenous stem cells and demonstrate that it’s even possible to induce and positive recovery,” says Donald Mabbott, Program Head and Senior Scientist in the Neurosciences & Mental Health program at SickKids, and co-author of a study published in Nature Medicine on July 27.

Mabbott says metformin is a potential game-changer in terms of how childhood brain injury is treated.