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Dec 2, 2019

Cyrus, the Broad team up to make in vivo CRISPR use safer

Posted by in category: biotech/medical

Cyrus Biotechnology has teamed up with the Broad Institute to optimize CRISPR for use in humans. Feng Zhang, who had a hand in developing CRISPR, will serve as the Broad’s principal investigator for the collaboration.

One concern with using CRISPR-Cas9 to perform in vivo genome editing stems from the risk that the body will mount an immune response against the system. Those concerns have grown as researchers have shown that many people have antibodies against Cas9, reflecting the fact that the homologs of the protein used in genome editing systems are derived from bacteria that commonly infect people.

Cyrus, which lists Johnson & Johnson among its customers, thinks its technology can mitigate the risk of an immune reaction. That confidence reflects Cyrus’ experience of using software to identify and work around the epitopes in protein therapeutics that cause immunogenicity.

Dec 2, 2019

A vertical takeoff drone for life saving missions

Posted by in category: drones

An open-source stack is helping create practical drones for life-saving missions.

Dec 2, 2019

Europe’s Space Agency Joins Mission to Deflect Killer Asteroids

Posted by in category: space

The goal is to change the trajectory of a city-killer asteroid.


NASA and the ESA are going to try to reroute an asteroid.

Dec 2, 2019

How suspicions of spying threaten cross-border science

Posted by in categories: military, quantum physics, science

An intelligence startup warns that China is exploiting Western quantum scientists for military ends. The evidence is thin, but tensions are rising.

Dec 2, 2019

How to Get Solar Power on a Rainy Day? Beam It From Space

Posted by in category: space

A decades-old idea is finally getting a chance to shine—that is, a chance to send sunshine harvested by a satellite down to Earth.

Dec 2, 2019

Scientists: Ominous Black Hole Is Way Too Big to Exist

Posted by in category: cosmology

Black holes of such mass should not even exist in our Galaxy.


The black hole dubbed LB-1 is 15,000 light years from Earth.

Dec 2, 2019

Human behaviour follows probabilistic inference patterns

Posted by in category: futurism

How do human beings perceive their environment and take their decisions? To successfully interact with the immediate environment, for human beings it is not enough to have basic evidence of the world around them. This information by itself is insufficient because it is inherently ambiguous and requires integrating into a particular context to minimize the uncertainty of sensory perception. But, at the same time, the context is ambiguous. For example, am I in a safe or a dange…


According to a study published on Nov. 28 in Nature Communications by Philipp Schustek, Alexandre Hyafil and Rubén Moreno-Bote, researchers at the Center for Brain and Cognition of the Department of Information and Communication Technologies.

Universitat Pompeu Fabra — Barcelona

Dec 2, 2019

Scientists develop a pill that could reverse obesity and type 2 diabetes

Posted by in category: biotech/medical

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Dec 2, 2019

Oil-Eating Bacteria Could Help Clean Up Oil Spills

Posted by in category: sustainability

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Dec 2, 2019

Cross-linking of the Extracellular Matrix — Dr. William Bains

Posted by in categories: biotech/medical, life extension

The University of Cambridge’s Dr. William Bains provides a thorough overview of extracellular cross-links in this lecture. He explains that advanced glycation end-products (AGEs) can irreversibly link proteins together, and cross-linking AGEs appear to play an important role in aging. They are particularly problematic in the cardiovascular system, where cross-links cause our arteries to stiffen with age, raising blood pressure and making a patient more likely to suffer from a heart attack or stroke. Cross-links are also implicated in complications from diabetes. Dr. Bains explains the structure and nature of cross-links, where they accumulate in the body, and even what their surprising role is in cooking. He ends by discussing a major AGE-breaking drug that has been tested on humans and touches on potential future therapies.

Visit www.sens.org/videos to view the rest of our course lecture videos.