Lifeboat Foundation

A group of scientists announced a rare find Wednesday – the fossilized remains of a giant bug that crawled around Utah during the time of the dinosaurs.

Called “Morrisonnepa jurassica,” the insect roamed the region 151 million years ago and was discovered in the same geological formation as Allosaurus and Stegosaurus.

It appears to be related to modern giant water bugs, or Belostomatidae, which prey on fish, amphibians, snakes and invertebrates. The bugs are also known for their excruciating bite.

Gravitational-wave researchers at the University of Birmingham have developed a new model that promises to yield fresh insights into the structure and composition of neutron stars.

The model shows that vibrations, or oscillations, inside the stars can be directly measured from the gravitational-wave signal alone. This is because neutron stars will become deformed under the influence of tidal forces, causing them to oscillate at characteristic frequencies, and these encode unique information about the star in the gravitational-wave signal.

This makes asteroseismology — the study of stellar oscillations — with gravitational waves from colliding neutron stars a promising new tool to probe the elusive nature of extremely dense nuclear matter.

— Data remain sparse, but a few risks are emerging.

The average cost of stem cell treatment is $8,750.

I get asked many questions about stem cell therapies, but one of the most common over the years has been about the stem cell treatment cost. For instance, a reporter might ask, “How much does a stem cell treatment for MS cost?” and a patient might ask me, “How much is a fair cost for a stem cell therapy for arthritis?” Or, patients will voluntarily tell me what they paid or mention it in the comments. We hear various numbers thrown around about costs so I decided to do a poll on this. I even did an early update on the results of this poll, voicing my skepticism that the costs paid were worth it.

But the poll has gotten well over 500 responses now so I thought I would revisit it and what it might mean.

Continue reading “Update on stem cell treatment cost for 2018 from ongoing poll” »

Interesting articles on theranostic iron nanowires. I’m interested in watching all aspects of development of nanobots, because I think it may lead to new forms of treatments for superlongevity and superintelligence.

Phys.org: Iron nanorobots go undercover to do surveillance on living cells in real time:

https://phys.org/…/2020–05-iron-nanorobots-undercover-surve…

Continue reading “Magnetic core–shell nanowires as MRI contrast agents for cell tracking” »

Upon seeing the blood-stained gloves, O.J. Simpson may have had electrical activity in his brain that showed recognition, and guilt.

In 2015 Francesco Greco, head of the Laboratory of Applied Materials for Printed and Soft electronics (LAMPSe) at the Institute of Solid State Physics at Graz University of Technology, developed so-called “tattoo electrodes” together with Italian scientists.

These are conductive polymers that are printed using an inkjet printer on standard tattoo paper and then stuck to the skin like transfers to measure heart or muscle activity.

This type of electrode, optimized in 2018, opened up completely new paths in electrophysiological examinations, such as electrocardiography (ECG) or electromyography (EMG). Thanks to a thickness of 700 to 800 nanometres — that is about 100 times thinner than a human hair — the tattoos adapt to uneven skin and are hardly noticeable on the body.

The ability to modulate neural activity in specific brain circuits remotely and systematically could revolutionize studies of brain function and treatments of brain disorders. Sound waves of high frequencies (ultrasound) have shown promise in this respect, combining the ability to modulate neuronal activity with sharp spatial focus. Here, we show that the approach can have potent effects on choice behavior. Brief, low-intensity ultrasound pulses delivered noninvasively into specific brain regions of macaque monkeys influenced their decisions regarding which target to choose. The effects were substantial, leading to around a 2:1 bias in choices compared to the default balanced proportion. The effect presence and polarity was controlled by the specific target region. These results represent a critical step towards the ability to influence choice behavior noninvasively, enabling systematic investigations and treatments of brain circuits underlying disorders of choice.

Noninvasive and reversible modulation of neuronal activity in specific brain circuits may allow us to diagnose and treat brain disorders in, targeted ways. Low-intensity ultrasound, applied to the brain noninvasively, can be used to modulate neural activity with spatial specificity superior to other noninvasive methods such as transcranial electrical or magnetic stimulation (1–5). The neuromodulatory potential of ultrasound has been highlighted in studies that targeted peri-motor regions of anesthetized rodents or rabbits. Brief, low-intensity stimuli lead to observable movements of the limbs or other body parts (6–13).

However, the enthusiasm about the neuromodulatory potential of ultrasound has recently been dampened by studies that called these effects into question (14, 15). In addition, such overt effects have not been observed in large mammals including humans. Only small changes in neural signals (16–23) or small changes in reaction time or other metrics (24–26) have been found. Yet, to make it truly useful, the approach would ideally provide neuromodulatory effects that are strong enough to manifest in behavior. For example, if clinicians are to determine which brain circuits drive a patient’s craving for an addictive drug, the neuromodulatory effects on a particular neural circuit should be potent enough to yield measurable changes in the subject’s choice behavior, i.e., whether the subject decides to use the drug or not.

Revealing yet another super-power in the skillful squid, scientists have discovered that squid massively edit their own genetic instructions not only within the nucleus of their neurons, but also within the axon — the long, slender neural projections that transmit electrical impulses to other neurons. This is the first time that edits to genetic information have been observed outside of the nucleus of an animal cell.

The study, led by Isabel C. Vallecillo-Viejo and Joshua Rosenthal at the Marine Biological Laboratory (MBL), Woods Hole, is published this week in Nucleic Acids Research.