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Jun 5, 2023

Augmented reality needs an iPhone moment

Posted by in categories: augmented reality, virtual reality

‘This is the single greatest thing that could happen to this industry.’

As Apple prepares its long-rumored jump into augmented reality on Monday, doubts have shadowed every step of the way. There are reports of frequent changes in direction and skepticism inside Apple’s ranks. The device has allegedly been hard to manufacture and required numerous compromises. The process has taken years longer than Apple expected. And at a rumored $3,000, even Apple reportedly expects slow short-term sales.

But among AR professionals, the mood is jubilant. “This is the single greatest thing that could happen to this industry,” says Jay Wright, CEO of VR / AR collaboration platform Campfire 3D.

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Jun 5, 2023

Google’s AI-powered search experience is way too slow

Posted by in category: futurism

The worst thing about Google’s new AI-powered search experience is how long you have to wait. Can you think of the last time you waited for a Google Search result? For me, searches are generally instant. You type a thing in the search box, Google almost immediately spits out an answer to that thing, and then you can click some links to learn more about what you searched for or type something else into the box. It’s a virtuous, useful cycle that has turned Google Search into the most visited website in the world.

Google’s Search Generative Experience, on the other hand, has loading animations.

Let me back up a little.

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Jun 5, 2023

Philosophy & Literature on ‘Aristotle’s Paradox of Time’

Posted by in category: robotics/AI

Continued thoughts 💭 about humanity and our beloved AI

Maybe interesting.

173K likes, — Philosophy & Literature (@philosophyofexistence) on Instagram: ‘Aristotle’s Paradox of Time’

Jun 5, 2023

Vertical farms are growing more and more vegetables in urban areas

Posted by in category: sustainability

They don’t need soil or sunlight | Technology Quarterly.

Jun 5, 2023

Fluoridated water: Essential ingredient in U.S. water systems for cavity prevention and dental health equity

Posted by in categories: biotech/medical, health

Fluoridated water at recommended levels reduces dental cavities by 25%, emphasizing the importance of maintaining fluoride levels for effective caries prevention. Most water systems comply with safety standards, providing the full benefits of fluoridation.

Jun 5, 2023

Applications of single photons to quantum communication and computing

Posted by in categories: computing, quantum physics

This Review overviews the application of single photons in quantum communication and quantum computation discussing specific needs and requirements and achieved milestones and outlining future improvements.

Jun 5, 2023

EMP Balloon Attack Threat From Chinese Military

Posted by in categories: food, military, space

See the shocking reasons why near-space balloons are a perfect platform for a cheap effective hard to detect, hard to defeat asymmetric warfare means to deliver a stunning devastating EMP attack on the US mainland.

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Jun 4, 2023

PD-1 and PD-L1 Checkpoint Signaling Inhibition for Cancer Immunotherapy: Mechanism, Combinations, and Clinical Outcome

Posted by in categories: biotech/medical, evolution

Year 2017 PD-1 can eventually be used throughout the body to be used on all cancers which also naturally occurs in the body the common cancer drug Keytruda uses this type of targeting to destroy cancer cells.

Several cancers are highly refractory to conventional chemotherapy. The survival of tumors in several cases is assisted by checkpoint immunomodulation to maintain the imbalance between immune surveillance and cancer cell proliferation. Check point antibody inhibitors, such as anti-PD-1/PD-L1, are a novel class of inhibitors that function as a tumor suppressing factor via modulation of immune cell-tumor cell interaction. These checkpoint blockers are rapidly becoming a highly promising cancer therapeutic approach that yields remarkable antitumor responses with limited side effects. In recent times, more than four check point antibody inhibitors have been commercialized for targeting PD-1, PDL-1, and CTLA-4. Despite the huge success and efficacy of the anti-PD therapy response, it is limited to specific types of cancers, which attributes to the insufficient and heterogeneous expression of PD-1 in the tumor microenvironment. Herein, we review the current landscape of the PD-1/PD-L1 mechanistic role in tumor immune evasion and therapeutic outcome for cancer treatment. We also review the current progress in clinical trials, combination of drug therapy with immunotherapy, safety, and future of check point inhibitors for multiple types of cancer.

Immunotherapy is an exciting approach, and tremendous strides have recently been made in our perception of the role of the host immune response in affecting tumor growth and response to various therapies (Pardoll, 2012). Through these advances, novel immune check point inhibitors have been identified and cleared for use in the clinic (Figure 1). The evolution of immune checkpoint inhibitors as anticancer treatment options represents one of the most successful approach in cancer drug discovery in the past few years (Couzin-Frankel, 2013). Indeed, immune checkpoint inhibitors have emerged as a frontline treatment for multiple cancers, such as metastatic melanoma, non-small cell lung cancer (NSCLC), renal cell carcinoma (RCCs), and bladder or urothelial cancer. They are presently being assessed in numerous other cancer types, including breast cancer, head and neck cancer, and some advanced solid and hematological malignancies.

Jun 4, 2023

Five New Farming Technologies Tackle Climate-Change Threats

Posted by in categories: biotech/medical, food

Innovative ideas and devices are on the rise as heavier rainfall, harsher winters and disease-causing pests pose risks for agriculture.

Jun 4, 2023

New drug effective at preventing growth of lower-grade brain tumors, clinical trial finds

Posted by in categories: biotech/medical, neuroscience

A new drug that is in a phase 3 clinical trial has proven effective at preventing the growth of lower-grade brain tumors, with doctors saying nearly half of the patients in the trial haven’t needed chemotherapy or radiation years later. NBC News’ Lindsey Reiser has the details on the treatment.

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