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Jun 5, 2021

Inside the 1,300mph jet that will fly you from New York to London in less than four hours

Posted by in category: transportation

“The world’s first purchase agreement for net-zero carbon supersonic aircraft marks a significant step toward our mission to create a more accessible world,” said Boom CEO Blake Scholl in a statement.

The planes, which will fly twice the speed of current passenger jets, are expected to be rolled out in 2025, take flight in 2026, and start carrying passengers in 2029.

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Jun 5, 2021

Why NASA’s return to Venus could help save the Earth

Posted by in categories: futurism, space

The space agency is launching two missions to study Venus’ atmosphere and geological history.


“I did a lot of screaming and jumping up and down,” Grinspoon tells Inverse. “I scared my dog.”

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Jun 5, 2021

A catalyst that destroys perchlorate in water could clean Martian soil

Posted by in categories: biotech/medical, chemistry, robotics/AI, space travel

## JOURNAL OF THE AMERICAN CHEMICAL SOCIETY • JUN 4, 2021.

# *A lovely single step bio-inspired process with some interesting complex benefits particularly for humans on Mars.*

*by holly ober, university of california — riverside*

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Jun 5, 2021

Americans face mounting risk of hackers taking over brokerage accounts, regulators say

Posted by in category: cybercrime/malcode

It’s not just corporations that are facing an epidemic of cyber attacks — American retail investors are also struggling to contend with a surge in hackers taking over their investment accounts, regulators warn.

Jun 5, 2021

Artificial intelligence could help biologists classify the world’s tiny creatures

Posted by in categories: robotics/AI, sustainability

Automation could aid biodiversity monitoring.

Jun 5, 2021

Dozens of fish products recalled in 17 states because of Listeria concerns

Posted by in category: futurism

Banner Smoked Fish Inc. is recalling 43 of its s moked fish products in all package sizes, all package types and all lots, because of a potential Listeria monocytogenes contamination.

The problem was discovered through FDA routine inspection, and the products were found to be processed under unsanitary condition.

The recalled smoked fish were distributed through retail stores and also online in the New York, New Jersey, Illinois, Pennsylvania, California, Florida, Nebraska, Arizona, Massachusetts, Maryland, Virginia, Nevada, Oregon, Wisconsin, North Carolina, South Carolina and Georgia.

Jun 5, 2021

Antivirus software company Norton now allows mining ETH via pool service

Posted by in category: computing

Antivirus software company Norton has released a new crypto product that allows users to mine ether (ETH) from their personal computers.


NortonLifeLock, formerly Symantec Corporation, has released a new crypto product that allows users to mine ether (ETH) from their personal computers.

The product, Norton Crypto, is currently available to select customers who use the company’s antivirus software called Norton 360. The public launch of the product is expected “in the coming weeks.

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Jun 5, 2021

Dr. Matt Kaeberlein — Founder / Co-Director, Dog Aging Project — Professor, University of Washington

Posted by in categories: biotech/medical, life extension, neuroscience

Enrolling Tens Of Thousands Of Dogs, In 10-Year Study, To Unlock Healthy Aging Secrets — Dr Matt Kaeberlein, Founder / Co-Director, The Dog Aging Project, Professor, University of Washington, joins me on Progress, Potential, And Possibilities Nathan Shock Centers #Rapamycin #Dogs #Aging #Longevity #Healthspan #Geroscience.

#MitochondrialDisease

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Jun 5, 2021

Look: Here’s the best place for humans to live on Mars

Posted by in categories: Elon Musk, space

If space moguls like Elon Musk have their way, the red planet could one day be home to millions of people.


Arcadia Planitia, located in the northern hemisphere of the red planet, holds promise as a habitable, resource-rich area for space civilizations.

Jun 5, 2021

A Great Deal of Work Lies Ahead in the Development of In Vivo Reprogramming as a Therapy

Posted by in categories: bioengineering, biotech/medical, business, genetics, life extension, nuclear energy

The latest from Calico. A bit technical.


Reprogramming of ordinary somatic cells into induced pluripotent stem cells (iPSCs) was initially thought to be a way to obtain all of the patient matched cells needed for tissue engineering or cell therapies. A great deal of work has gone towards realizing that goal over the past fifteen years or so; the research community isn’t there yet, but meaningful progress has taken place. Of late, another line of work has emerged, in that it might be possible to use partial reprogramming as a basis for therapy, delivering reprogramming factors into animals and humans in order to improve tissue function, without turning large numbers of somatic cells into iPSCs and thus risking cancer or loss of tissue structure and function.

Reprogramming triggers some of the same mechanisms of rejuvenation that operate in the developing embryo, removing epigenetic marks characteristic of aged tissues, and restoring youthful mitochondrial function. It cannot do much for forms of damage such as mutations to nuclear DNA or buildup of resilient metabolic waste, but the present feeling is there is nonetheless enough of a potential benefit to make it worth developing this approach to treatments for aging. Some groups have shown that partial reprogramming — via transient expression of reprogramming factors — can reverse functional losses in cells from aged tissues without making those cells lose their differentiated type. But this is a complicated business. Tissues are made up of many cell types, all of which can need subtly different approaches to safe reprogramming.

Today’s open access preprint is illustrative of the amount of work that lies ahead when it comes to the exploration of in vivo reprogramming. Different cell types behave quite differently, will require different recipes and approaches to reprogramming, different times of exposure, and so forth. It makes it very hard to envisage a near term therapy that operates much like present day gene therapies, meaning one vector and one cargo, as most tissues are comprised of many different cell types all mixed in together. On the other hand, the evidence to date, including that in the paper here, suggests that there are ways to create the desired rejuvenation of epigenetic patterns and mitochondrial function without the risk of somatic cells dedifferentiating into stem cells.

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