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Aug 16, 2019

Inducing Pluripotency Through Multiple Routes

Posted by in categories: biotech/medical, genetics, life extension

A new study outlines multiple ways in which epiblast stem cells can be reprogrammed back into a fully pluripotent state, paving the way for a better understanding of epigenetics.

The role of epigenetics

Epigenetics are why our cells, which all have the same DNA, differ in function. A bone cell has the same genetics as a nerve cell, but its epigenetic switches instruct it to perform the functions of a bone cell and not a nerve cell. Epigenetic alterations, however, are one of the primary hallmarks of aging. As we age, harmful epigenetic switches are activated and beneficial ones are deactivated, causing age-related dysfunction. This may even lead to inflammation, which causes further epigenetic damage, leading to a dangerous feedback loop.

Aug 16, 2019

Ronald Kohanski, PhD

Posted by in categories: biological, life extension

Click on photo to start video.

Ronald Kohanski, PhD. is the Deputy Director of the Division of Aging Biology at the National Institute on Aging, and he gave the keynote for day two of our recent conference in New York City.

Aug 16, 2019

AI Startup Boom Raises Questions of Exaggerated Tech Savvy

Posted by in category: robotics/AI

Promise yields hype; hype yields false promises. says it uses artificial intelligence to help automate app-development. Current and former staffers say the company inflates its technical prowess to attract customers and investors.

Aug 16, 2019

Chinese space startup revs up for reusable rocket race

Posted by in category: satellites

LinkSpace’s test flight on Saturday came on the heels of a historic delivery of a satellite into orbit last month by privately owned Chinese firm iSpace.

BEIJING (Reuters) — Chinese startup LinkSpace on Saturday completed its third test of a reusable rocket in five months, stepping up the pace in China’s race to develop a technology key to cheap space launches in an expected global boom in satellite deployment.

Aug 15, 2019

Scientists discover new pain-sensing organ

Posted by in category: biotech/medical

A new organ involved in the sensation of pain has been discovered by scientists, raising hopes that it could lead to the development of new painkilling drugs.

Researchers say they have discovered that the special cells that surround the pain-sensing nerve cells that extend into the outer layer of skin appear to be involved in sensing pain – a discovery that points to a new organ behind the feeling of “ouch!”.

Aug 15, 2019

What if there was no big bang and we live in an ever-cycling universe?

Posted by in category: cosmology

There is no good evidence that our universe even had a beginning, a startling proposition that means the cosmos could collapse in about 100 billion years.

Aug 15, 2019

Swiss Scientists Upgrade CRISPR to Edit Many Genes at Once

Posted by in categories: bioengineering, biotech/medical, genetics

A research group at ETH Zurich, Switzerland, has made it possible to edit hundreds of genes at once with CRISPR gene editing.

CRISPR gene editing has revolutionized the biotech industry by providing an easy and quick way to genetically modify organisms. So far, however, CRISPR techniques have only managed to edit a maximum of seven genes at once. This limits the potential of the technique in creating cell therapies, since whole networks of genes need to be reprogrammed to control each cell’s fate.

The Swiss research group devised a way to overcome this limitation with a CRISPR technique able to edit 25 genes in one go. This number could also be increased to up to hundreds of genes at a time. This method therefore makes it possible to edit gene networks, and reprogram stem cells to become cell therapies such as skin cells or insulin-producing pancreatic cells.

Aug 15, 2019

MIT scholar Hillary Andales, ipaliliwanag kung bakit mahalaga ang Pinoy microsatellites

Posted by in category: alien life

Bago pa pirmahan ni Pangulong Rodrigo Duterte ang batas na bubuo sa isang national space agency, may Pinoy microsatellites nang lumilipad sa outer space. Ano kaya ang ginagawa nila sa kalawakan? Naghahanap ng aliens, black holes, o bagong planeta? Ipakikilala sa atin ni Hillary Andales sina Diwata 1 at Diwata 2, ang kauna-unahang Pinoy microsatellites.

Aug 15, 2019

Aubrey de Grey on how science will help us end aging and become almost immortal. Book Person #30

Posted by in categories: life extension, science

The de Grey… AEWR.

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Aug 15, 2019

CRISPR enters its first human clinical trials

Posted by in categories: biotech/medical, genetics

CUTTING ROOM Scientists will soon wield the molecular scissors CRISPR/Cas9 in the human body. Some people with a form of inherited blindness will have the gene editor injected into their eyes, where researchers hope it will snip out a mutation.