Lifeboat Foundation

Salk Institute scientists have harnessed stem cell technology to generate the first human insulin-producing pancreatic cell clusters that can evade the immune system. Generated from induced pluripotent stem cells (iPSCs), these “immune shielded” human islet-like organoids (HILOs) controlled blood glucose following transplantation into a mouse model of diabetes, without the use of immunosuppressive drugs. The researchers suggest the achievement represents a major advance in the quest for a safe and effective treatment for type 1 diabetes (T1D), which impacts an estimated 1.6 million people in the United States, at a cost of $14.4 billion annually.

“Most type 1 diabetics are children and teenagers,” said Salk professor Ronald Evans, PhD, holder of the March of Dimes chair in molecular and developmental biology. Evans is senior author of the team’s paper, which is published in Nature. “This is a disease that is historically hard to manage with drugs. We hope that regenerative medicine in combination with immune shielding can make a real difference in the field by replacing damaged cells with lab-generated human islet-like cell clusters that produce normal amounts of insulin on demand.”

Continue reading “Diabetes Controlled in Mice Using First Immune-Evading Human Islet Cell Organoids” »

The coronavirus has wreaked havoc on our world’s economy, and many scientists and nations are scrambling to get a vaccine out. In today’s video, I will talk about what will happen when that vaccine actually appears:

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Shalev Hulio wants to explain himself.

Normally, silence and secrecy are inherent in the spy business. For nine full years, Hulio never talked publicly about his billion-dollar hacking company—even when his hacking tools were linked to scandal or he was accused of being complicit in human rights abuses around the world. Lately, though, he’s speaking up.

“People don’t understand how intelligence works,” Hulio tells me over a video call from Tel Aviv. “It’s not easy. It’s not pleasant. Intelligence is a shitty business full of ethical dilemmas.”

Vastly extended life spans would bring dazzling opportunities — and daunting risks.

Black holes are at the center of almost all galaxies that have been studied so far. They have an unimaginably large mass and therefore attract matter, gas and even light. But they can also emit matter in the form of plasma jets—a kind of plasma beam that is ejected from the center of the galaxy with tremendous energy. A plasma jet can extend several hundred thousand light years far into space.

When this intense radiation is emitted, the black hole remains hidden because the light rays near it are strongly bent leading to the appearance of a shadow. This was recently reported by researchers of the Event Horizon Telescope (EHT) collaboration for the massive black hole in the giant ellipse galaxy M87.

In quasar 3C279—also a black hole—the EHT team found another phenomenon: At a distance of more than a thousand times the shadow of the black hole, the core of a plasma jet suddenly lit up. How the energy for this jet could get there as if through an invisible chimney was not yet known.

Known for eating other spiders, Portia is a genus of the jumping spider that is able to leap up to 50 times her own body length. Captured by stunning close up footage, we get to witness this amazing spider use its super powers to dine on prey three times her size.

Taken From The Hunt

Continue reading “Spider With Three Super Powers | The Hunt | BBC Earth” »

This raven acts just like a puppy every time he’s with his dad. He wants to play, share snacks, and even shakes his tail feathers!

For more of Loki the raven, you can check him out on Instagram: https://thedo.do/lokiraven, on YouTube: https://thedo.do/lokiravenyt, and on Facebook: https://www.facebook.com/lokitraven/.

Continue reading “Raven Shakes His Tail Feathers Every Time He Sees Dad | The Dodo” »

Untangling the origins of Beelzebufo — the giant frog that lived alongside the dinosaurs — turns out to be one of the most bedeviling problems in the history of amphibians.

Thank you to these paleoartists for allowing us to use their wonderful illustrations:
Ceri Thomas: http://alphynix.tumblr.com/
Nobu Tamura: https://spinops.blogspot.com/
Julio Lacerda: https://252mya.com/gallery/julio-lacerda

Continue reading “The Biggest Frog that Ever Lived” »

I have a NEW channel ► “Meet, Arnold!” — https://www.youtube.com/watch?v=NsoJa2pm6Mo

If you like this video — put Thumb Up button (please) and

Continue reading “What If Titanoboa Snake Didn’t Go Extinct?” »