Lifeboat Foundation

Malak Trabelsi Loeb

13-08-2020

Covid-19 did not only cause a health crisis around the world; It led to severe economic, social, and political challenges in various countries.

In response to the World Health Organization recommendations, governments imposed various precautionary measures in the course of managing its risks. Measures varied from mere social distancing to total lockdown and isolation in quarantine centers.

Continue reading “The Legal Industry and COVID-19 Challenges” »

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes severe respiratory tract infections in humans (COVID-19), has become a global health concern. Currently, several vaccine candidates against SARS-CoV-2 are in clinical trials but approval of these vaccines is likely to take a long time before they are available for public use. In a previous report, the importance of passive immunity and how immunoglobulin (Ig)G collected from recovered coronavirus patients could help in the protection against COVID-19 and boost the immune system of new patients was reported. Passive immunity by immunoglobulin transfer is a concept employed by most mammals and bovine IgG has a role to play in human therapy. IgG is one of the major components of the immunological activity found in cow’s milk and colostrum. Heterologous transfer of passive immunity associated with the consumption of bovine immune milk by humans has been investigated for decades for its immunological activity against infections. This short review focuses on passive immunity and how microfiltered raw immune milk or colostrum collected from cows vaccinated against SARS-CoV-2 could provide short-term protection against SARS-CoV-2 infection in humans and could be used as an option until a vaccine becomes commercially available.

Currently, different academic institutions and pharmaceutical companies worldwide have started programs to develop and test vaccine candidates against SARS-CoV-2 in clinical trials. An S-glycoprotein-based vaccine is a promising approach that has attracted the attention of scientists, since S-glycoprotein can be directly recognized by the host’s immune system. For the first coronavirus (SARS-CoV-1), which was identified in Guangdong province, China, in November 2002, different vaccines were developed and tested in animal models. Some of these vaccines prevented animal infection after challenge with SARS-CoV-1. Kapadia et al. showed that neutralizing antibodies against SARS-CoV-1 could be detected in sera from mice immunized with S-glycoprotein of SARS-CoV-1 (10, 11).

https://youtube.com/watch?v=EXtkq07oUaM

Everybody has questions about space and what’s beyond the horizon. Our mission is to be the answer.

Welcome to the United States Air Force. Learn about great opportunities for enlisted airmen, officers and health care professionals.

The proposed mechanism of action described in the claim that 5G millimeter waves can generate SARS-CoV-2 in human cells violates fundamental principles of biology. Scientific evidence does not support a causal relationship between 5G and COVID-19. Many of the regions with the highest COVID-19 infection rates, such as Brazil, do not have 5G coverage, providing further evidence that 5G is not associated with the pandemic.

FULL CLAIM: 5G generates coronavirus in human skin cells

Scientists from 4 different Swiss universities describe how adhesion molecules activate autoaggressive immune cells and drive their infiltration in the nervous system in a model of multiple sclerosis.

Click to read the paper published in Frontiers in Immunology: https://fro.ntiers.in/tp1U

In experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), myelin-specific T cells are activated in the periphery and differentiate in T helper (Th) 1 and Th17 effector cells, which cross the blood-brain barrier (BBB) to reach the central nervous system (CNS), where they induce neuroinflammation. Here, we explored the role of intercellular adhesion molecule-1 (ICAM-1) and ICAM-2 in the activation of naïve myelin-specific T cells and in the subsequent migration of differentiated encephalitogenic Th1 and Th17 cells across the BBB in vitro and in vivo. While on antigen-presenting cells ICAM-1, but not ICAM-2 was required for the activation of naïve CD4⁺ T cells, endothelial ICAM-1 and ICAM-2 mediated both Th1 and Th17 cell migration across the BBB. ICAM-1/-2-deficient mice developed ameliorated typical and atypical EAE transferred by encephalitogenic Th1 and Th17 cells, respectively. Our study underscores important yet cell-specific contributions for ICAM-1 and ICAM-2 in EAE pathogenesis.

Continue reading “Intercellular Adhesion Molecule-1 (ICAM-1) and ICAM-2 Differentially Contribute to Peripheral Activation and CNS Entry of Autoaggressive Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis” »

France is deploying two Rafale fighter jets and a naval frigate in the eastern Mediterranean because of tensions between Greece and Turkey.

French President Emmanuel Macron has urged Turkey to halt oil and gas exploration in disputed waters in the area. A Turkish survey ship began such a mission on Monday, angering Greece.

Mr Macron told Greek Prime Minister Kyriakos Mitsotakis that the French military would monitor the situation.

The UK, US and Canada say state-backed hackers tried to steal coronavirus vaccine research.

A global research team has been able to transform brackish water and seawater into safe, clean drinking water in less than 30 minutes using metal-organic frameworks (MOFs) and sunlight.

In a discovery that could provide potable water for millions of people across the world, researchers were not only able to filter harmful particles from water and generate 139.5L of clean water per kilogram of MOF per day, but also perform this task in a more energy-efficient manner than current desalination practices.

The World Health Organization suggests good quality drinking water should have a total dissolved solid (TDS) of 600 parts per million (ppm). Researchers were able to achieve a TDS of 500 ppm in just 30 minutes and regenerate the MOF for reuse in four minutes under sunlight.

Fired brick is a universal building material, produced by thousand-year-old technology, that throughout history has seldom served any other purpose. Here, we develop a scalable, cost-effective and versatile chemical synthesis using a fired brick to control oxidative radical polymerization and deposition of a nanofibrillar coating of the conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT). A fired brick’s open microstructure, mechanical robustness and ~8 wt% α-Fe₂O₃ content afford an ideal substrate for developing electrochemical PEDOT electrodes and stationary supercapacitors that readily stack into modules. Five-minute epoxy serves as a waterproof case enabling the operation of our supercapacitors while submerged underwater and a gel electrolyte extends cycling stability to 10,000 cycles with ~90% capacitance retention.