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Nov 10, 2020

Researchers model source of eruption on Jupiter’s moon Europa

Posted by in category: alien life

On Jupiter’s icy moon Europa, powerful eruptions may spew into space, raising questions among hopeful astrobiologists on Earth: What would blast out from miles-high plumes? Could they contain signs of extraterrestrial life? And where in Europa would they originate? A new explanation now points to a source closer to the frozen surface than might be expected.

Rather than originating from deep within Europa’s oceans, some eruptions may originate from water pockets embedded in the icy shell itself, according to new evidence from researchers at Stanford University, the University of Arizona, the University of Texas and NASA’s Jet Propulsion Laboratory.

Using images collected by the NASA spacecraft Galileo, the researchers developed a model to explain how a combination of freezing and pressurization could lead to a cryovolcanic eruption, or a burst of water. The results, published Nov. 10 in Geophysical Research Letters, have implications for the habitability of Europa’s underlying ocean—and may explain eruptions on other icy bodies in the solar system.

Nov 10, 2020

The fight over the internet, under the sea | CNBC Explains

Posted by in category: internet

The ocean is home to more than 700,000 miles of submarine cables that carry the internet worldwide. This crucial infrastructure is at the center of a development race between the big tech companies amidst geopolitical rivalries between the world’s most powerful nations. CNBC’s Tom Chitty explains.

Continue reading “The fight over the internet, under the sea | CNBC Explains” »

Nov 10, 2020

Magnetic FreeBOT balls make giant leap for robotics

Posted by in category: robotics/AI

A unique type of modular self-reconfiguring robotic system has been unveiled. The term is a mouthful, but it basically refers to a robotic enterprise that can construct itself out of modules that connect to one another to achieve a certain task.

There has been great interest in such machines, also referred to as MSRRs, in recent years. One recent project called simply Space Engine can construct its own physical space environment to meet living, work and recreational needs. It accomplishes those tasks by generating its own kinetic forces to move and shape such spaces. It does this through adding and removing electromagnets to shift and construct modules into optimum room shapes.

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Nov 10, 2020

Strange Images Captured By NASA That Need Explaining

Posted by in category: space

Nov 10, 2020

Kosta Tsipis, MIT physicist and prominent voice for nuclear disarmament, dies at 86

Posted by in categories: existential risks, military, nuclear weapons, physics, treaties

In arguing against nuclear war, Dr. Tsipis said he came « to believe that reason must prevail. »


A curious boy who gazed at the stars from his mountainside Greek village and wondered how the universe came to be, Kosta Tsipis was only 11 when news arrived that the first atomic weapon had been dropped on Hiroshima, Japan.

“After the bomb went off, I sent away for a book because I wanted to understand it,” he told the Globe in 1987.

Continue reading “Kosta Tsipis, MIT physicist and prominent voice for nuclear disarmament, dies at 86” »

Nov 10, 2020

Two genes regulate social dominance

Posted by in categories: biotech/medical, chemistry

Rank in social hierarchy is a condition not solely claimed by humans. In the animal kingdom, male peacocks exhibit brightly colored plumes to illustrate dominance, and underwater, male fish show pops of bright colors to do the same. Despite the links identified between social status, physiology and behavior, the molecular basis of social status has not been known, until now.

“We discovered that two paralogous androgen receptor genes control social status in African cichlid fish,” reports Beau Alward in the Proceedings of the National Academy of Sciences. Alward is an assistant professor of psychology at the University of Houston with a joint appointment in biology and biochemistry. Paralogs are duplicate genes; androgens are hormones like testosterone necessary for male sexual development.

“Testosterone binds to to exert its effects. What we found through genome editing is that the two genes encoding these receptors are required for different aspects of social status,” said Alward. “This type of coordination of social status may be fundamental across species that rely on social information to optimally guide physiology and behavior.”

Nov 10, 2020

Four Quick Stories on Press Freedoms and Venture Funding: Age of Ingenuity

Posted by in categories: biotech/medical, government, military

https://www.youtube.com/watch?v=wb7o_9CUmiM&feature=youtu.be

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Sources cited in this episode include the following:

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Nov 10, 2020

Genetic disposition protects immune system from aging

Posted by in categories: biotech/medical, genetics, life extension

A genetic disposition that plays a role in the development of the heart in the embryo also appears to play a key role in the human immune system. This is shown by a recent study led by the University of Bonn (Germany). When the gene is not active enough, the immune defense system undergoes characteristic changes, causing it to lose its effectiveness. Doctors speak of an aging immune system, as a similar effect can often be observed in older people. In the medium term, the results may contribute to reduce these age-related losses. The study is published in the journal Nature Immunology.

The gene with the cryptic abbreviation CRELD1 has so far been a mystery to science. It was known to play an important role in the development of the heart in the embryo. However, CRELD1 remains active after birth: Studies show that it is regularly produced in practically all of the body. For what purpose, however, was previously completely unknown.

The Bonn researchers used a novel approach to answer this question. Nowadays, scientific studies with often include so-called transcriptome analyses. By these means, one can determine which genes are active to what extent in the respective test subjects. Researchers are also increasingly making the data they obtain available to colleagues, who can then use it to work on completely different matters. “And this is exactly what we did in our study,” says Dr. Anna Aschenbrenner from the LIMES Institute at the University of Bonn and member of the ImmunoSensation² Cluster of Excellence.

Nov 10, 2020

Fungal diversity in deep-sea extreme environments

Posted by in category: futurism

The deep-sea is one of the most mysterious and unexplored extreme environments, holding great potential and interest for science. Despite extensive studies on deep-sea prokaryotes, the diversity of fungi, one of the most ecologically important groups of eukaryotic micro-organisms, remains largely unknown. However, the presence of fungi in these ecosystems is starting to be recognised. Many fungi have been isolated by culture-dependent methods from various deep-sea environments, with the majority showing similarity to terrestrial species. However, culture-independent methods have revealed many novel fungal phylotypes, including novel fungal lineages recently described as Cryptomycota, which are suspected to lack typical fungal chitin-rich cell walls. Although true fungal diversity and its role in deep-sea environments is still unclear, the intention of this review is to assess current knowledge of the diversity of fungi in these ecosystems and to suggest future direction for deep-sea fungal research.

Nov 10, 2020

Marine Fungi: A Source of Potential Anticancer Compounds

Posted by in categories: biotech/medical, chemistry

Metabolites from marine fungi have hogged the limelight in drug discovery because of their promise as therapeutic agents. A number of metabolites related to marine fungi have been discovered from various sources which are known to possess a range of activities as antibacterial, antiviral and anticancer agents. Although, over a thousand marine fungi based metabolites have already been reported, none of them have reached the market yet which could partly be related to non-comprehensive screening approaches and lack of sustained lead optimization. The origin of these marine fungal metabolites is varied as their habitats have been reported from various sources such as sponge, algae, mangrove derived fungi, and fungi from bottom sediments. The importance of these natural compounds is based on their cytotoxicity and related activities that emanate from the diversity in their chemical structures and functional groups present on them. This review covers the majority of anticancer compounds isolated from marine fungi during 2012–2016 against specific cancer cell lines.

Marine fungi are important source of secondary metabolites useful for the drug discovery purposes. Even though marine fungi are less explored in comparison to their terrestrial counterparts, a number of useful hits have been obtained from the drug discovery perspective adding to their importance in the natural product discovery (Molinski et al., 2009; Butler et al., 2014), which have yielded a wide range of chemically diverse agents with antibacterial, antiviral and anticancer properties in animal systems. Starting with the celebrated example of cephalosporins, marine fungi have provided unique chemical skeletons that could be used to develop drugs of clinical importance (Bhadury et al., 2006; Saleem et al., 2007; Javed et al., 2011; Sithranga and Kathiresan, 2011). Fungi, in general, have been generous source of drugs as evidenced by the isolation of many drugs in use such as paclitaxel, camptothecin, vincristine, torreyanic acid and cytarabine to name a few.