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The South Pole neutrino detector saw a Glashow resonance event, a phenomenon predicted by Nobel laureate physicist Sheldon Glashow in 1960 where an electron antineutrino and an electron interact to produce a W-boson.

On December 62016, a high-energy particle called an electron antineutrino hurtled to Earth from outer space at close to the speed of light carrying 6.3 petaelectronvolts (PeV) of energy. Deep inside the ice sheet at the South Pole, it smashed into an electron and produced a particle that quickly decayed into a shower of secondary particles. The interaction was captured by a massive telescope buried in the Antarctic glacier, the IceCube Neutrino Observatory.

The Fort Worth-based company claims to be the first helicopter manufacturer to present at CES.

In the new study, researchers instead aimed to reduce the amount of Nav1.7 that cells make in the first place. Bioengineer Ana Moreno and her colleagues at the University of California, San Diego, modified the “molecular scissors” of the gene editor CRISPR. Changes to the cutting enzyme Cas9 caused it to bind to DNA that makes Nav1.7 without slicing it, effectively preventing the Nav1.7 protein from being made. The researchers enhanced this silencing effect by hitching Cas9 to a repressor, another protein that inhibits gene expression.

The researchers tested the Cas9 approach—and a similar approach using another gene-editing protein known as a zinc finger—in mice given the chemotherapy drug paclitaxel, which can cause chronic nerve pain in cancer patients. The team measured pain by poking the animals’ paws with a thin nylon filament. Paclitaxel prompted mice to withdraw from gentler pokes, indicating that a normally nonpainful stimulus had become painful. But 1 month after an injection of the gene-silencing treatment into their spinal fluid, rodents responded much like mice that had never gotten paclitaxel, whereas untreated rodents remained hypersensitive, the team reports today in.

The approach could also prevent pain when given before paw injections of either the inflammation-causing compound carrageenan or a molecule called BzATP that increases pain sensitivity. And treated mice behaved no differently from untreated ones when their opposite paw—not inflamed by carrageenan—was exposed to a hot surface. That’s an encouraging initial sign that the injection didn’t silence Nav1.7 so completely that it creates a dangerous numbness to all pain, Moreno says. Behavioral tests so far haven’t turned up evidence of potentially concerning side effects; the injections didn’t appear to alter the animals’ movement, cognition, or anxiety levels.

Geoscientists at Sandia National Laboratories used 3D-printed rocks and an advanced, large-scale computer model of past earthquakes to understand and prevent earthquakes triggered by energy exploration.

Injecting water underground after unconventional oil and gas extraction, commonly known as fracking, geothermal energy stimulation and carbon dioxide sequestration all can trigger earthquakes. Of course, energy companies do their due diligence to check for faults—breaks in the earth’s upper crust that are prone to earthquakes—but sometimes earthquakes, even swarms of earthquakes, strike unexpectedly.

Continue reading “Scientists use 3D-printed rocks, machine learning to detect unexpected earthquakes” »

Spurred on by quantum experiments that scramble the ordering of causes and their effects, some physicists are figuring out how to abandon causality altogether.

TOWARDS a METAMATERIALLY-BASED ANALOGUE SENSOR FOR TELESCOPE EYEPIECES jeremy batterson.

https://www.youtube.com/watch?v=rVQWmWkbzkw.

(NB: Those familiar with photography or telescopy can skip over the “elements of a system,” since they will already know this.)

Continue reading “Navy engineer devises new way to enhance night vision for ground forces” »

Summary: Study identified 300 “hub genes” that appear to control separate gene networks in brain tissue samples. The SAMD3 gene appears to be a master regulator to control the activity of many of the gene hubs and the genes the hubs control.

Source: UT Southwestern Medical Center.

UT Southwestern scientists have identified key genes involved in brain waves that are pivotal for encoding memories. The findings, published online this week in Nature Neuroscience, could eventually be used to develop novel therapies for people with memory loss disorders such as Alzheimer’s disease and other forms of dementia.

Researchers have developed a new data transfer system that is 20 times faster than USB 3.0.

This combines high-frequency silicon chips with a polymer cable as thin as a strand of hair. The system could boost energy efficiency in data centres and lighten the loads of electronics-rich spacecraft. Researchers presented their breakthrough at the recent IEEE International Solid-State Circuits Conference, held virtually.

“There’s an explosion in the amount of information being shared between computer chips – cloud computing, the Internet, big data. And a lot of this happens over conventional copper wire,” says Jack Holloway, who led the research. Holloway completed his PhD in MIT’s Department of Electrical Engineering and Computer Science last year and currently works for Raytheon.

It was the 6th launch and landing for this Falcon 9 first stage.

A SpaceX Falcon 9 rocket launched a new batch of 60 Starlink internet satellites to orbit early this morning (March 11) and nailed its landing on a floating platform at sea.