Lifeboat Foundation

Common medications can accumulate in gut bacteria, a new study has found, altering bacterial function and potentially reducing the effectiveness of the drug. These interactions—seen for a variety of medications, such as depression, diabetes, and asthma drugs—could help researchers to better understand individual differences in drug effectiveness and side-effects, according to the study published in Nature.

It is known that bacteria can chemically modify some drugs, a process known as biotransformation. This study, led by researchers from the Medical Research Council (MRC) Toxicology Unit at the University of Cambridge and the European Molecular Biology Laboratory (EMBL) in Germany, is the first to show that certain species of gut bacteria accumulate human drugs, altering the types of bacteria and their activity.

This could change the effectiveness of the drug both directly, as the accumulation could reduce the availability of the drug to the body, and indirectly, as altered bacterial function and composition could be linked to side-effects.

An NYU-based research team created microscopic cells out of a polymer that can do active transport, a process all living cells do that is difficult to replicate.

All the way back in the 1940s, in Switzerland, work was underway on a breakthrough Bus that would be pure electric, and not need batteries. Introducing the Gyro-bus, a innovative look at storing energy in a flywheel! Mechanical Energy storage baby, and we’re doing a deep dive this week on Two Bit da Vinci!

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Continue reading “This Insane Bus Was Pure ELECTRIC & Didn’t Need Batteries” »

Fri, Dec 17 at 6 PM PST.

Targeted Ariane 5 launch date for James Webb Space Telescope.

- Ariane 5 Flight VA256 launching the James Webb Space Telescope (Webb) is scheduled for December 18 2021, from the Guiana Space Center.

Continue reading “Arianespace — Ariane 5 — VA256 James Webb Telescope — Guiana Space Center — Space Affairs Livestream” »

Amazon took aim at Elon Musk in its latest filing in a series of tiffs with SpaceX over its plans to expand Starlink.

Youthereum talking about rejuvenation, funding, there is a history lesson here but the modern look starts at 38:01.

My overview of the history of partial reprogramming — a novel approach to epigenetic rejuvenation that uses short bursts of Yamanaka factors expression to periodically roll back the epigenetic state of cells to a younger pattern.

The test was meant to simulate the impacts of being on a speed boat during high seas, an experience that can involve a ton of harsh G forces.

The device has its limits, however, particularly when it’s not used for its intended purpose. While technologically impressive, the Forge brace didn’t allow Rose to dunk a basketball, as he found out to his dismay.

Continue reading “Watch a Guy With Bad Knees Get Superpowers With a Powered Exoskeleton” »

Physicists sifting through old particle accelerator data have found evidence of a highly-elusive, never-before-seen process: a so-called triangle singularity.

First envisioned by Russian physicist Lev Landau in the 1950s, a triangle singularity refers to a rare subatomic process where particles exchange identities before flying away from each other. In this scenario, two particles — called kaons — form two corners of the triangle, while the particles they swap form the third point on the triangle.

Black holes are regions of space-time with huge amounts of gravity. Scientists originally thought that nothing could escape the boundaries of these massive objects, including light.

The precise nature of black holes has been challenged ever since Albert Einstein’s general theory of relativity gave rise to the possibility of their existence. Among the most famous findings was English physicist Stephen Hawking’s prediction that some particles are actually emitted at the edge of a black hole.

Physicists have also explored the workings of vacuums. In the early 1970s, as Hawking was describing how light can escape a black hole’s gravitational pull, Canadian physicist William Unruh proposed that a photodetector accelerated fast enough could “see” light in a vacuum.