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Scientists also analysed microbial genetic material from the stool of men with prostate cancer and identified a specific bacterium – Ruminococcus – that may play a major role in the development of resistance. In contrast, the bacterium Prevotella stercorea was associated with favourable clinical outcomes.

Image: Section of a mouse gut. Credit: Kevin Mackenzie, University of Aberdeen.

Common gut bacteria can fuel the growth of prostate cancers and allow them to evade the effects of treatment, a new study finds.

Continue reading “‘Gut bugs’ can drive prostate cancer growth and treatment resistance” »

Tesla Giga Shanghai has officially exceeded the Fremont Factory’s output, according to Elon Musk’s calculations. As Tesla’s main export hub, Giga Shanghai’s output will play a significant role in the company’s global growth.

“We have three new factories. Giga Shanghai has done an incredible job. And Giga Shanghai now exceeds Fremont in production,” Musk announced at the 2021 Annual Shareholders Meeting.

Musk pointed out that Tesla Giga Shanghai took roughly 11 months to build and reached full volume production a year later. Since Giga Shanghai started operations, Tesla’s production and delivery numbers have noticeably increased.

Specialized cells that conduct electricity to keep the heart beating have a previously unrecognized ability to regenerate in the days after birth, a new study in mice by UT Southwestern researchers suggests. The finding, published online in the Journal of Clinical Investigation, could eventually lead to treatments for heart rhythm disorders that avoid the need for invasive pacemakers or drugs by instead encouraging the heart to heal itself.

“Patients with arrhythmias don’t have a lot of great options,” said study leader Nikhil V. Munshi, M.D., Ph.D., a cardiologist and Associate Professor of Internal Medicine, Molecular Biology, and in the Eugene McDermott Center for Human Growth and Development. “Our findings suggest that someday we may be able to elicit regeneration from the heart itself to treat these conditions.”

Dr. Munshi studies the cardiac conduction system, an interconnected system of specialized heart muscle cells that generate electrical impulses and transmit these impulses to make the heart beat. Although studies have shown that nonconducting heart muscle cells have some regenerative capacity for a limited time after birth—with many discoveries in this field led by UTSW scientists—conducting cells called nodal cells were largely thought to lose this ability during the fetal period.

Okay…very odd indeed.

As already mentioned, the Saudi Arabian Government officially granted Sophia citizenship in 2017. She is the first and only robot to be an official citizen of a country. Her citizenship sparked some controversy, and not just from people who don’t think robots deserve rights. Rather, many people pointed out the contrast to women’s rights in the country.

Continue reading “World’s First Robot Citizen Sophia Said She Wants To Have A Baby” »

Exclusive: Report from planning exercise in 2016 alerted government of need to stockpile PPE and set up contact tracing system.

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It probably didn’t feel like much, but that simple kind of motion required the concerted effort of millions of different neurons in several regions of your brain, followed by signals sent at 200 mph from your brain to your spinal cord and then to the muscles that contracted to move your arm.

At the cellular level, that quick motion is a highly complicated process and, like most things that involve the human brain, scientists don’t fully understand how it all comes together.

Continue reading “An ultra detailed map of the brain region that controls movement, from mice to monkeys to humans” »

Not all private space players make as much noise as Musk, Bezos, and Branson.

It may get less coverage than SpaceX and Virgin Galactic, but Space Adventures has helped a huge number of people get to space.

A new method – which has been dubbed “light beads microscopy” – is described in the journal Nature. This offers a creative solution that pushes the limits of imaging speed and is limited only by the physical nature of fluorescence itself. It eliminates the “deadtime” between sequential laser pulses when no neuroactivity is recorded and at the same time the need for scanning.

The technique breaks one strong pulse into 30 smaller sub-pulses, each at a different strength, which dive into 30 different depths of scattering but induce the same amount of fluorescence at each depth. This is accomplished with a cavity of mirrors that staggers the firing of each pulse in time and ensures that they can all reach their target depths via a single microscope focusing lens. Using this approach, the only limit to the rate at which samples can be recorded is the time it takes the fluorescent tags to flare. That means broad swathes of the brain can be recorded within the same time it would take a conventional two-photon microscope to capture a much smaller network of brain cells.

Scientists at Rockefeller University, New York, integrated their new system into a microscopy platform with access to a large brain volume. This enabled the recording of activity in more than a million neurons across the entire cortex of a mouse brain for the first time.