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Dec 2, 2022

Breaching the Blood–Brain Tumor Barrier for Tumor Therapy

Posted by in categories: biotech/medical, neuroscience

Tumors affecting the central nervous system (CNS), either primary or secondary, are highly prevalent and represent an unmet medical need. Prognosis of these tumors remains poor, mostly due to the low intrinsic chemo/radio-sensitivity of tumor cells, a meagerly known role of the microenvironment and the poor CNS bioavailability of most used anti-cancer agents. The BBTB is the main obstacle for anticancer drugs to achieve therapeutic concentrations in the tumor tissues. During the last decades, many efforts have been devoted to the identification of modalities allowing to increase drug delivery into brain tumors. Until recently, success has been modest, as few of these approaches reached clinical testing and even less gained regulatory approval.

Dec 2, 2022

Quantum Steering That’s Robust to Loss and Noise

Posted by in categories: quantum physics, security

Researchers demonstrate a loss-tolerant method for so-called quantum steering, a phenomenon that could give quantum communication networks complete security.

Dec 2, 2022

Dark Matter Could Cause Excess Optical Background

Posted by in categories: cosmology, evolution, particle physics

Axions that decay into photons could account for visible light that exceeds what’s expected to come from all known galaxies.

If you could switch off the Milky Way’s stars and gaze at the sky with a powerful telescope, you’d see the cosmic optical background (COB)—visible-wavelength light emitted by everything outside our Galaxy. Recent studies by the New Horizons spacecraft—which, after its Pluto flyby, has been looking further afield—have returned the most precise measurements of the COB yet, showing it to be brighter than expected by a factor of 2. José Bernal and his colleagues at Johns Hopkins University in Maryland propose that this excess could be caused by decaying dark matter particles called axions [1]. They say that their model could be falsified or supported by future observations.

Comparing COB measurements to predictions provides a tool for testing hypotheses about the structure of the Universe. But measuring the COB is very difficult due to contamination by diffuse light from much nearer sources, especially sunlight scattered by interplanetary dust. Observing from the edge of our Solar System, New Horizons should be unaffected by most of this contamination, making the measured excess brightness a tool for improving our understanding of galaxy evolution.

Dec 2, 2022

Intelligent Materials: Science Fiction to Science Fact

Posted by in categories: robotics/AI, transportation

Materials that learn to change their shape in response to an external stimulus are a step closer to reality, thanks to a prototype system produced by engineers at UCLA.

Living entities constantly learn, adapting their behaviors to the environment so that they can thrive regardless of their surroundings. Inanimate materials typically don’t learn, except in science fiction movies. Now a team led by Jonathan Hopkins of the University of California, Los Angeles (UCLA), has demonstrated a so-called architected material that is capable of learning [1]. The material, which is made up of a network of beam-like components, learns to adapt its structure in response to a stimulus so that it can take on a specific shape. The team says that the material could act as a model system for future “intelligent” manufacturing.

The material developed by Hopkins and colleagues is a so-called mechanical neural network (MNN). If produced on a commercial scale, scientists think that these intelligent materials could revolutionize manufacturing in fields from building construction to fashion design. For example, an aircraft wing made from a MNN could learn to morph its shape in response to a change in wind conditions to maintain the aircraft’s flying efficiency; a house made from a MNN could adjust its structure to maintain the building’s integrity during an earthquake; and a shirt weaved from a MNN could alter its pattern so that it fits a person of any size.

Dec 2, 2022

Synchronized Neural Oscillations in the Right Brain Induce Empathic Behavior

Posted by in category: neuroscience

Summary: Empathy is induced by synchronized neural oscillations in the right hemisphere of the brain, a new mouse study reveals.

Source: Institute for Basic Science.

A research team led by Dr. SHIN Hee-Sup at the Center for Cognition and Sociality (CCS) within the Institute for Basic Science (IBS) in Daejeon, South Korea has discovered the underlying neural mechanism that allows us to feel empathy.

Dec 2, 2022

Scientists Just Revealed That Advanced Civilizations Could Be Doing This To Black Holes

Posted by in category: cosmology

https://www.youtube.com/watch?v=UT07QaPDxos

Dec 2, 2022

Julian Barbour on “The Janus Point: A New Theory of Time” | Closer To Truth Chats

Posted by in category: quantum physics

Physicist Julian Barbour discusses his newest book, “The Janus Point: A New Theory of Time.” In it, Barbour makes the radical argument that the growth of order drives the passage of time — and shapes the destiny of the universe.

Read “The Janus Point”: https://www.basicbooks.com/titles/julian-barbour/the-janus-point/9780465095469/
Julian Barbour’s Website: http://www.platonia.com/

Continue reading “Julian Barbour on ‘The Janus Point: A New Theory of Time’ | Closer To Truth Chats” »

Dec 2, 2022

Episodes: Science goes to the movies

Posted by in category: science

Share your videos with friends, family, and the world.

Dec 2, 2022

Scientists Spot Black Hole Energy Beam as Bright as 1,000 Trillion Suns Pointed at Earth

Posted by in categories: cosmology, particle physics

So-called relativistic jets of energetic particles are stunning, destructive spectacles, and this one was “unprecedented.”

Dec 2, 2022

How touch dampens the brain’s response to painful stimuli

Posted by in category: neuroscience

When we press our temples to soothe an aching head or rub an elbow after an unexpected blow, it often brings some relief. It is believed that pain-responsive cells in the brain quiet down when these neurons also receive touch inputs, say scientists at MIT’s McGovern Institute for Brain Research, who for the first time have watched this phenomenon play out in the brains of mice.

The team’s discovery, reported Nov. 6 in the journal Science Advances, offers researchers a deeper understanding of the complicated relationship between pain and touch and could offer some insights into chronic pain in humans.

“We’re interested in this because it’s a common human experience,” says McGovern investigator Fan Wang. “When some part of your body hurts, you rub it, right? We know touch can alleviate pain in this way.” But, she says, the phenomenon has been very difficult for neuroscientists to study.