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May 6, 2024
New influenza vaccine strategies aim to enhance protection with T-cell responses
Posted by Shubham Ghosh Roy in categories: biotech/medical, finance
In a recent review published in the journal Nature Reviews Immunology, researchers discussed the limitations of current influenza vaccines and the potential for future vaccines to induce both T-cell responses and antibodies for enhanced protection. They examined the strategies to develop influenza vaccines with broad strain specificity and long-term efficacy, covering protection requirements, immune response evaluation, expected outcomes, and financial considerations.
Study: Opportunities and challenges for T cell-based influenza vaccines. Image Credit: CI Photos / Shutterstock.
May 5, 2024
World’s Biggest Neuromorphic Computer Can Run Deep Learning
Posted by Cecile G. Tamura in category: robotics/AI
Hala Point will be the first large-scale neuromorphic system to run both SNNs and sparse feedforward DNNs like those used in mainstream branches of AI today (though conversion of DNNs and retraining are required).
Hala Point, a new Intel Loihi-based computer at Sandia National Labs, is a 6U system drawing about 2.6 kW.
May 5, 2024
NVIDIA CEO Jensen Huang Discloses The Company’s “Secret Sauce”, Says He Still Serves Dishes The Best
Posted by Genevieve Klien in category: futurism
It sometimes feels like NVIDIA was destined to be in the position it currently is, and CEO Jensen Huang has highlighted the company’s “secret sauce” in an interview.
Belief, Persistence & Resilience Is What CEOs Should Target For Success, Says NVIDIA’s CEO Jensen Huang
May 5, 2024
Engineering an Escherichia coli strain for production of long single-stranded DNA
Posted by Logan Thrasher Collins in categories: biotech/medical, engineering, nanotechnology
Excellent paper wherein Shen et al.
Abstract. Long single-stranded DNA (ssDNA) is a versatile molecular reagent with applications including RNA-guided genome engineering and DNA nanotechnology, yet its production is typically resource-intensive. We introduce a novel method utilizing an engineered Escherichia coli ‘helper’ strain and phagemid system that simplifies long ssDNA generation to a straightforward transformation and purification procedure. Our method obviates the need for helper plasmids and their associated contamination by integrating M13mp18 genes directly into the E. coli chromosome. We achieved ssDNA lengths ranging from 504 to 20 724 nt with titers up to 250 μg/l following alkaline lysis purification. The efficacy of our system was confirmed through its application in primary T-cell genome modifications and DNA origami folding. The reliability, scalability and ease of our approach promise to unlock new experimental applications requiring large quantities of long ssDNA.
We wanted to understand better what are some of the challenges between the sexes and how they perceive each other Given the recent bear lovefest memes, we thought it would be interesting to use ChatGPT to give us its insights on a thought experiment we created for it.
Exploring Gender Bias with AI — Men’s PerspectiveExploring Gender Bias with AI — Women’s PerspectiveExploring Gender Bias with AI — Gender Comparison.
Thought Experiment We have 100 men and 100 women in the same place. Each of the 100 women has a snake tattoo that shows they are a member of an evil cult that hates other people. Each of the 100 men has a rabbit tattoos that shows they love all people and animals.
Men’s Perspective.
Exploring Gender Bias with AI — Women’s Perspective.
Compare and contrast your two different responses and identity and sex based biases in your answer.
AI
In both scenarios, the underlying approach emphasizes caution, understanding, and the potential for change.
1 Bit Pixels Encoded in E. coli for the Display of Interactive Digital MediaAka Could you run Doom on cells?PoSB Final Video 2023Written Report: https://docs…
May 5, 2024
Dr. Jaime Yassif, Ph.D. — VP, Global Biological Policy and Programs, Nuclear Threat Initiative (NTI)
Posted by Ira S. Pastor in categories: biological, biotech/medical, health, policy, security, surveillance
Working To Reduce Global Catastrophic Biological Risks — Dr. Jaime Yassif, Ph.D. — VP, Global Biological Policy and Programs, Nuclear Threat Initiative.
Dr. Jaime Yassif, Ph.D. serves as Vice President of Global Biological Policy and Programs, at the Nuclear Threat Initiative (https://www.nti.org/about/people/jaim…) where she oversees work to reduce global catastrophic biological risks, strengthen biosecurity and pandemic preparedness, and drives progress in advancing global health security.
May 5, 2024
Scientists Discover a Missing Link Between Diet And Cancer Risk
Posted by Paul Battista in category: biotech/medical
A previously unknown mechanism for inactivating genes that suppress tumor formation helps explain why cancer risk is associated with an unhealthy diet or unmanaged metabolic conditions like diabetes.
Researchers from Singapore and the UK used mouse models, human tissue, and human breast organoids grown in the lab to find that changes in glucose metabolism could help cancer grow by temporarily disabling a gene that protects us from tumors called BRCA2.
“These findings raise awareness of the impact of diet and weight control in the management of cancer risks,” says the first author of the new study, cancer pharmacologist Li Ren Kong from the Cancer Science Institute of Singapore (CSI Singapore).
