Lifeboat Foundation

A unique genetic mutation in two siblings – that has never been seen in anyone else – has been discovered by UK researchers at the University of Exeter, pointing the way towards new treatment options for type 1 diabetes.

The mutation is in the gene for a protein called programmed death-ligand 1 (PD-L1), and a new study explains how it may be responsible for the autoimmune form of diabetes that the children developed at a very young age.

“We searched the globe, looking at all the large-scale datasets that we know of, and we haven’t been able to find another family,” says molecular geneticist Matthew Johnson, from the University of Exeter in the UK.

Revealing insights into the human condition and repairing brain disorders via novel tools for mapping and fixing brain computations.

Anthropic’s AI tool has beaten GPT-4 in key metrics and has a few surprises up its sleeve — including pontificating about its existence and realizing when it was being tested.

A doctor has explained more about the world’s first personalised mRNA cancer jab for melanoma, which is currently being tested in British patients.

Doctor Amir Khan described the vaccine as “positive news” as he discussed how it works when he appeared on Good Morning Britain on Friday (26 April).

Dr Khan said: What is happening is the melanoma is being surgically removed and then it’s being analysed for something called neoantigens.

Join our newsletter to get the latest military space news every Tuesday by veteran defense journalist Sandra Erwin.

This estimated $8 billion procurement, known as Evolved Strategic Satcom (ESS), will supplement and eventually replace the existing Advanced Extremely High Frequency (AEHF) satellite constellation. The new system will provide critical jam-resistant communication channels for the National Command Authorities and deployed forces worldwide, even in the North Polar region – a capability lacking in the current system.

Join our newsletter to get the latest military space news every Tuesday by veteran defense journalist Sandra Erwin.

Under the agreement, Agile Space — based in Durango, Colorado — will supply the main engines, attitude control thrusters, propellant tanks, and other critical propulsion components for True Anomaly’s spacecraft.

Gravitics, which develops modules for commercial space stations, will work on tactically responsive space applications for the U.S. Space Force.

Solar Cycle 25 is about to hit its peak, making this an important time to increase space weather monitoring.

WASHINGTON — Russia, as expected, vetoed April 24 a United Nations Security Council resolution crafted in response to reports that the country was developing a nuclear anti-satellite weapon.

Russia cast the only vote against the draft resolution that reaffirmed provisions in the Outer Space Treaty prohibiting the placement of nuclear weapons or other weapons of mass destruction in space. Thirteen other members of the Security Council voted in favor of the resolution while China abstained. As a permanent member of the Security Council, though, Russia’s vote acted as a veto preventing adoption of the resolution.

Japan and the United States drafted the Security Council resolution, which they billed as the first devoted to outer space issues. The resolution directed members to uphold Article 4 of the Outer Space Treaty, which forbids countries from placing nuclear weapons in orbit or on celestial bodies. It also called on countries not to develop nuclear weapons or other weapons of mass destruction specifically designed to be placed in orbit.