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The first fully complete human genome with no gaps is now available to view for scientists and the public, marking a huge moment for human genetics. Announced in a preprint in June 2021, six papers have now been published in the journal Science. They describe the painstaking work that goes into sequencing an over 6 billion base pair genome, with 200 million added in this new research. The new genome now adds 99 genes likely to code for proteins and 2,000 candidate genes that were previously unknown.

Many will be asking: “wait, didn’t we already sequence the human genome?” In part, yes – in 2000, the Human Genome Sequencing Consortium published their first drafts of the human genome, results that subsequently paved the way for almost every facet of human genetics available today.

The most recent draft of the human genome has been used as a reference since 2013. But weighed down by impractical sequencing techniques, these drafts left out the most complex regions of our DNA, which make up around 8 percent of the total genome. This is because these sequences are highly repetitive and contain many duplicated regions – attempting to put them together in the right places is like trying to complete a jigsaw puzzle where all the pieces are the same shape and have no image on the front. Long gaps and underrepresentation of large, repeating sequences made it so that this genetic material has been excluded for the past 20 years. Scientists had to come up with more accurate methods of sequencing to illuminate the darkest corners of the genome.

Adenosine, a neurotransmitter, has been found to act as a brake on dopamine, another neurotransmitter involved in motor control, by researchers at Oregon Health & Science University. The findings, which were published in the journal Nature, reveal that adenosine and dopamine operate in a push-pull dynamic in the brain.

“There are two neuronal circuits: one that helps promote action and the other that inhibits action,” said senior author Haining Zhong, Ph.D., a scientist with the OHSU Vollum Institute. “Dopamine promotes the first circuit to enable movement, and adenosine is the ‘brake’ that promotes the second circuit and brings balance to the system.”

The discovery has the potential to immediately suggest new avenues for drug development to treat the symptoms of Parkinson’s disease is a movement disorder that is believed to be caused by the loss of dopamine-producing cells in the brain.

Dynamic systems theory of neural systems.

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If one were to argue that space is made of food, one such moon of Saturn would make a great case for it, as this ravioli-shaped object orbits the ringed planet while exhibiting a ring of its own, only it’s a lot more solid than Saturn’s massive hula hoops and is often referred to as its equatorial bulge. This is Saturn’s moon, Pan, which was discovered by M.R. Showalter in 1990 after examining Voyager 2 images from 1981.

Read more about A 107-year-old Einstein theory on the origin of the universe is absolutely Right.

ATLANTA — Three years after being named the first-ever co-valedictorians at West Forsyth High School, the Kashlan triplets graduated from Georgia Tech at 18-years-old.

Adam, Zane, and Rommi Kashlan earned neuroscience degrees with minors in health and medical sciences. They completed their degrees a year early and with honors. The trio will head to Boston to work and conduct research at Harvard Medical School.

Continue reading “Triplets graduate from Georgia Tech at 18 with neuroscience degrees” »

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Researchers from the Korea Advanced Institute of Science and Technology (KAIST), Pusan National University and CNRS have developed an artificial muscle that is 17 times more powerful than that of humans. The muscle made of graphene-liquid crystal elastomer-based fiber bundles will reportedly be commercialized through a Korean company. Image The main factor that hinders the development of high-performance artificial muscles is that scientists are not able to mechanically select a certain part of the artificial muscle to contract and expand. Large and bulky artificial muscles are not accurate enough.

Researchers at The University of Texas at Austin and Texas A&M University have used electronic tattoo (e-tattoo) technology to measure stress levels, by attaching a device to people’s palms (AKA electrodermal activity or EDA sensing). The researchers created a graphene-based e-tattoo that attaches to the palm, is nearly invisible and connects to a smart watch. Image In June 2022, researchers from the same universities also developed a graphene-based electronic tattoo that can be worn on the wrist for hours and deliver continuous blood pressure measurements at an accuracy level exceeding nearly all available options on the market today.