Lifeboat Foundation

Increasingly dense cell clusters in growing tumors convert blood vessels into fiber-filled channels. This makes immune cells less effective, as findings by researchers from ETH Zurich and the University of Strasbourg suggest. Their research is published in Matrix Biology.

It was almost ten years ago that researchers first observed that tumors occurring in different cancers—including colorectal cancer, breast cancer and melanoma—exhibit channels leading from the surface to the inside of the cell cluster. But how these channels form, and what functions they perform, long remained a mystery.

Through a series of elaborate and detailed experiments, the research groups led by Viola Vogel, Professor of Applied Mechanobiology at ETH Zurich, and Gertraud Orend from the University of Strasbourg have found possible answers to these questions. There is a great deal of evidence to suggest that these channels, which the researchers have dubbed tumor tracks, were once blood vessels.

As Africa splits into two pieces, scientists predict the beginning of the rarest natural phenomena. Researchers believe that in the distant future, the creation of a new ocean may result in the division of Africa into two pieces. The separation of two significant portions of the continent may eventually lead to the formation of a new body of water. In millions of years, landlocked nations like Zambia and Uganda might have their own coasts.

The splitting of an one tectonic plate into two or more tectonic plates divided by divergent plate borders is known as rifting, according to Science Direct. Where the Earth’s tectonic plates separate, a lowland area known as the rift valley arises, according to National Geographic.

These rift valleys can be found both on land and on the ocean’s floor. According to IFLScience research, this event dates back at least 138 million years to the time when South America and Africa became separated into separate continents. According to NBC News, the Red Sea and the Gulf of Aden were formed as a result of the Arabian plate moving away from Africa for the past 30 million years.

With the aid of some sea slugs, University of Nebraska–Lincoln chemists have discovered that one of the smallest conceivable tweaks to a biomolecule can elicit one of the grandest conceivable consequences: directing the activation of neurons.

Their discovery came from investigating peptides, the short chains of amino acids that can transmit signals among cells, including neurons, while populating the central nervous systems and bloodstreams of most animals. Like many other molecules, an amino acid in a peptide can adopt one of two forms that feature the same atoms, with the same connectivity, but in mirror-image orientations: L and D.

Chemists often think of those two orientations as the left and right hands of a molecule. The L orientation is by far the more common in peptides, to the point of being considered the default. But when enzymes do flip an L to a D, the seemingly minor about-face can turn, say, a potentially therapeutic molecule into a toxic one, or vice versa.

Brainoids — tiny clumps of human brain cells — are being turned into living artificial intelligence machines, capable of carrying out tasks like solving complex equations. The team finds out how these brain organoids compare to normal computer-based AIs, and they explore the ethics of it all.

Sickle cell disease is now curable, thanks to a pioneering trial with CRISPR gene editing. The team shares the story of a woman whose life has been transformed by the treatment.

We can now hear the sound of the afterglow of the big bang, the radiation in the universe known as the cosmic microwave background. The team shares the eerie piece that has been transposed for human ears, named by researchers The Echo of Eternity.

Quantum computing systems have the potential to outperform classical computers on some tasks, helping to solve complex real-world problems in shorter times. Research teams worldwide have thus been trying to realize this quantum advantage over traditional computers, by creating and testing different quantum systems.

Researchers at Tsinghua University recently developed a new programmable quantum phononic processor with trapped ions. This processor, introduced in a paper in Nature Physics, could be easier to scale up in size than other previously proposed photonic quantum processors, which could ultimately enable better performances on complex problems.

“Originally, we were interested in the proposal of Scott Aaronson and others about Boson sampling, which might show the quantum advantages of simple linear optics and photons,” Kihwan Kim, one of the researchers who carried out the study, told Phys.org. “We were wondering if it is possible to realize it with the phonons in a trapped ion system.”

Art projects can fundamentally be anything you like, as long as you say they’re art at the end of it all. They don’t always work, or work well, but they often explore new ideas. Often, artists working on installations fall back on similar tools and techniques used by the maker community. [Julian] is no exception, and his Biotic Explorers work has many touchstones that will be familiar to the Hackaday set.

The Biotic Explorers Research Group is a broad art project, involving the creation of a fictitious scientific association. [Julian] created imaginary scientists, reports, and research to flesh out this world. The project culminates in the development of a prototype communications system, which uses pH sensors at either end of a fungal network in soil to send messages.

Liquids are applied to change the pH of the system, which can be picked up at the other end of the soil bed. The pH levels are read as digital signals, with pH levels either side of neutral reading as high and low bits. pH sensors can be expensive, so [Julian] chose the cheapest available, and tapped into their LCD display lines to read their output into an microcontroller. The system displays data using commonly available OLED displays, and hobby servo motors are used to control the dispensing of liquid.

Quantum mechanics had a disordered beginning in the 1920s, and is still developing today. Science is rarely a done deal, says Chanda Prescod-Weinstein

Columnist By Chanda Prescod-Weinstein

The ancient Celts were fierce warriors who lived in mainland Europe. But during the Renaissance, an idea took hold that they lived in the British Isles.

The relationship between the individual human subject and the world was once the central focus of Western philosophy. Modern neuroscience has instead tended to assume that the world is purely material and physical, and the problem of consciousness a question of how to generate thought from matter. Yet, we are no closer to solving the deep puzzle of consciousness and many argue that the American philosopher Thomas Nagel is right when he maintains that the question of consciousness ‘cannot be detached from subject and object’.

Is the notion that the world is purely material a fundamental mistake? Would we be more likely to unlock the mysteries of consciousness by once again adopting the framework of the subject and object? Or will slow, piecemeal advances in neuroscience and analytic philosophy eventually yield the answers that we have been searching for?

Revolutionary cognitive psychologist Donald Hoffman (joining us live from across the pond), neuroscientist Hannah Critchlow and philosopher Sam Coleman battle to unlock consciousness. Hosted by award-winning novelist Joanna Kavenna.