Lifeboat Foundation

Two key proteins linked to cell division can reliably predict disease recurrence in prostate cancer after radiotherapy treatment, according to new research.

Using an inexpensive and widely available technique in the clinic, the researchers evaluated a range of proteins in prostate tumor biopsies and determined that the phosphatase and tensin homolog (PTEN) and geminin proteins are key markers associated with cancer relapse after radiotherapy.

Based on their results, the team at The Institute of Cancer Research, London, reported that patients with tumors showing loss of PTEN were almost three times more likely to experience recurrence than those with ‘normal’ PTEN. Similarly, the data showed a 70 percent increase in the likelihood of experiencing recurrence in patients with tumors that had a 10 percent increase in geminin.

The FAA has Starship on their launch calendar! The biggest step towards colonizing Mars is perhaps a week away. But the question remains: why are humans going to make the choice to spend the rest of their lives on such a hostile planet? Well, for the main reasons that humans do anything.
Money.
#space #spacex #nasa.

Please support my channel! EARLY VIDEO RELEASES, DISCORD MEMBERSHIP AND EXCLUSIVE CONTENT PLUS 15% OFF MERCH!
https://www.patreon.com/AngryAstronaut.
https://www.paypal.com/paypalme/AngryAstro.

Continue reading “Starship launches 4/10!!! Plus, why SpaceX Mars Colonists will be the richest humans alive!” »

Lifestyle behaviors such as eating well and exercising can be significant factors in one’s overall health. But the risk of developing cancer is predominantly at the whim of an individual’s genetics.

Our bodies are constantly making copies of our genes to produce new cells. However, there are occasional mistakes in those copies, a phenomenon geneticists call mutation. In some cases, these mistakes can alter proteins, fuse genes and change how much a gene gets copied, ultimately impacting a person’s risk of developing cancer. Scientists can better understand the impact of mutations by developing predictive models for tumor activity.

Christopher Plaisier, an assistant professor of biomedical engineering in the Ira A. Fulton Schools of Engineering at Arizona State University, is developing a software tool called OncoMerge that uses genetic data to improve cancer modeling technology.

Humans are known to perceive the environment around them differently based on the situation they are in and their own feelings and sensations. Internal states, such as fear, arousal or hunger can thus affect the ways in which sensory information is processed and registered by the brain.

Researchers at Beth Israel Deaconess Medical Center, Boston Children’s Hospital, and Peking University have recently carried out a study investigating the possible effects of serotonin, a neurotransmitter known to regulate sleep, mood, sexual desire, and other inner states, in the processing of visual information. Their findings, published in Neuron, suggest that serotonergic neurons in the brainstem (i.e., the central trunk of the mammalian brain) gate the transfer of visual information from the eyes to the thalamus, an egg-shaped area of the brain.

“Internal states are known to affect sensory perception and processing, but this was generally thought to occur in the cortex or thalamus,” Chinfei Chen, one of the researchers who carried out the study, told Medical Xpress. “One of our previous studies revealed that arousal can suppress certain visual information channels at an earlier stage of the visual pathway–at the connection between the mouse retina and the thalamus, before the information even reaches the brain. This form of ‘filtering’ of information suggests a very efficient means of processing only relevant information.”

Symbiont could enable microfactories to produce biochemicals for food, farming and drugs.

Footage of unknown snailfish captured by researchers from Western Australia and Tokyo in Izu-Ogasawara trench.

A “grand unifying theory” of brain ageing suggests malfunctioning mitochondria might be to blame for Alzheimer’s and other brain conditions. And this new avenue of exploration already has some potential therapies at the ready.

A paper in Nature reports the discovery of a superconductor that operates at room temperatures and near-room pressures. The claim has divided the research community.

An open letter signed by more than 1,100 technology and business industry leaders calls for a six-month moratorium on the race to develop artificial intelligence (AI), and in particular large language models like ChatGPT-4.

ChatGPT-4 is an example of AI exhibiting human-competitive intelligence and poses a risk to humanity without managed care.