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Jul 29, 2023

Express Delivery of Proton Therapy

Posted by in category: biotech/medical

A new scheme could increase the efficiency of a high-dose cancer radiation therapy and mitigate patient discomfort by reducing particle loss in proton beams.

Jul 29, 2023

A Pair of New Tetraquarks

Posted by in category: particle physics

CERN’s Large Hadron Collider has detected the signals of two new four-quark states that are unusual because of their charges and their quark compositions.

Jul 29, 2023

The Fermi Paradox Has An Incredibly Simple Solution

Posted by in categories: alien life, existential risks

It’s possibly the most famous question in all of science — where is everyone? Join us today for deep dive into Fermi Paradox. 🌏 Get exclusive NordVPN deal here ➵ https://NordVPN.com/coolworlds It’s risk free with Nord’s 30 day money-back guarantee!✌

The Fermi Paradox has been a topic of keen debate amongst scientists, astronomers and the rest of us for more than seven decades. We can’t resist the urge to speculate about aliens! But what is the paradox even really about? What explanations have been offered? Today, we explore this famous question, and offer a mind-shifting explanation.

Continue reading “The Fermi Paradox Has An Incredibly Simple Solution” »

Jul 29, 2023

Has JWST shown the Universe is TWICE as old as we think?!

Posted by in categories: cosmology, robotics/AI

Go to https://brilliant.org/drbecky to get a 30-day free trial and the first 200 people will get 20% off their annual subscription. A new research study has come out claiming that to explain the massive galaxies found at huge distances in James Webb Space Telescope images, the Universe is older than we think, at 26.7 billion years (rather than 13.8 billion years old). In this video I’m diving into that study, looking at what model they used to get at that claim (a combination of the expansion of the universe and “tired light” ideas of redshift), how this impacts our best model of the Universe and the so-called “Crisis is Cosmology”, and why I’m not convinced yet!

#astronomy #JWST #cosmology.

Continue reading “Has JWST shown the Universe is TWICE as old as we think?!” »

Jul 29, 2023

Dr. Robert Sapolsky: Science of Stress, Testosterone & Free Will | Huberman Lab Podcast #35

Posted by in categories: biotech/medical, life extension, neuroscience, science

In this episode, I interview Dr. Robert Sapolsky, Ph.D., Professor of Biology, Neurology & Neurosurgery at Stanford University. We discuss stress, what defines short-term versus long-term stress, and how stress can be beneficial or detrimental, depending on the context. We also discuss stress mitigation and how our sense of control over stress mitigation techniques, including exercise, determine health outcomes. Dr. Sapolsky explains some of the key effects of the hormone testosterone — how it can amplify pre-existing tendencies for aggression or sexual behavior, but that it does not produce those behaviors per se. He also explains how testosterone impacts our social hierarchies, sense of confidence, and willingness to embrace challenges of different kinds. He also explains how our behaviors and perceptions shape testosterone levels. And we discuss estrogen and the powerful role it plays in brain development, health and longevity. Finally, we discuss free will, what it means to have free will, and if we have any free will, including how knowledge alone might allow us to make better decisions for ourselves and society.

#HubermanLab #Testosterone #Stress.

Continue reading “Dr. Robert Sapolsky: Science of Stress, Testosterone & Free Will | Huberman Lab Podcast #35” »

Jul 29, 2023

Episode 9: Solo — Why Is There Something Rather than Nothing?

Posted by in categories: open access, physics, space

New Patreon page! https://www.patreon.com/seanmcarroll.

Blog post: https://www.preposterousuniverse.com/podcast/2018/08/13/epis…n-nothing/

Continue reading “Episode 9: Solo — Why Is There Something Rather than Nothing?” »

Jul 29, 2023

God is not a Good Theory (Sean Carroll)

Posted by in category: cosmology

Lecture from the 2nd mini-series (Is “God” Explanatory) from the “Philosophy of Cosmology” project. A University of Oxford and Cambridge Collaboration.

Jul 29, 2023

Bioengineered Probiotics: Synthetic Biology Can Provide Live Cell Therapeutics for the Treatment of Foodborne Diseases

Posted by in categories: bioengineering, biotech/medical, economics, food, health

The rising prevalence of antibiotic resistant microbial pathogens presents an ominous health and economic challenge to modern society. The discovery and large-scale development of antibiotic drugs in previous decades was transformational, providing cheap, effective treatment for what would previously have been a lethal infection. As microbial strains resistant to many or even all antibiotic drug treatments have evolved, there is an urgent need for new drugs or antimicrobial treatments to control these pathogens. The ability to sequence and mine the genomes of an increasing number of microbial strains from previously unexplored environments has the potential to identify new natural product antibiotic biosynthesis pathways. This coupled with the power of synthetic biology to generate new production chassis, biosensors and “weaponized” live cell therapeutics may provide new means to combat the rapidly evolving threat of drug resistant microbial pathogens. This review focuses on the application of synthetic biology to construct probiotic strains that have been endowed with functionalities allowing them to identify, compete with and in some cases kill microbial pathogens as well as stimulate host immunity. Weaponized probiotics may have the greatest potential for use against pathogens that infect the gastrointestinal tract: Vibrio cholerae, Staphylococcus aureus, Clostridium perfringens and Clostridioides difficile. The potential benefits of engineered probiotics are highlighted along with the challenges that must still be met before these intriguing and exciting new therapeutic tools can be widely deployed.

The discovery and application of antibiotic drugs is among the most significant accomplishments of medical science. Alexander Fleming’s discovery of penicillin (Fleming, 1929) and subsequent discovery and development of multiple classes of natural product antibiotics have been transformational to modern society. These compounds have yielded cheap and effective treatments for diseases caused by common bacterial infections that would previously have proven fatal. The advent of effective antibiotic drugs has made it possible to survive complex surgical procedures like open heart surgery and organ transplants and extended the average human life-span (Riley, 2005; Kaviani et al., 2020). The benefits of readily available antibiotic drugs have extended into agriculture and aquaculture, making it possible to increase productivity of farmed animals (Park et al., 1994; Patel et al., 2020).

Jul 29, 2023

New quantum magnet unleashes electronics potential

Posted by in categories: quantum physics, robotics/AI

Researchers discovered how to control the anomalous Hall effect and Berry curvature to create flexible quantum magnets for use in computers, robotics, and sensors.

Jul 29, 2023

New protein-based nano-switches could lead to faster, more accurate diagnostic tests

Posted by in categories: bioengineering, biotech/medical, nanotechnology

QUT researchers have developed a new approach for designing molecular ON-OFF switches based on proteins which can be used in a multitude of biotechnological, biomedical and bioengineering applications.

The research team demonstrated that this novel approach allows them to design and build faster and more accurate diagnostic tests for detecting diseases, monitoring water quality and detecting environmental pollutants.

Professor Kirill Alexandrov, of the QUT School of Biology and Environmental Science, lead scientist on the CSIRO-QUT Synthetic Biology Alliance and a researcher with the ARC Centre of Excellence in Synthetic Biology, said that the new technique published in the prestigious scientific journal Nature Nanotechnology demonstrated that protein switches could be engineered in a predictable way.