Two RNA-editing therapies for genetic diseases have recently gained approval for clinical trials, raising hopes for safer treatments.
The challenge is huge: There’s a lot we don’t understand about Alzheimer’s disease, but we do know that patient’s brains tend to accumulate toxic tau and amyloid-beta proteins, so most research has focused on those targets.
That approach has led to new drugs that can slow the progression of Alzheimer’s to a small degree, but we’ve yet to find anything that can reverse the damage the disease does to the brain.
The big idea: Synapses — the connections between brain neurons — need a protein called “KIBRA” in order to form memories, and there’s a link between certain variants of the KIBRA gene and developing Alzheimer’s.
OpenAI on Thursday announced Sora, a brand new model that generates high-definition videos up to one minute in length from text prompts. Sora, which means “sky” in Japanese, won’t be available to the general public any time soon. Instead, OpenAI is making it available to a small group of academics and researchers who will assess harm and its potential for misuse.
“Sora is able to generate complex scenes with multiple characters, specific types of motion, and accurate details of the subject and background,” the company said on its website. “The model understands not only what the user has asked for in the prompt, but also how those things exist in the physical world.”
One of the videos generated by Sora that OpenAI shared on its website shows a couple walking through a snowy Tokyo city as cherry blossom petals and snowflakes blow around them.
Lucid has cut prices on the Air electric vehicle lineup by as much as $8,000 in an attempt to surge demand.
The Lucid Air Pure Rear-Wheel-Drive is now priced at $69,900. The most affordable and accessible trim of the Air features a sleek interior and exterior design and a driving range of up to 410 miles. It was previously priced at $77,400.
The Lucid Air Touring is now priced at $77,900 and features an All-Wheel-Drive powertrain that produces 620 horsepower. It was previously $85,900.
Nanotechnology is intimately intertwined with efforts to bring bottom-up synthetic cell research to the forefront, and only strengthening these bonds will expand the scope of what this might achieve.
This Review explores the development of ingestible electronics and provides a step-by-step guide for the design of ingestible electronic capsules at the system level.
Sabine Hossenfelder and Bernardo Kastrup have a theolocution on superdeterminism and free variables.
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Continue reading “The Mind-Blowing Theory That Challenges Everything We Know” »
NB Whilst claims of logical possibility intended to support reality claims (such as Swinburne’s proposal of disembodied existence) become subject to constraints of reality, those not intended to support any reality claim need not be subject to such constraints.
Selected Resources (see also part 1):
It’s not easy to calculate the watts and joules that go into a single Balenciaga pope.
How many watts and joules does it actually take to generate a single Balenciaga pope?
