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The Aubrey de Grey and Matthew O’Connor SENS AMA on reddit Monday 12th 11am PST.

I am Dr. Aubrey De Grey, biologist, gerontologist PhD and author of the book Ending Aging and Chief Science Officer at the SENS Research Foundation. I am here with researcher Dr. Matthew O’Connor from the MitoSENS project who is an expert on “allotopic expression” of mitochondrial genes. His team has been working on engineering mitochondrial genes to be expressed from the nucleus and targeted to the mitochondia as part of the MitoSENS approach to one of the damages of aging.

Each cell in the body is dependent on the efficient generation of cellular energy by mitochondria to stay alive. Critical to this process are genes encoded within the mitochondrial genome. Over time however, mutations in these genes occur as a result of constant exposure to reactive oxygen species produced by oxidative phosphorylation, the mitochondrial energy generation process. Unlike genes within the nucleus, mitochondria lack an efficient system to repair damaged DNA. This leads to accumulated mutations, resulting in mitochondrial defects and an increase in oxidative stress throughout the body. Closely correlated with this is the observation that organisms which age more slowly also consistently display lower rates of mitochondrial free radical damage. Thus, reversing and/or preventing damage to mitochondrial DNA may be a key factor in slowing the aging process.

Continue reading “Aubrey de Grey & Matthew O’Connor AMA! • /r/Futurology” »

(Phys.org)—Are time crystals just a mathematical curiosity, or could they actually physically exist? Physicists have been debating this question since 2012, when Nobel laureate Frank Wilczek first proposed the idea of time crystals. He argued that these hypothetical objects can exhibit periodic motion, such as moving in a circular orbit, in their state of lowest energy, or their “ground state.” Theoretically, objects in their ground states don’t have enough energy to move at all.

In the years since, other physicists have proposed various arguments for why the physical existence of time crystals is impossible—and most physicists do seem to think that time crystals are physically impossible because of their odd properties. Even though time crystals couldn’t be used to generate useful energy (since disturbing them makes them stop moving), and don’t violate the second law of thermodynamics, they do violate a fundamental symmetry of the laws of physics.

However, now in a new paper published in Physical Review Letters, physicists from the University of California, Santa Barbara (UCSB) and Microsoft Station Q (a Microsoft research lab located on the UCSB campus) have demonstrated that it may be possible for time crystals to physically exist.

Elon Musk blew our minds when he suggested that it’s highly likely we’re all living in a computer simulation. Seriously? Why would he think this, and how could we tell if it’s true?

Apple’s iOS might be first to support an augmented reality contact lens system currently in development at EP Global Communications, as the two companies are scheduled to meet next week to discuss potential platform integrations.

The PLANETS telescope will be our first step to seeking out biosignatures in exoplanetary atmospheres.

Watch live coverage of our OSIRIS-REx spacecraft lift off at 7:05 p.m. EDT aboard an Atlas V rocket on a mission to explore asteroid Bennu and return a sample to Earth.

Humans have failed to understand, we can’t make a new wilderness in a factory once the natural world is gone.

At the current rate, our future generations will only be able to experience what the wilderness was in historical documents.

Nice breakthrough.

Solution-processing methods are used to synthesize metal-oxide nanoparticle suspensions and thus realize efficient and stable devices.

Continue reading “Room-temperature deposition of interfacial contact layers for organic photovoltaics” »