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Dec 5, 2022

Investing in the Age of Longevity 2022 — Patrick Burgermeister — KIZOO Technology Ventures

Posted by in categories: biotech/medical, business, life extension

Patrick Burgermeister of KIZOO Technology Ventures presents at Investing in the Age of Longevity 2022. In his talk, Patrick gives an overview of KIZOO Technology Ventures’ investment strategy, with a particular focus on misson-driven investments in early stage companies that open new categories of treatment. Patrick showcases six biotech startups that form part of the company’s key investments: Cellvie, Revel, Cyclarity, LIfT BioSciences, Elastrin, and Mogling Bio.

Download the presentation slides:

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Dec 5, 2022

Federated machine learning enables the largest brain tumor study to-date, without sharing patient data

Posted by in categories: biotech/medical, health, robotics/AI

Researchers at Penn Medicine and Intel Corporation led the largest-to-date global machine learning effort to securely aggregate knowledge from brain scans of 6,314 glioblastoma (GBM) patients at 71 sites around the globe and develop a model that can enhance identification and prediction of boundaries in three tumor sub-compartments, without compromising patient privacy. Their findings were published today in Nature Communications.

“This is the single largest and most diverse dataset of glioblastoma patients ever considered in the literature, and was made possible through federated learning,” said senior author Spyridon Bakas, Ph.D., an assistant professor of Pathology & Laboratory Medicine, and Radiology, at the Perelman School of Medicine at the University of Pennsylvania. “The more data we can feed into machine learning models, the more accurate they become, which in turn can improve our ability to understand, treat, and remove glioblastoma in patients with more precision.”

Researchers studying rare conditions, like GBM, an aggressive type of brain tumor, often have patient populations limited to their own institution or geographical location. Due to privacy protection legislation, such as the Health Insurance Portability and Accountability Act of 1996 (HIPAA) in the United States, and General Data Protection Regulation (GDPR) in Europe, data sharing collaborations across institutions without compromising data is a major obstacle for many healthcare providers.

Dec 5, 2022

Nano-magnets can be used to restore damaged nerve cells —Bar-Ilan

Posted by in categories: bioengineering, nanotechnology, robotics/AI

These fundamental units of the brain and nervous system – composed of the cell body, the dendrites and the axon (a long, thin extension responsible for communicating with other cells) – receive sensory input from the external world, send motor commands to our muscles and for transform and relay the electrical signals at every step in between.

“Our novel method of creating ‘mini-brains’ opens the door to finding solutions for various neurological impairments”

Prof. Orit Shefi and doctoral student Reut Plen from the Kofkin Faculty of Engineering at Bar-Ilan University (BIU) have developed a novel technique to overcome this challenge using nanotechnology and magnetic manipulations – one of the most innovative approaches to creating neural networks. Their research was recently published in the peer-reviewed journal Advanced Functional Materials under the title “Bioengineering 3D Neural Networks Using Magnetic Manipulations.”

Dec 5, 2022

How the universe’s expansion may have stopped dark matter taking over

Posted by in category: cosmology

There’s a lot we still don’t know about dark matter – that mysterious, invisible mass that could make up as much as 85 percent of everything around us – but a new paper outlines a rather unusual hypothesis about the very creation of the stuff.

Dec 5, 2022

Masks Aren’t to Blame for the Surge in RSV and Flu Right Now

Posted by in category: biotech/medical

Here’s why the flu and RSV are surging right now—and how COVID itself may have affected our immune systems.

Dec 5, 2022

Carbon ultrafine particles accelerate lung cancer progression

Posted by in categories: biotech/medical, nanotechnology

While it may seem common knowledge that smoking is bad for your lungs, if and how ultrafine particles present in cigarette smoke impact the development and progression of lung cancer remains unclear. Working with animal models, researchers at Baylor College of Medicine sought to find how airborne ultrafine particles in smoke can change a host’s defense against lung cancer.

In a study published in the current edition of Science Advances, Dr. Cheng-Yen Chang, a postdoctoral fellow in Dr. Farrah Kheradmand’s lab in the Department of Medicine – Pulmonary at Baylor, and their team discovered that exposure to ultrafine particles alters the function of immune cells in the lungs, disabling their natural defense mechanism against tumors. They found that ultrafine particles change the cell’s primary energy source, creating new byproducts in the lungs. Accumulation of the new byproducts can decrease the host’s immune defense, allowing tumors to escape detection.

These particles are not just found in cigarette smoke; environmental and other natural fires also incompletely combust organic matter that generates ultrafine particles. Kheradmand and colleagues at Rice University had previously found that immune cells in the lungs of heavy smokers contain particles that they identified as nano-sized elemental carbon black.

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Dec 5, 2022

Former PlayStation Hacker in a Race Against Time to Fix Twitter

Posted by in category: Elon Musk

A one-time hacker has made a bold deal with Elon Musk.

Dec 4, 2022

Feeling Fatigued, Anxious or Depressed? It Might Be Your Thyroid

Posted by in category: biotech/medical

This article originally appeared on VICE Italy.

“After seeing my results, the doctor was surprised I hadn’t arrived on my hands and knees,” said Alice, who’s spent the past five years in treatment for hypothyroidism. The thyroid gland is a key organ regulating all kinds of functions in the body – meaning a defective thyroid can have a huge impact on your quality of life.

About 6 million people have thyroid disorders here in Italy and it’s estimated about 3.8 percent of the population of Europe is affected by some kind of thyroid dysfunction. But they often go unnoticed.

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Dec 4, 2022

The Theory That Could Rewrite the Laws of Physics

Posted by in category: physics

Chiara Marletto is trying to build a master theory — a set of ideas so fundamental that all other theories would spring from it. Her first step: Invoke the impossible. Read more about Marletto and David Deutsch’s constructor theory at Quanta Magazine:…-20210429/

Dec 4, 2022

The Terrifying Future of Artificial Intelligence

Posted by in categories: futurism, robotics/AI

For decades, the growth of artificial intelligence has fascinated scholars and scientists alike. Today, intelligent machines aid and streamline our lives, but the next fifty or a hundred years may yield even more powerful AI, which could elevate or transform our species. If humans do create sophisticated, super-intelligent machines, how will the growth of artificial intelligence affect the future of humanity?


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