Lifeboat Foundation

Why not eradicate disease for everyone?

Zolgensma – which treats spinal muscular atrophy, a rare genetic disease that damages nerve cells, leading to muscle decay – is currently the most expensive drug in the world. A one-time treatment of the life-saving drug for a young child costs US$2.1 million.

While Zolgensma’s exorbitant price is an outlier today, by the end of the decade there’ll be dozens of cell and gene therapies, costing hundreds of thousands to millions of dollars for a single dose. The Food and Drug Administration predicts that by2025it will be approving 10 to 20 cell and gene therapies every year.

Continue reading “New gene therapies may soon treat dozens of rare diseases, but million-dollar price tags will put them out of reach for many” »

Whether you sell or buy on Amazon — or both — this is good news.

“University Of The 3rd Age” — Seniors Staying Intellectually Challenged, Socially Engaged, And Physically And Mentally Healthy — Maya Abi Chahine, University for Seniors, American University of Beirut (AUB)

AUB (https://www.aub.edu.lb/seniors/Pages/default.aspx).

Continue reading “Maya Abi Chahine, Program Manager, University for Seniors, American University of Beirut” »

Intelligent systems engineer, STEM advocate, hip-hop artist — ashley llorens, VP, distinguished scientist, managing director microsoft research, microsoft.

Ashley Llorens (https://www.microsoft.com/en-us/research/people/allorens/) is Vice President, Distinguished Scientist & Managing Director, at Microsoft Research Outreach, where he leads a global team to amplify the impact of research at Microsoft and to advance the cause of science and technology research around the world. His team is responsible for driving strategy and execution for Microsoft Research engagement with the rest of Microsoft and with the broader science and technology community, and they invest in high-impact collaborative research projects on behalf of the company, create pipelines for diverse, world-class talent, and generate awareness of the current and envisioned future impact of science and technology research.

Continue reading “Ashley Llorens — VP, Distinguished Scientist & Managing Director, Microsoft Research Outreach” »

In other words, the mix of positives and negatives puts this potent new suite of technologies on a knife-edge. Do we have confidence that a handful of companies that have already lost public trust can take AI in the right direction? We should have ample reason for worry considering the business models driving their motivations. To advertising-driven companies like Google and Facebook, it’s clearly beneficial to elevate content that travels faster and draws more attention—and misinformation usually does —while micro-targeting that content by harvesting user data. Consumer product companies, such as Apple, will be motivated to prioritize AI applications that help differentiate and sell their most profitable products—hardly a way to maximize the beneficial impact of AI.

Yet another challenge is the prioritization of innovation resources. The shift online during the pandemic has led to outsized profits for these companies, and concentrated even more power in their hands. They can be expected to try to maintain that momentum by prioritizing those AI investments that are most aligned with their narrow commercial objectives while ignoring the myriad other possibilities. In addition, Big Tech operates in markets with economies of scale, so there is a tendency towards big bets that can waste tremendous resources. Who remembers IBM’s Watson initiative? It aspired to become the universal, go-to digital decision tool, especially in healthcare—and failed to live up to the hype, as did the trendy driverless car initiatives of Amazon and Google parent Alphabet. While failures, false starts, and pivots are a natural part of innovation, expensive big failures driven by a few enormously wealthy companies divert resources away from more diversified investments across a range of socially productive applications.

Continue reading “Big Tech’s Stranglehold on Artificial Intelligence Must Be Regulated” »

Improving Quality Of Life & Health, For Hundreds Of Millions Globally, Suffering Food Allergies & Intolerances — Lisa Gable, Chief Executive Officer, Food Allergy Research & Education (FARE)

Lisa Gable is the Chief Executive Officer, of Food Allergy Research & Education (FARE — https://www.foodallergy.org), an organization with a mission to improve the quality of life and the health of 85 million Americans with food allergies and food intolerances, including 32 million of those are at risk for life-threatening anaphylaxis, and to provide them hope through the promise of new treatments. To date FARE has turned over $100 million in donor gifts into ground-breaking research and has provided a voice for the community, advocating on its behalf and offering hope for a better tomorrow.

Continue reading “Lisa Gable — Chief Executive Officer — Food Allergy Research & Education (FARE)” »

We hand out cash freely to some people, while we plague others with fraudulent debt notices that may cripple financially, with dire ultimate consequences.

There is a case to be made for a universal basic income (UBI) — an unconditional payment to everyone that ensures the basics of life are catered for. It may give people security to leave a bad situation, or freedom to pursue a new future. No conditions means no bureaucracy, which improves productivity and efficiency, and the universal nature of UBI means even conservatives can get on board.

But how to afford such a payment? Surely giving away free money would blow the budget?

Continue reading “With jobkeeper back on the table, it’s once again a good time to talk about how we should deal with welfare as a country” »

Something to consider.

“The whole idea of lifestyle choices as something everyone can tap into is misleading, when in fact that choice is constrained by what is available to people,” he said. “This is where policy solutions or investments into these neighborhoods to make up for historical disinvestment becomes so important.”

Summary: The neighborhood you live in could have an impact on your brain and cardiovascular health, a new study reports.

Continue reading “Where You Live Can Greatly Affect Your Heart and Brain Health” »

Olympic stadiums can be costly and wasteful. Some have argued for a single, more sustainable, location that can be used year after year.

The summer Olympics have been a quadrennial tradition ever since the late 1800s—when modern sports and rivalries freshened up the ancient tradition. Since COVID-19 crashed the schedule for last years’ events, now the world is gearing up again for another round of competition in Tokyo.

Transporting athletes and fans from all over the world and to cities hosting the Olympic games comes with a gigantic carbon footprint, for example, the 2021 London Olympics had an estimated footprint of over 400 thousand tons of CO₂ emissions. Constantly building brand-new stadiums every few years that often go unused after the games, with very few exceptions, is also extremely wasteful. The 2016 Rio Olympics whipped up a whopping 3.6 million tonnes of carbon when including all that went into infrastructure. Eerie listicles of decaying stadiums, including Rio’s, litter the internet with costly examples of the wasted hundreds of millions of dollars worth of labor and materials that go into just one site.

Continue reading “The argument for a permanent Olympic City” »