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They Are Waiting for Us To Die: Aestivation Hypothesis

What if advanced civilizations aren’t absent—they’re just waiting? What if they looked at our universe, full of burning stars and abundant energy, and decided it’s too hot, too expensive, too wasteful to be awake? What if everyone else has gone into hibernation, sleeping through the entire age of stars, waiting trillions of years for the universe to cool? The Aestivation Hypothesis offers a stunning solution to the Fermi Paradox: intelligent civilizations aren’t missing—they’re deliberately dormant, conserving energy for a colder, more efficient future. We might be the only ones awake in a sleeping cosmos.

Over the next 80 minutes, we’ll explore one of the most patient answers to why we haven’t found aliens. From thermodynamic efficiency to cosmic hibernation, from automated watchers keeping vigil to the choice between experiencing now versus waiting for optimal conditions trillions of years ahead, we’ll examine why the rational strategy might be to sleep through our entire era. This changes everything about the Fermi Paradox, the Drake Equation, and what it means to be awake during the universe’s most “expensive” age.

CHAPTERS:

0:00 — Introduction: The Patience of Stars.

4:30 — The Fermi Paradox Once More.

8:20 — Introducing the Aestivation Hypothesis.

Framework sets new benchmarks for 3D atom maps in amorphous materials

Researchers at the California NanoSystems Institute at UCLA published a step-by-step framework for determining the three-dimensional positions and elemental identities of atoms in amorphous materials. These solids, such as glass, lack the repeating atomic patterns seen in a crystal. The team analyzed realistically simulated electron-microscope data and tested how each step affected accuracy.

The team used algorithms to analyze rigorously simulated imaging data of nanoparticles—so small they’re measured in billionths of a meter. For amorphous silica, the primary component of glass, they demonstrated 100% accuracy in mapping the three-dimensional positions of the constituent silicon and oxygen atoms, with precision about seven trillionths of a meter under favorable imaging conditions.

While 3D atomic structure determination has a history of more than a century, its application has been limited to crystal structures. Such techniques depend on averaging a pattern that is repeated trillions of times.

Deep-learning algorithms enhance mutation detection in cancer and RNA sequencing

Researchers from the Faculty of Engineering at The University of Hong Kong (HKU) have developed two innovative deep-learning algorithms, ClairS-TO and Clair3-RNA, that significantly advance genetic mutation detection in cancer diagnostics and RNA-based genomic studies.

The pioneering research team, led by Professor Ruibang Luo from the School of Computing and Data Science, Faculty of Engineering, has unveiled two groundbreaking deep-learning algorithms—ClairS-TO and Clair3-RNA—set to revolutionize genetic analysis in both clinical and research settings.

Leveraging long-read sequencing technologies, these tools significantly improve the accuracy of detecting genetic mutations in complex samples, opening new horizons for precision medicine and genomic discovery. Both research articles have been published in Nature Communications.

Facebook Admits the Social Network Isn’t Social

Facebook admitted something that should have been front-page news.

In an FTC antitrust filing, Meta revealed that only 7% of time on Instagram and 17% on Facebook is spent actually socializing with friends and family.

The rest?

Algorithmically selected content. Short-form video. Engagement optimized by AI.

This wasn’t a philosophical confession. It was a legal one. But it quietly confirms what many of us have felt for years:

What we still call “social networks” are not social.

They are attention machines.

AI Now Has a Primitive Form of Metacognition

In this video I break down recent research exploring metacognition in large language model ensembles and the growing shift toward System 1 / System 2 style AI architectures.
Some researchers are no longer focusing on making single models bigger. Instead, they are building systems where multiple models interact, critique each other, and dynamically switch between fast heuristic reasoning and slower deliberate reasoning. In other words: AI systems that monitor and regulate their own thinking.

Artificial metacognition: Giving an AI the ability to ‘think’ about its ‘thinking’
https://theconversation.com/artificia… System 1 to System 2: A Survey of Reasoning Large Language Models https://arxiv.org/abs/2502.17419 The Illusion of Thinking: Understanding the Strengths and Limitations of Reasoning Models via the Lens of Problem Complexity https://dl.acm.org/doi/10.1145/374625… Emotions? Towards Quantifying Metacognition and Generalizing the Teacher-Student Model Using Ensembles of LLMs https://arxiv.org/abs/2502.17419 Metacognition https://research.sethi.org/metacognit… Robot passes the mirror test by inner speech https://www.sciencedirect.com/science… METIS: Metacognitive Evaluation for Intelligent Systems https://research.sethi.org/metacognit… Distinguishing the reflective, algorithmic, and autonomous minds: Is it time for a tri-process theory? Get access Arrow https://academic.oup.com/book/6923/ch… #science #explained #news #research #sciencenews #ai #robots #artificialintelligence.

From System 1 to System 2: A Survey of Reasoning Large Language Models.
https://arxiv.org/abs/2502.

The Illusion of Thinking: Understanding the Strengths and Limitations of Reasoning Models via the Lens of Problem Complexity.
https://dl.acm.org/doi/10.1145/374625

Emotions? Towards Quantifying Metacognition and Generalizing the Teacher-Student Model Using Ensembles of LLMs.
https://arxiv.org/abs/2502.

Mapping cell development with mathematics-informed machine learning

The development of humans and other animals unfolds gradually over time, with cells taking on specific roles and functions via a process called cell fate determination. The fate of individual cells, or in other words, what type of cells they will become, is influenced both by predictable biological signals and random physiological fluctuations.

Over the past decades, medical researchers and neuroscientists have been able to study these processes in greater depth, using a technique known as single-cell RNA sequencing (scRNA-seq). This is an experimental tool that can be used to measure the gene activity of individual cells.

To better understand how cells develop over time, researchers also rely on mathematical models. One of these models, dubbed the drift-diffusion equation, describes the evolution of systems as the combination of predictable changes (i.e., drift) and randomness (i.e., diffusion).

Washington state proposes new 3D-printed gun controls with ‘blocking features’ and blueprint detection algorithm — proposal would carry sentences of five years in prison, $15,000 fine for violation

All three are explained in more detail in the bill, but arrive at broadly the same destination. This law, if approved, would prevent 3D printer brands from selling their wares in Washington State without stringent controls to prevent the printing of 3D firearms, or indeed parts that could be used to modify existing weapons.

According to the bill, violating this proposed law would be a class C felony, which means anyone found in violation of these terms could face up to five years in prison and a $15,000 fine.

Washington is not the first state to propose addressing 3D-printed firearms by way of legislation, and is unlikely to be the last. Earlier this month New York took steps to ban 3D-printed guns, proposing the mandating of 3D printer safeguards and cracking down on the sharing and possession of 3D files containing guns or gun components.

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