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Category: engineering

Multimode quantum entanglement achieved via dissipation engineering

A research team led by Prof. Lin Yiheng from the University of Science and Technology of China (USTC), collaborating with Prof. Yuan Haidong from the Chinese University of Hong Kong, succeeded in generating multipartite quantum entangled states across two, three, and five modes using controlled dissipation as a resource. Their study is published in Science Advances.

Multimode entanglement is a key resource in quantum computation, communication, simulation, and sensing. One of the major challenges in achieving stable and scalable multimode entanglement lies in the inherent susceptibility of quantum systems to environmental noise—a phenomenon known as . To mitigate dissipative effects, conventional preparation methods often require isolating the system from its surroundings.

Recent theoretical and experimental works have revealed an innovative perspective: when properly engineered, dissipation can be transformed into a resource for generating specific quantum states—known as dissipation engineering. However, previous related experiments were confined to single-mode and two-mode quantum systems, and significant challenges remain in the experimental realization of entangled states across multimode bosonic systems.

Molecular motors drive new non-invasive cancer therapies

Imagine tiny machines, smaller than a virus, spinning inside cancer cells and rewiring their behavior from within. No surgery, no harsh chemicals, just precision at the molecular level.

Two researchers from the Artie McFerrin Department of Chemical Engineering at Texas A&M University are investigating light-activated molecular motors—nanometer-sized machines that can apply from within cells to target and selectively disrupt cancerous activity.

Chemical engineering professor Dr. Jorge Seminario and postdoctoral associate Dr. Diego Galvez-Aranda have contributed to pioneering research by demonstrating a new frontier in non-invasive cancer therapies. The recently published manuscript in the Journal of the American Chemical Society continues this line of investigation.

Scientists create a paper-thin light that glows like the sun

Scientists have developed an ultra-thin, paper-like LED that emits a warm, sunlike glow, promising to revolutionize how we light up our homes, devices, and workplaces. By engineering a balance of red, yellow-green, and blue quantum dots, the researchers achieved light quality remarkably close to natural sunlight, improving color accuracy and reducing eye strain.

Engineered stem cells yield millions of tumor-fighting natural killer cells at reduced cost

Chinese researchers have developed a novel method to efficiently engineer natural killer (NK) cells for cancer immunotherapy. NK cells are central to early antiviral and anticancer defense—among other immune system roles—making them well-suited for cancer immunotherapy. For example, chimeric antigen receptor (CAR)-NK therapy involves adding a lab-built receptor (a CAR) to an NK cell, enabling it to recognize a specific antigen on a cancer cell and attack it.

However, conventional CAR-NK immunotherapies rely primarily on mature NK cells isolated from , such as peripheral blood or cord blood, which poses multiple challenges, including high heterogeneity, low engineering efficiency, high handling costs, and time-intensive processing.

Now a research team led by Prof. Wang Jinyong from the Institute of Zoology of the Chinese Academy of Sciences has developed a novel method to generate induced (that is, lab-generated) NK (iNK) cells and CAR-engineered iNK (CAR-iNK) cells from CD34+ and (HSPCs) derived from cord blood.

Strain engineering enhances spin readout in quantum technologies, study shows

Quantum defects are tiny imperfections in solid crystal lattices that can trap individual electrons and their “spin” (i.e., the internal angular momentum of particles). These defects are central to the functioning of various quantum technologies, including quantum sensors, computers and communication systems.

Reliably predicting and controlling the behavior of quantum defects is thus very important, as it could pave the way for the development of better performing quantum systems tailored for specific applications. A property closely linked to the dependability of quantum technologies is the so-called spin readout contrast, which essentially determines how clear it is to distinguish between two different spin states in a system.

Researchers at the Harbin Institute of Technology (Shenzhen), the HUN-REN Wigner Research Center for Physics, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences and other institutes recently showed that strain engineering (i.e., stretching or compressing materials) could be used to control how quantum defects behave and enhance spin readout contrast in quantum systems.

Nanoparticle vaccine prevents multiple cancers and stops metastasis in mice

A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic and triple-negative breast cancer in mice. Not only did up to 88% of the vaccinated mice remain tumor-free (depending on the cancer), but the vaccine reduced—and in some cases completely prevented—the cancer’s spread.

The study is published in Cell Reports Medicine.

“By engineering these nanoparticles to activate the immune system via multi-pathway activation that combines with cancer-specific antigens, we can prevent with remarkable survival rates,” says Prabhani Atukorale, assistant professor of biomedical engineering in the Riccio College of Engineering at UMass Amherst and corresponding author on the paper.

MIT and Harvard Build “Invisible” Immune Cells That Obliterate Cancer

MIT and Harvard scientists have created engineered CAR-NK cells that can hide from the immune system and more effectively destroy cancer.

The cells are designed to suppress immune-rejection signals and enhance tumor-killing power. Tested in humanized mice, they wiped out cancer while avoiding dangerous immune reactions.

A major breakthrough in immune engineering.

Engineered CAR-NK cells could evade immune rejection and target cancer more effectively

One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar to CAR-T cells, these cells can be programmed to attack cancer cells.

MIT and Harvard Medical School researchers have now come up with a new way to engineer CAR-NK cells that makes them much less likely to be rejected by the patient’s , which is a common drawback of this type of treatment.

The new advance may also make it easier to develop “off-the-shelf” CAR-NK cells that could be given to patients as soon as they are diagnosed. Traditional approaches to engineering CAR-NK or CAR-T cells usually take several weeks.

Flash Joule heating lights up lithium extraction from ores

A new one‑step, water‑, acid‑, and alkali‑free method for extracting high‑purity lithium from spodumene ore has the potential to transform critical metal processing and enhance renewable energy supply chains. The study is published in Science Advances.

As the demand for lithium continues to rise, particularly for use in , smartphones and power storage, current extraction methods are struggling to keep pace. Extracting lithium from is a lengthy process, and traditional methods that use heat and chemicals to extract lithium from rock produce significant amounts of harmful waste.

Researchers led by James Tour, the T.T. and W.F. Chao Professor of Chemistry and professor of materials science and nanoengineering at Rice University, have developed a faster and cleaner method using flash Joule heating (FJH). This technique rapidly heats materials to thousands of degrees within milliseconds and works in conjunction with chlorine gas, exposing the rock to intense heat and chlorine gas, they can quickly convert spodumene ore into usable lithium.

Cryo-imaging gives deeper view of thick biological materials

Electron microscopy is an exceptional tool for peering deep into the structure of isolated molecules. But when it comes to imaging thicker biological samples to understand how those molecules function in their cellular environments, the technology gets a little murky.

Cornell researchers devised a new method, called tilt-corrected bright-field scanning transmission electron microscopy (tcBF-STEM), to image thick samples with higher contrast and a fivefold increase in efficiency.

The Sept. 23 publication of the findings, in Nature Methods, arrives two years after the death of co-author Lena Kourkoutis, M.S. ‘06, Ph.D. ‘09, associate professor in applied and in Cornell Engineering, whose work in cryo-electron microscopy drove much of the nearly 10-year effort.

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