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Blood Test #2 In 2026: Biological Age, CVD Risk, Correlations With Diet

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Discount Links/Affiliates:
Blood testing (where I get the majority of my labs, for those who blood test with Quest): https://www.ultalabtests.com/partners… those who blood test with LabCorp: https://www.anrdoezrs.net/click-10161… At-Home Metabolomics: https://www.iollo.com?ref=michael-lus… Use Code: CONQUERAGING At Checkout Clearly Filtered Water Filter: https://get.aspr.app/SHoPY Epigenetic, Telomere Testing: https://trudiagnostic.com/?irclickid=… Use Code: CONQUERAGING NAD+ Quantification: https://www.jinfiniti.com/intracellul… Use Code: ConquerAging At Checkout Oral Microbiome: https://www.bristlehealth.com/?ref=mi… Enter Code: ConquerAging SiphoxHealth Blood Testing (ApoB, GrimAge): https://siphoxhealth.com/mlustgarten Green Tea: https://www.ochaandco.com/?ref=fqbtflod Use Code: ML10OFF Diet Tracking: https://shareasale.com/r.cfm?b=139013… If you’d like to support the channel, you can do that with the website, Buy Me A Coffee: https://www.buymeacoffee.com/mlhnrca Conquer Aging Or Die Trying Merch! https://my-store-d4e7df.creator-sprin…

Blood Testing Essentials (Biological Age, CVD-Risk, Kidney Health and Function):
PhenoAge (Biological Age): https://www.ultalabtests.com/partners…

Risk-weighted ApoB (a better CVD predictor than LDL, non-HDL cholesterol, and ApoB): https://www.ultalabtests.com/partners…

Kidney health and function: https://www.ultalabtests.com/partners…

Dr. Stuart Hameroff: Consciousness is More than Computation!

13 years ago, I walked into Dr. Stuart Hameroff’s operating room with a camera, a microphone, and a single stubborn question:

Is consciousness computation?

Hameroff, an anesthesiologist and professor at the University of Arizona, and co-author with Sir Roger Penrose of the Orch OR theory, said no.

Emphatically. Unfashionably. Against the entire weight of mainstream neuroscience and Silicon Valley orthodoxy.

At the GF2045 conference, where I first met him, Ray Kurzweil went out of his way to declare Orch OR “totally wrong.” Others called it speculative. Untestable. Unscientific.

Today, in the age of large language models, that argument is no longer a niche dispute among philosophers and physicists. It is the decisive question of our century.

Continue reading “Dr. Stuart Hameroff: Consciousness is More than Computation!” | >

Optical meta‑conveyors enable programmable nanomanipulation along arbitrary open paths

The task of gently transporting a microscopic particle from one point to another along a winding path, and then bringing it back using nothing more than a single, compact chip is a challenge we set out to address in our new study, now published in Nature Communications.

Optical forces arising from momentum exchange during light–matter interactions have become indispensable tools in biophysics, soft matter science and micro-and nanofabrication. Among these, optical conveyors—capable of generating stable, directional optical flows—enable nanoparticle transport along predefined trajectories, offering unique advantages for drug delivery, cell sorting, and lab-on-a-chip systems. However, conventional platforms often rely on spatial light modulators to produce dynamic holograms. Such systems are bulky, constrained by limited pixel size and count, and difficult to integrate—factors that severely impede practical deployment.

Metasurfaces have recently opened new pathways for miniaturizing optical manipulation devices, thanks to their subwavelength field-shaping capabilities. Yet, most existing metasurface-based schemes still depend on radially or azimuthally uniform phase gradients, which confine the resulting optical flow to closed loops (vortex rings) due to the intrinsic geometry of vortex fields.

Functional Reorganization of Corticostriatal Connectivity Across the Degree of Nigrostriatal Degeneration in Parkinson Disease

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Scientists recruit red blood cells to deliver genetic cargo with instructions to kill cancer

Scientists have developed a way to turn the body’s own immune cells into cancer-fighting agents—without removing them from the body—by using red blood cells to deliver genetic instructions. Current CAR (chimeric antigen receptor) therapies typically involve collecting a patient’s T cells, genetically modifying them in the laboratory, and then reinfusing them in a process that can take weeks. The new strategy aims to bypass that step.

In a study published in Science Translational Medicine, researchers at Westlake Laboratory of Life Sciences and Biomedicine in Hangzhou, China, report that they used engineered erythrocytes, or red blood cells, to carry messenger RNA—mRNA—that reprograms myeloid cells into tumor-targeting cells inside the body.

“Engineering myeloid cells with chimeric antigen receptors—CARs—holds great therapeutic promise,” writes Dr. Xiaoqian Nie, lead author of the investigation.

Meet The Axolotl — The Salamander That Can Regrow Its Own Brain

But over evolutionary time, mammals have obviously lost the vast majority of this regenerative capacity. Instead, evolution opted for faster wound sealing, stronger immune responses and more stable neural systems in mammals. This is likely because surviving injury would have mattered more than perfectly reconstructing tissue months later.

Salamanders, on the other hand, have retained far more of this ancestral regenerative toolkit. Their ecology may have reinforced this retention, since small amphibians are especially vulnerable to predation and environmental injury. Limbs, tails and nervous tissue can be damaged surprisingly easily in aquatic habitats filled with predators, debris, and competition. For an animal living close to the edge of survival, the ability to recover from catastrophic injury could dramatically improve reproductive success.

The axolotl’s strange life history has most probably also enabled this unique ability. Unlike many amphibians, axolotls remain in a juvenile-like aquatic state throughout adulthood, a phenomenon known as “neoteny.” Intriguingly, juvenile tissues in many vertebrates tend to be more regenerative than adult tissues. Thus, by retaining aspects of its developmental state for life, the axolotl may preserve cellular programs that would otherwise be “switched off” after maturation.

New recyclable protein textiles could cut microplastic pollution and lower clothing waste

The textile industry produces a substantial portion of the world’s waste, with only about 12% of fiber materials ending up in recycling. Textiles also account for much of the microplastics in oceans. During every wash cycle, synthetic fibers shed microplastics that are flushed down the drain and eventually enter aquatic environments. Increasing textile recycling alone won’t solve this problem because most petrochemical-based fibers are difficult to recycle and continue to release persistent microplastics throughout their life cycle.

Engineers from Washington University in St. Louis may have a solution, thanks to dedicated synthetic biology work in the lab of Fuzhong Zhang, the Francis F. Ahmann Professor in the Department of Energy, Environmental & Chemical Engineering in the McKelvey School of Engineering and co-director of Synthetic Biology Manufacturing of Advanced Materials Research Center (SMARC).

The results of that work, now published in the journal Advanced Materials, created protein-based materials, which are produced in bioreactors (think giant brewing tanks) using genetically engineered microbes. These materials can be readily recycled after use and remade into the same fibers over multiple cycles. In addition, any microparticles, if released from these fibers during washing, would be biodegradable.

Hidden small RNA in cholera bacterium helps determine whether it can infect humans

Scientists from St. Jude Children’s Research Hospital have uncovered what gives Vibrio cholerae, the bacterium that causes cholera, the ability to colonize the human gut. The researchers found that a small RNA embedded within another gene controls where cholera thrives, a discovery that could improve prediction and prevention strategies. The study is published in the journal Nature Communications.

Infectious diseases remain the leading cause of pediatric mortality worldwide. V. cholerae causes a severe diarrheal disease leading to more than 143,000 deaths and millions of cases each year, primarily affecting young children. While there are many strains of the V. cholerae species, only one can infect humans. The reason for this has been unclear for 50 years, hampering efforts to predict and prevent outbreaks.

“For decades, we’ve been trying to understand what allows cholera to infect humans,” said corresponding author Salvador Almagro-Moreno, Ph.D., St. Jude Department of Host-Microbe Interactions. “The answer was right in front of us the whole time—this small RNA hiding inside another gene is the real culprit.”

Scientists discover tiny gut particles that may drive aging and chronic disease

A new study suggests microscopic particles from the gut may actively drive inflammation and chronic diseases associated with aging. Remarkably, gut particles from young animals appeared to counter some aging-related damage in older animals, hinting at new possibilities for future treatments.

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