Lifeboat Foundation

Researchers from North Carolina State University have identified a microRNA (miRNA) that could promote hair regeneration. This miRNA – miR-218-5p – plays an important role in regulating the pathway involved in follicle regeneration, and could be a candidate for future drug development.

Hair growth depends on the health of dermal papillae (DP) cells, which regulate the hair follicle growth cycle. Current treatments for hair loss can be costly and ineffective, ranging from invasive surgery to chemical treatments that don’t produce the desired result. Recent hair loss research indicates that hair follicles don’t disappear where balding occurs, they just shrink. If DP cells could be replenished at those sites, the thinking goes, then the follicles might recover.

A research team led by Ke Cheng, Randall B. Terry, Jr. Distinguished Professor in Regenerative Medicine at NC State’s College of Veterinary Medicine and professor in the NC State/UNC Joint Department of Biomedical Engineering, cultured DP cells both alone (2D) and in a 3D spheroid environment. A spheroid is a three-dimensional cellular structure that effectively recreates a cell’s natural microenvironment.

Crystal engineering is a green and convenient approach to designing desirable materials through rational manipulation of intermolecular interactions. We have reported the lesser reported sulfonate–pyridinium intermolecular interaction for the design and synthesis of organic co-crystals with improved features. Here in we report the utilization of the interaction to tune the solid-state luminescence of organic precursor naphthalene disulfonic acid (NDSA-2H). Organic salts of NDSA-2H are synthesized and characterized with three isostructural bipyridyl co-formers: 4-phenylpyridine (4-PhPy), 2-phenylpyridine (2-PhPy) and 2,2′-bipyridine (2,2-bpy). Structural investigation validates aggregation of organic acid and base co-formers through sulfonate–pyridinium synthon and proton transfer between them.

It took Da Vinci 16 years to paint the Mona Lisa. Some say he needed 12 years just to paint her lips.

There is no truth to the rumors that slow Internet was the cause.

But Da Vinci, a polymath who dabbled in botany, engineering, science, sculpture, and geology as well as painting, surely would have appreciated a new text-to-image generative vision transformer developed by Google Research.

Kairan Quazi announced the news in an impressive LinkedIn post, during which he explained how he’d begun his software engineering career at an early age.

While he kept post pretty professional, Quazi couldn’t help but gush about working for the ‘coolest company on the planet’.

Kairan Quazi is only in his teens, but has already graduated with a computer science degree before accepting a job with SpaceX.

Continue reading “Child prodigy accepts job offer from SpaceX after graduating at just 14” »

Cancer remains one of the leading causes of death in the US at over 600,000 deaths per year. Cancers that form solid tumors such as in the breast, brain, or skin are particularly hard to treat. Surgery is typically the first line of defense for patients fighting solid tumors. But surgery may not remove all cancerous cells, and leftover cells can mutate and spread throughout the body. A more targeted and wholistic treatment could replace the blunt approach of surgery with one that eliminates cancer from the inside using our own cells.

Dennis Discher, Robert D. Bent Professor of Chemical and Biomolecular Engineering, and postdoctoral fellow Larry Dooling provide a new approach in targeted therapies for solid tumor cancers in their study, published in Nature Biomedical Engineering. Their therapy not only eliminates cancerous cells, but teaches the immune system to recognize and kill them in the future.

Scientists have taken a significant step forward in the study of the properties of quarks and gluons, the particles that make up atomic nuclei, by resolving a long-standing issue with a theoretical calculation method known as “axial gauge.” MIT

MIT is an acronym for the Massachusetts Institute of Technology. It is a prestigious private research university in Cambridge, Massachusetts that was founded in 1861. It is organized into five Schools: architecture and planning; engineering; humanities, arts, and social sciences; management; and science. MIT’s impact includes many scientific breakthroughs and technological advances. Their stated goal is to make a better world through education, research, and innovation.

The experiments are the first of their kind and could lead to new advances in computing.

A team at the University of Chicago.

Founded in 1,890, the University of Chicago (UChicago, U of C, or Chicago) is a private research university in Chicago, Illinois. Located on a 217-acre campus in Chicago’s Hyde Park neighborhood, near Lake Michigan, the school holds top-ten positions in various national and international rankings. UChicago is also well known for its professional schools: Pritzker School of Medicine, Booth School of Business, Law School, School of Social Service Administration, Harris School of Public Policy Studies, Divinity School and the Graham School of Continuing Liberal and Professional Studies, and Pritzker School of Molecular Engineering.

The latest recruit at SpaceX is a software engineer who passed its “technically challenging” and “fun” interview process.

What’s different about Kairan Quazi is that he’s just 14 years old.

He said in a LinkedIn post on Thursday: “I will be joining the coolest company on the planet as a software engineer on the Starlink engineering team. One of the rare companies that did not use my age as an arbitrary and outdated proxy for maturity and ability.”

One might say that C was replaced by C++, which was later replaced by Python. Now we have prompt engineering to replace Python.