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A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson’s disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis School of Gerontology study.

The variant, located in a mitochondrial microprotein dubbed SHLP2, was found to be highly protective against Parkinson’s disease; individuals with this mutation are half as likely to develop the disease as those who do not carry it. The variant form of the protein is relatively rare and is found primarily in people of European descent.

The findings appear in the journal Molecular Psychiatry.

A new artificial intelligence tool that interprets medical images with unprecedented clarity does so in a way that could allow time-strapped clinicians to dedicate their attention to critical aspects of disease diagnosis and image interpretation.

The tool, called iStar (Inferring Super-Resolution Tissue Architecture), was developed by researchers at the Perelman School of Medicine at the University of Pennsylvania, who believe they can help clinicians diagnose and better treat cancers that might otherwise go undetected.

The imaging technique provides both highly detailed views of individual cells and a broader look at the full spectrum of how people’s genes operate, which would allow doctors and researchers to see cancer cells that might otherwise have been virtually invisible. This tool can be used to determine whether safe margins were achieved through cancer surgeries and automatically provide annotation for microscopic images, paving the way for molecular disease diagnosis at that level.

CryocrastinationDescription: Biostasis techniques such as cryopreservation, which allow recently-living organisms to be stored indefinitely without deteriora…

PRESS RELEASE — Scientists are working on a new device that could lead to a reduction in the number of people who go blind from age-related macular degeneration (AMD). Researchers at Centre for Eye and Vision Research (CEVR) are using quantum technology to detect the disease in its early stages where treatment may help preserve vision.

As part of a visit during the recent Hong Kong Laureate Forum, young scientists from across the world learned how the new low-cost ophthalmic diagnostic device could be part of routine GP and outpatient check-ups.

AMD which affects more than 200 million people worldwide, causes changes to the macula, which can lead to problems with central, detailed vision.

Is critical for digital transformation, but when #mistrust in change is as endemic as change itself, we need to dig deeper to build capacity. #wef24

From Facebook founder to “girl dad” to cattle rancher to doomsday prepper, Meta CEO Mark Zuckerberg seemingly has it all.

Potentially good technology if it makes it to market. A new semiconductor would be great!

Researchers at the Georgia Institute for Technology have found a new semiconductor that’s a really good candidate for making computers faster and smaller than ever. Amazingly enough, it works by combining graphene with silicon carbide, to give a material with a sensible band gap that still has a high thermal conductivity.

Continue reading “This New Semiconductor Could Revolutionize Computing” »

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Manolis Kellis, an accomplished Computer Science Professor at MIT and member of the Broad Institute, is a trailblazer in computational biology. Renowned for leading the MIT Computational Biology Group, his impactful research spans disease genetics, epigenomics, and gene circuitry. With numerous cited publications and leadership in transformative genomics projects, Kellis has garnered prestigious accolades, including the PECASE and Sloan Fellowship, shaping the field with his international perspective from Greece and France to the US.

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Continue reading “Curing Disease With Genetics And AI” »