Lifeboat Foundation

In a global research effort, scientists have uncovered a relationship between metabolism problems in the brain and a range of neuropsychiatric and neurodegenerative disorders, from autism to Alzheimer’s disease and more.

Despite their diverse symptoms, these conditions – as well as depression, epilepsy, schizophrenia, intellectual disability, and bipolar disorder – all involve a degree of cognitive impairment and often share genetic or metabolic features, hinting at a common biological basis.

The extensive collaboration by the International Brain pH Project Consortium, involving 131 scientists from 105 labs in seven countries, identified changes in brain acidity and lactate levels in animals as key signs of this metabolic dysfunction.

A non-radical proximity labelling platform — BAP-seq — is presented that uses subcellular-localized BS2 esterase to convert unreactive enol-based probes into highly reactive acid chlorides in situ to label nearby RNAs. When paired with click-handle-mediated enrichment and sequencing, this chemistry enables high-resolution spatial mapping of RNAs across subcellular compartments.

Researchers reveal that naturally emerging epsilon-near-zero conditions in BaTiO3 can be exploited to drive permanent all-optical switching of ferroelectric polarization. The general nature of the epsilon-near-zero regime means that the approach could be used to switch spontaneous order parameters in other systems.

Could our First Alien Contact be with Intelligent Spiders as in the SciFi novel “Children of Time”? New blog posted on BigThink, link at https://www.searchforlifeintheuniverse.com/post/could-our-fi…nt-spiders

The Biden administration plans to announce awarding more than $6 billion to Samsung to expand its chip output in Texas, two sources said.

Dark matter is a ghostly substance that astronomers have failed to detect for decades, yet which we know has an enormous influence on normal matter in the universe, such as stars and galaxies. Through the massive gravitational pull it exerts on galaxies, it spins them up, gives them an extra push along their orbits, or even rips them apart.

Like a cosmic carnival mirror, it also bends the light from distant objects to create distorted or multiple images, a process which is called gravitational lensing.

And recent research suggests it may create even more drama than this, by producing stars that explode.

Researchers have successfully transformed CO₂ into methanol by shining sunlight on single atoms of copper deposited on a light-activated material, a discovery that paves the way for creating new green fuels.

An international team of researchers from the University of Nottingham’s School of Chemistry, University of Birmingham, University of Queensland, and University of Ulm have designed a material made up of copper anchored on nanocrystalline carbon nitride.

The copper atoms are nested within the nanocrystalline structure, which allows electrons to move from carbon nitride to CO₂, an essential step in the production of methanol from CO₂ under the influence of solar irradiation. The research has been published in the Sustainable Energy & Fuels journal.

In a revolutionary scientific endeavor, researchers are using 5,000 miniature robots perched atop a mountaintop telescope to peer an astonishing 11 billion years into the past. This cutting-edge instrument, known as the Dark Energy Spectroscopic Instrument (DESI), is capturing light from distant objects in space, allowing scientists from the Lawrence Berkeley National Laboratory to map our cosmos as it was in its infancy and trace its evolution to the present day.

Why is this so important? Understanding how our universe has evolved is intrinsically linked to predicting its ultimate fate and unraveling one of the biggest mysteries in physics: dark energy. This enigmatic force is causing our universe to expand at an ever-increasing rate, and DESI is providing us with unprecedented insights into its effects over the past 11 billion years.

Continue reading “5,000 Tiny Robots Unveil Secrets Of Universe’s Dark Energy” »

The medical breakthrough will have to wait a bit longer.