Lifeboat Foundation

“Preserve health, prevent disease, prolong healthspan,” begins the mission statement of the Kitalys Institute. Lofty goals indeed from the not-for-profit organisation behind the annual Targeting Metabesity conference and a range of initiatives to translate longevity science into genuine public health gains.

Longevity. Technology: The vast majority of companies developing therapeutics in the longevity field are adopting strategies that involve targeting specific indications rather than aging itself. And well they might, because there is currently no precedent for drugs targeting aging at regulatory bodies like the FDA. Kitalys wants to change that, and we caught up with the institute’s founder Dr Alexander “Zan” Fleming to find out more.

An endocrinologist by training, Fleming is well qualified to take on the regulators. He spent more than a decade at the FDA, where he led the medical reviews that resulted in approval of drugs including metformin, as well as the first statin, insulin analogue and PPAR agonist.

Scientists have discovered a new type of brain cell that promises to shake up the field of neuroscience.

The discovery brings an end to a decades-old controversy and may pave the way for new targeted treatments for a range of health conditions.

The 10,000-square-foot lab space is the first off-campus site for the university’s Discovery to Impact program.

For now, cyborgs exist only in fiction, but the concept is becoming more plausible as science progresses. And now, researchers are reporting in ACS’ Nano Letters that they have developed a proof-of-concept technique to “tattoo” living cells and tissues with flexible arrays of gold nanodots and nanowires. With further refinement, this method could eventually be used to integrate smart devices with living tissue for biomedical applications, such as bionics and biosensing.

Advances in electronics have enabled manufacturers to make integrated circuits and sensors with nanoscale resolution. More recently, laser printing and other techniques have made it possible to assemble flexible devices that can mold to curved surfaces. But these processes often use harsh chemicals, high temperatures or pressure extremes that are incompatible with living cells. Other methods are too slow or have poor spatial resolution. To avoid these drawbacks, David Gracias, Luo Gu and colleagues wanted to develop a nontoxic, high-resolution, lithographic method to attach nanomaterials to living tissue and cells.

The team used nanoimprint lithography to print a pattern of nanoscale gold lines or dots on a polymer-coated silicon wafer. The polymer was then dissolved to free the gold nanoarray so it could be transferred to a thin piece of glass. Next, the gold was functionalized with cysteamine and covered with a hydrogel layer, which, when peeled away, removed the array from the glass. The patterned side of this flexible array/hydrogel layer was coated with gelatin and attached to individual live fibroblast cells. In the final step, the hydrogel was degraded to expose the gold pattern on the surface of the cells. The researchers used similar techniques to apply gold nanoarrays to sheets of fibroblasts or to rat brains. Experiments showed that the arrays were biocompatible and could guide cell orientation and migration.

To check out any of the lectures available from Great Courses Plus go to http://ow.ly/dweH302dILJ

We’ll soon be capable of building self-replicating robots. This will not only change humanity’s future but reshape the galaxy as we know it.

Continue reading “Self-Replicating Robots and Galactic Domination” »

From AI to AGI — witness the evolution. This video unpacks the intricate differences between AI and Artificial General Intelligence, shedding light on their roles in the Fourth Industrial Revolution. Explore the fascinating journey from specialized AI systems to the broad adaptability of AGI. Plus, catch a glimpse of what the future holds as we discuss the synergy between AI and AGI in modern tech.

Make sure your battery doesn’t die while watching these videos.
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Continue reading “AI vs. AGI: The Great Intelligence Divide Explained” »

The density of neurons in the brain is governed by a fundamental mathematical function, new research finds.

The discovery, which holds true across a variety of mammals, could help researchers make better computer models of the brain in the future.

Year 2022 femtosecond logic gates for computers once thought to be almost a myth only for 2099 dreams is now real.

Light-field control of real and virtual charge carriers in a gold–graphene–gold heterostructure is demonstrated, and used to create a logic gate for application in lightwave electronics.

Year 2015 Once again nature shows intelligent design so advanced that it can leave us in awe. I personally never thought that an infinite logic gate was possible due to the nature of the speed of it or that it would create a gravity well or something weird but here it is an infinite logic gate 😗😁😘.

Scientific Reports — An organic jelly made fractal logic gate with an infinite truth table. Sci. Rep. 5, 11265; doi: 10.1038/srep11265 (2015).