Lifeboat Foundation

Gene therapy may be the best hope for curing retinitis pigmentosa (RP), an inherited condition that usually leads to severe vision loss and blinds 1.5 million people worldwide.

But there’s a huge obstacle: RP can be caused by mutations in over 80 different genes. To treat most RP patients with gene therapy, researchers would have to create a therapy for each gene—a nearly impractical task using current gene therapy strategies.

A more universal treatment may be forthcoming. Using CRISPR-based genome engineering, scientists at Columbia University Vagelos College of Physicians and Surgeons are designing a gene therapy with the potential to treat RP patients regardless of the underlying genetic defect.

Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain—a process that drives cognitive decline in Alzheimer’s disease and frontotemporal dementia. This new model has led to the identification of novel therapeutic targets that could potentially block tau spread.

An automated counterflow centrifugation–based technology outperforms manual peripheral blood mononuclear cell (PBMC) isolation.

A solid-state battery developer in China has unveiled a new cell that could help change the game for electric mobility. Tailan New Energy’s vehicle-grade all-solid-state lithium batteries offer energy density twice that of other cells in the segment, empowering the Chinese battery maker to hail the cells as a record-setter in the industry.

Tailan New Energy, aka Talent New Energy, is a private solid-state battery developer founded in Beijing, China, in 2018, where it remains headquartered in its research.

Per its website, it was “co-founded by lithium battery R&D experts and a senior domestic industrialization team, focusing on the technological development and industrialization of new solid-state lithium batteries and key lithium battery materials.”

The upcoming entry-level Mercedes-Benz EV dubbed the “one-liter car” for its long-range capabilities, was finally caught out in the wild. In a new video, the electric Mercedes CLA was spotted testing near the Arctic Circle. The new EV is Mercedes-Benz’s answer to the Tesla Model 3.

Mercedes unveiled the electric CLA Concept in September, the first model in a new series of entry-level EVs.

Continue reading “Mercedes-Benz’s sleek new entry-level CLA EV spotted as a Tesla Model 3 rival [Video]” »

Apple is exploring various “personal robotics” projects in an effort to create its “next big thing,” according to Bloomberg’s Mark Gurman.

Amazon’s Astro robot

One of these projects is described as a “mobile robot” that would “follow users around their homes,” while another is said to be an “advanced table-top home device that uses robotics to move a display around”:

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Discover AI school safety solutions with security technology from Xtract One. Protect your educational institution with cutting-edge threat detection solutions.

As electric vehicle sales slow, Colorado wants the new faster-charging stations to serve as an answer to consumer “range anxiety.”