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Sep 25, 2023

Another class of cancer drugs may contribute to curing HIV

Posted by in categories: biotech/medical, genetics

Two drugs from a class new to HIV medicine called BH3 mimetics were unveiled at July’s 12th International AIDS Society Conference on HIV Science (IAS 2023) in Brisbane. They may contribute to a cure for HIV by killing off long-lived cells that contain HIV genes in their DNA. Notably, venetoclax (Venclexta) and obatoclax only killed off cells containing intact DNA, capable of giving rise to new viruses, and did not delete cells containing defective, harmless DNA.

A number of drugs and treatments from the anti-cancer arsenal have been investigated as HIV cure research such as HDAC inhibitors, PD-1 inhibitors and therapeutic vaccines. (And, of course, the six successful cures so far have used the radical cancer therapy of a stem cell (bone marrow) transplant.)

This is not coincidental: cancer and AIDS are both the end result of mutations in the DNA of some of our cells. In the case of cancer they arise in the host DNA and in HIV infection they are introduced by a virus, but both are the result of ‘rogue genes’ (some other viruses, such as HPV, directly cause cancers).

Sep 24, 2023

Controlling Devices with Thought, No Open Brain Surgery Required

Posted by in categories: biotech/medical, computing, neuroscience

Synchron has developed a Brain-Computer Interface that uses pre-existing technologies such as the stent and catheter to allow insertion into the brain without the need for open brain surgery.

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Sep 24, 2023

Artificial Intelligence in Brain Tumour Surgery—An Emerging Paradigm

Posted by in categories: biotech/medical, robotics/AI

Artificial intelligence (AI) is the branch of computer science that enables machines to learn, reason, and problem solve. In recent decades, AI has been developed with the aim of improving the management of patients with brain tumours. This review article explores the role AI currently plays in managing patients undergoing brain tumour surgery, and explores how AI may impact this field in the future.

Artificial intelligence (AI) platforms have the potential to cause a paradigm shift in brain tumour surgery. Brain tumour surgery augmented with AI can result in safer and more effective treatment. In this review article, we explore the current and future role of AI in patients undergoing brain tumour surgery, including aiding diagnosis, optimising the surgical plan, providing support during the operation, and better predicting the prognosis. Finally, we discuss barriers to the successful clinical implementation, the ethical concerns, and we provide our perspective on how the field could be advanced.

Keywords: artificial intelligence, AI, neurosurgery, brain tumour, machine learning, deep learning, surgery, oncology.

Sep 24, 2023

AI can help to speed up drug discovery — but only if we give it the right data

Posted by in categories: biotech/medical, robotics/AI

Artificial-intelligence tools that enable companies to share data about drug candidates while keeping sensitive information safe can unleash the potential of machine learning and cutting-edge lab techniques, for the common good.

Sep 24, 2023

Hauser PI on $1.2 million grant to expand and refine robotic eye examination system

Posted by in categories: biotech/medical, health, robotics/AI

A collaboration between researchers at the University of Illinois Urbana-Champaign and Duke University has developed a robotic eye examination system, and the National Institutes of Health has awarded the researchers $1.2 million to expand and refine the system.

The researchers have developed a robotic system that automatically positions examination sensors to scan human eyes. It currently uses an optical scan technique which can operate from a reasonably safe distance from the eye, and now the researchers are working to add more features that will help it perform most steps of a standard eye exam. These features will require the system to operate in closer proximity to the eye.

“Instead of having to spend time in a doctor’s office going through the manual steps of routine examinations, a robotic system can do this automatically,” said Kris Hauser, a U. of I. computer science professor and the study’s principal investigator. “This would mean faster and more widespread screening leading to better health outcomes for more people. But to achieve this, we need to develop safer and more reliable controls, and this award allows us to do just that.”

Sep 24, 2023

HPV Vaccination in India : New Progress and the way forward

Posted by in category: biotech/medical

In a promising advance in its fight against cervical cancer, India recently launched its first locally produced version of the human papillomavirus (HPV) vaccine “Cervavac”. Currently, India lacks a national immunization program for carcinoma cervix eradication. Inclusion of Cervavac into the national immunization schedule will undoubtedly boost the fight against cervical cancer.

HPV is a group of more than 200 related viruses, sexually transmitted HPV types fall into two groups, low risk and high risk. High-risk HPVs can cause several types of cancer. HPV infection is common. Nearly all sexually active people are infected with HPV within months to a few years of becoming sexually active. Most HPV infections don’t cause cancer. Our immune system usually clears most of HPV infections. Only about 1% of High-risk HPV infections that persist can cause cancer. Human papillomavirus (HPV) infection is a well-established cause of cervical cancer and there is growing evidence of HPV being an important factor in other anogenital cancers (anus, vulva, vagina, and penis) as well as head and neck cancers.

Sep 24, 2023

Tesla releases update on Optimus robot with video looking like CGI

Posted by in categories: Elon Musk, robotics/AI

Tesla has released an update with progress on its Optimus humanoid robot with a video that almost looks like CGI.

Optimus, also known as Tesla Bot, has not been taken seriously by many outside of the more hardcore Tesla fans, and for good reasons.

When it was first announced, it seemed to be a half-baked idea from CEO Elon Musk with a dancer disguised as a robot for visual aid. It also didn’t help that the demo at Tesla AI Day last year was less than impressive.

Sep 24, 2023

Jaguar signs deal with Tesla for Supercharger access, will adopt NACS

Posted by in category: transportation

Jaguar announced that it has signed a deal with Tesla to get access to the Supercharger network. The British automaker also agreed to adopt the Tesla-designed NACS connector in North America.

The NACS domino effect has been in full force for the past few months.

After Ford and GM announced that they will be adopting Tesla’s newly opened and renamed connector standard, NACS, other automakers have been rushing to make deals with Tesla to access the Supercharger network as part of a transition to the new connector.

Sep 24, 2023

Tesla’s MIND-BLOWING FSD V.12 Elon Musk Demo | Self-Driving Tesla

Posted by in categories: Elon Musk, media & arts, robotics/AI, transportation

Teslas full-self driving Version 12 has just shocked the World. Elon Musk live-streamed it’s capabilities for the first time, and detailed how it now operates compared to previous versions of Teslas FSD. This really is a mind-blowing moment for Tesla, Tesla owners, and the future of Autonomous Cars.

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Sep 24, 2023

NASA’s First Asteroid Sample Has Landed, Now Secure in Clean Room

Posted by in categories: chemistry, security, space

After years of anticipation and hard work by NASA’s OSIRIS-REx (Origins, Spectral Interpretation, Resource Identification and Security – Regolith Explorer) team, a capsule of rocks and dust collected from asteroid Bennu finally is on Earth. It landed at 8:52 a.m. MDT (10:52 a.m. EDT) on Sunday, in a targeted area of the Department of Defense’s Utah Test and Training Range near Salt Lake City.

Within an hour and a half, the capsule was transported by helicopter to a temporary clean room set up in a hangar on the training range, where it now is connected to a continuous flow of nitrogen.

Getting the sample under a “nitrogen purge,” as scientists call it, was one of the OSIRIS-REx team’s most critical tasks today. Nitrogen is a gas that doesn’t interact with most other chemicals, and a continuous flow of it into the sample container inside the capsule will keep out earthly contaminants to leave the sample pure for scientific analyses.