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Archive for the ‘biotech/medical’ category: Page 85

Oct 25, 2023

A next-generation treatment for bile duct cancer

Posted by in category: biotech/medical

FGFR inhibitors, in combination with standard treatments, have extended the lives of many with this disease. However, these drugs often stop working after six to eight months.

“These drugs work very well for a while, but resistance is inevitable,” says gastrointestinal medical oncologist Milind Javle, M.D.

Now, a new type of FGFR inhibitor may allow patients to live longer without their disease progressing.

Oct 25, 2023

Robots learn faster with AI boost from Eureka

Posted by in categories: biotech/medical, drones, robotics/AI, security

Intelligent robots are reshaping our universe. In New Jersey’s Robert Wood Johnson University Hospital, AI-assisted robots are bringing a new level of security to doctors and patients by scanning every inch of the premises for harmful bacteria and viruses and disinfecting them with precise doses of germicidal ultraviolet light.

In agriculture, robotic arms driven by drones scan varying types of fruits and vegetables and determine when they are perfectly ripe for picking.

The Airspace Intelligence System AI Flyways takes over the challenging and often stressful tasks of flight dispatchers who must make last-minute flight pattern changes due to sudden extreme weather, depleted fuel supplies, mechanical problems or other emergencies. It optimizes solutions, is safer, saves time and is cost-efficient.

Oct 24, 2023

Norepinephrine Chemistry’s Electrical Signals Tracked in Conscious Human Brains

Posted by in categories: biotech/medical, chemistry, health, neuroscience

The results of a human study carried out by an international research team have provided valuable new insights into the activity of the brain’s noradrenaline (NA) system, which has been a longtime target for medications to treat attention-deficit/hyperactivity disorder, depression, and anxiety. The study employed what the researchers claim is a groundbreaking methodology, developed to record real-time chemical activity from standard clinical electrodes implanted into the brain routinely for epilepsy monitoring.

The results offer up new insights into brain chemistry, which could have implications for a wide array of medical conditions, and also demonstrate use of the new strategy for acquiring data from the living human brain.

“Our group is describing the first ‘fast’ neurochemistry recorded by voltammetry from conscious humans,” said Read Montague, PhD, the VTC Vernon Mountcastle research professor at Virginia Tech, and director of the Center for Human Neuroscience Research and the Human Neuroimaging Laboratory of the Fralin Biomedical Research Institute at VTC. “This is a big step forward and the methodological approach was implemented completely in humans – after more than 11 years of extensive development.” Montague is senior, and co-corresponding author of the researchers’ published paper in Current Biology, which is titled “Noradrenaline tracks emotional modulation of attention in human amygdala.” In their paper the authors concluded, “By showing that neuromodulator estimates can be obtained from depth electrodes already in standard clinical use in the conscious human brain, our study opens the door to a new area of research on the neuromodulatory basis of human health and disease.”

Oct 24, 2023

Diabetes: Eye implant could deliver cell-based treatment

Posted by in category: biotech/medical

A microscopic, stitch-free eye implant may be used to treat both type 1 and tyoe 2 diabetes and other diseases, a new study suggests.

Oct 24, 2023

Newly Found Pandoraviruses Hint at a Fourth Branch of Life

Posted by in categories: bioengineering, biotech/medical, food

This exemplary virus makes its own genes which many have theories say that it could be a direct relationship to the sorta alien ant farm we are currently in on earth. That maybe it is a clue that viruses started all life from a sorta panspermia whether it was from meteorites or even direct gene engineering from aliens this virus gives us a clue even to our evolutionary processes that we could even become aliens someday.


Pandoraviruses, the largest viruses ever found, are shaking up the tree of life. Could they and other abnormally large viruses belong to a fourth branch of life separate from Bacteria, Archaea, and Eukaryotes?

Oct 24, 2023

The viruses that helped to make you human

Posted by in categories: biotech/medical, evolution

Although they are more commonly associated with causing disease and, at times, devastating pandemics, viruses have also played an important role in human evolution.

Oct 24, 2023

Researchers create magnetic microrobots that work together to assemble objects in 3D environments

Posted by in categories: biotech/medical, robotics/AI

For the first time ever, researchers at the Surgical Robotics Laboratory of the University of Twente successfully made two microrobots work together to pick up, move and assemble passive objects in 3D environments. This achievement opens new horizons for promising biomedical applications.

Imagine you need surgery somewhere inside your body. However, the part that needs surgery is very difficult for a surgeon to reach. In the future, a couple of robots smaller than a grain of salt might go into your body and perform the surgery. These microrobots could work together to perform all kinds of complex tasks. “It’s almost like magic,” says Franco Piñan Basualdo, corresponding author of the publication.

Researchers from the University of Twente successfully exploited two of these 1-millimeter-sized magnetic microrobots to perform several operations. Like clockwork, the microrobots were able to pick up, move and assemble cubes. Unique to this achievement is the 3D environment in which the robots performed their tasks.

Oct 24, 2023

Spectacular Vision: Physicists Boost Microscopes Beyond Diffraction Limits

Posted by in category: biotech/medical

New technique could be used in medical diagnostics and advanced manufacturing.

Ever since Antonie van Leeuwenhoek discovered the world of bacteria through a microscope in the late seventeenth century, humans have tried to look deeper into the world of the infinitesimally small.

There are, however, physical limits to how closely we can examine an object using traditional optical methods. This is known as the ‘diffraction limit’ and is determined by the fact that light manifests as a wave. It means a focused image can never be smaller than half the wavelength of light used to observe an object.

Oct 24, 2023

AI-based MRI tools show promise in multiple sclerosis diagnosis

Posted by in categories: biotech/medical, robotics/AI

A groundbreaking study in NPJ Digital Medicine demonstrates the superior accuracy of AI-based imaging in diagnosing and monitoring multiple sclerosis.

Oct 23, 2023

Tucatinib plus Trastuzumab Effective in HER2+ Biliary Cancer

Posted by in categories: biotech/medical, chemistry

Next generation sequencing is now essential for patients with metastatic biliary cancer given the identification of targetable pathways, including fibroblast growth factor receptor and isocitrate dehydrogenase 1, for which there are approved treatments. HER2 has emerged as a target in metastatic biliary cancer, with studies finding 5% to 15% of cancers positive for overexpression or gene amplification.

Investigators now report results of an industry-sponsored, phase 2 basket study (SGNTUC-019) testing the combination of tucatinib — a HER2 tyrosine kinase inhibitor — and trastuzumab in patients with HER2-positive advanced biliary cancer that progressed on first-line gemcitabine/cisplatin–based chemotherapy. Local testing for HER2 was permissible via immunohistochemistry, fluorescence in situ hybridization, or next generation sequencing of tissue or blood.

Of 30 patients, half were men, 77% were Asian, half had gallbladder primaries, and half had intrahepatic or extrahepatic cholangiocarcinomas. During a median follow-up of 10.8 months, the primary endpoint of antitumor response rate was 46.7%, and duration of response was 6 months. The median progression-free survival was 5.5 months; median overall survival was 15.5 months. Treatment-related grade 3 or 4 serious adverse events were uncommon and attributable to tucatinib in 10% of patients and to trastuzumab in 6.7%; grade 3 diarrhea occurred in 6.6%.

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