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Jan 15, 2024

A second big bang? The radical idea rewriting dark matter’s origins

Posted by in categories: cosmology, physics

The enduring mystery of dark matter has led some physicists to propose that it was forged in a distinct moment of cosmic creation, potentially transforming our view of the early universe.

By Stuart Clark

Jan 15, 2024

Gas diffusion enhanced electrode with ultrathin superhydrophobic macropore structure for acidic CO2 electroreduction

Posted by in category: sustainability

Carbon dioxide electroreduction in acidic environments has been suboptimal. Here, the authors addressed this issue by designing a gas diffusion electrode with a special metal structure, which achieves efficient electroreduction while conducting a systematic investigation of the underlying mechanism.

Jan 15, 2024

Dark Matter Could Map the Universe’s Early Magnetic Fields

Posted by in category: cosmology

So the idea is that intergalactic magnetic fields would tend to cluster electrons and ionized intergalactic hydrogen along their field lines, making those regions of the intergalactic voids just slightly denser than the rest of the void. This would cause dark matter to cluster a bit along the field lines as well. The gravitational effect would be extremely tiny, but over the entire history of the Universe, it would add up. So if primordial magnetic fields did form in the early Universe, tendrils of dark matter should be present along the same lines.

In a recent work in Physical Review Letters the authors argue that this effect would produce minihalos of dark matter. Just as galaxies are surrounded by a halo of dark matter due to gravitational clustering, faint halos of dark matter should exist around primordial magnetic field lines to do the gravitational tug of ionized matter along the field lines.

What’s interesting about this idea is that over time the charged ions and electrons would interact with the primordial magnetic fields and tend to cancel them out. The ions and electrons could even merge to create neutral hydrogen, so in the modern Universe, there would be no trace of these early magnetic fields in regular matter. But the microhalos of dark matter would still exist, and they could be seen through the gravitational lensing of distant light sources. These tendrils of dark matter could be the only evidence remaining of the earliest magnetic fields in the cosmos.

Jan 15, 2024

Black Holes and Neutron Stars are Finally Linked to Supernovae

Posted by in category: cosmology

A supernova in a nearby galaxy resulted in a compact massive object, providing a link between supernovae, black holes, and neutron stars.

Jan 15, 2024

Saturday Citations: The Dark Energy Survey; the origins of colorblindness; the evolution of heads

Posted by in categories: cosmology, quantum physics

The Dark Energy Survey took an entire decade to produce a value for the cosmological constant—and it’s smaller than you might think! There were other stories as well, including one about primeval black holes, and because I am inescapably drawn by the relentless gravity of black hole news, it’s included below, along with two other stories related in one way or another to heads.

Dogs’ primary sense is olfactory, and if their visual perception flags something interesting in the environment, the first thing they do is stick their cute little noses in it. But the opposite is true for humans; we are able to perceive millions of colors, but only a fraction of the olfactory stimuli dogs are usually way too engaged with.

If you smell in your house, you go looking for the source with your cute little retinas and their super-dense constellation of photoreceptive cells to determine that one of the gas knobs on the stove is open. Researchers at Johns Hopkins University grew retinal organoids in a lab to determine how human visual perception develops.

Jan 15, 2024

Top 10 newest and most advanced humanoid robots in the world. Humanoid robot technology | Pro Robots

Posted by in categories: Elon Musk, robotics/AI, space travel, sustainability

We are already living in the era of the fourth industrial revolution, but in the near future we will be facing another one that could really change everything. We are talking about the revolution of humanoid robots — versatile, intelligent and dexterous machines that can not only help, but also replace humans in tight places. In this video, we’ll tell you about the top 10 newest and most advanced humanoid robots in the world, and what technologies will make them truly versatile! Onward to a brighter future)

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Jan 15, 2024

A college senior used AI to try and disprove the long-held belief that all fingerprints are unique

Posted by in category: robotics/AI

A college student published a study which he says disproves the long-held belief that all fingerprints are unique, leading to pushback among experts.

Jan 15, 2024

The tale of two clocks: Advancing the precision of timekeeping

Posted by in category: particle physics

Historically, JILA (a joint institute established by the National Institute of Standards and Technology [NIST] and the University of Colorado Boulder) has been a world leader in precision timekeeping using optical atomic clocks. These clocks harness the intrinsic properties of atoms to measure time with unparalleled precision and accuracy, representing a significant leap in our quest to quantify the most elusive of dimensions: time.

Jan 15, 2024

Physicists identify overlooked uncertainty in real-world experiments

Posted by in categories: chemistry, information science, physics

The equations that describe physical systems often assume that measurable features of the system—temperature or chemical potential, for example—can be known exactly. But the real world is messier than that, and uncertainty is unavoidable. Temperatures fluctuate, instruments malfunction, the environment interferes, and systems evolve over time.

Jan 15, 2024

Cancer Vaccine Safe, Induces T-Cell Responses for KRAS-Mutated Tumors

Posted by in category: biotech/medical

FRIDAY, Jan. 12, 2024 (HealthDay News) — For patients with immunotherapy recalcitrant KRAS-mutated tumors, the cancer vaccine ELI-002 2P is safe and induces T-cell responses, according to a study published online Jan. 9 in Nature Medicine.

Noting that the cancer vaccine ELI-002 2P enhances lymph node delivery and immune response using Amphiphile (Amph)-modification of G12D and G12R mutant KRAS (mKRAS) peptides (Amph-Peptides-2P) together with CpG oligonucleotide adjuvant (Amph-CpG-7909), Shubham Pant, M.D., M.B.B.S., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues treated 25 patients (20 with pancreatic cancer; five with colorectal cancer) positive for minimal residual mKRAS disease after locoregional treatment in a phase 1 study involving fixed-dose Amph-Peptides-2P and ascending dose Amph-CpG-7909.

The researchers found no dose-limiting toxicities; the recommended phase 2 dose was 10.0 mg Amph-CpG-7909. Overall, 21, 21, and six patients (84, 84, and 24 percent) had direct ex vivo mKRAS-specific T-cell responses, tumor biomarker responses, and biomarker clearance, respectively. Median relapse-free survival was 16.33 months. There was a correlation seen for efficacy with T-cell response; the median tumor biomarker reduction was −76.0 versus −10.2 percent. Median relapse-free survival was not reached compared with 4.01 months (hazard ratio, 0.14).

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